Lead Poisoning (DBCOND0027862)

Identifiers

Synonyms

Poisoning, Lead / Lead poisoning / Toxic effects of lead and its compounds / Toxic effect of lead and its compounds, accidental (unintentional) / Lead and/or lead compound poisoning (disorder) / Saturnism / Toxic effect of unspecified lead compound / Toxic effects of other metals / Toxic effect of other metals, accidental (unintentional) / Heavy Metal Poisoning / Metal poisoning / Toxic effect of metals

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Calcium saccharate	Pharmaceutic Aid (Stabilizer)	No drug targets
Dimercaprol	A chelating agent used as an antidote to arsenic, gold, and mercury poisoning, as well as acute lead poisoning in combination with edetate calcium disodium.	Arsenictarget Cadmiumtarget Mercurytarget Amyloid-beta precursor proteintarget
Edetate calcium disodium anhydrous	A chelating agent used to treat lead poisoning.	Manganese cationtarget Irontarget Leadtarget Adenosine deaminaseenzyme Serum paraoxonase/lactonase 3enzyme Aromataseenzyme Cytochrome P450 3A4enzyme Serum paraoxonase/arylesterase 1enzyme
Edetic acid	A chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias.	Leadtarget Irontarget Manganese cationtarget Adenosine deaminaseenzyme Serum paraoxonase/lactonase 3enzyme Aromataseenzyme
Penicillamine	A chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis.	Solute carrier organic anion transporter family member 1B1transporter Coppertarget
Succimer	A mercaptodicarboxylic acid heavy metal chelator used in the treatment of heavy metal poisoning.	Leadtarget Mercurytarget Cadmiumtarget Arsenictarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00285532	Identifying Residential Hazards Using Home Test Kits	No drug interventions	Not Available	Not Available	completed
NCT00011661	Social Network Based Intervention to Reduce Lead Exposure Among Native American Children	No drug interventions	prevention	Not Available	completed
NCT02346188	Effects of Iron and/or Zinc Supplementation in Mexican School Children Exposed to Lead	No drug interventions	treatment	Not Available	completed
NCT00926406	Environmental Exposure to Lead and Its Health Effects on Patients With Maintenance Hemodialysis	No drug interventions	treatment	Not Available	unknown_status
NCT00013858	Environmental Contaminants and Infant Development	No drug interventions	Not Available	Not Available	completed
NCT00374894	The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning	Dimercaptosuccinic acid	Not Available	Not Available	completed
NCT05265572	Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump	No drug interventions	prevention	Not Available	unknown_status
NCT04498845	RECLEAN Pilot Study	No drug interventions	prevention	Not Available	terminated
NCT00931905	Homeopathic Preparation Plumbum Metallicum for Lead Poisoning	No drug interventions	treatment	4	completed
NCT03256383	Plan for Testing Fingerstick Bloods on Magellan Systems	No drug interventions	Not Available	Not Available	unknown_status
NCT00014885	Bone Lead Levels and College Achievement Scores	No drug interventions	Not Available	Not Available	completed
NCT05744752	Effects of Allium Sativum and Moringa Oleifera Extract on Dental Enamel	No drug interventions	prevention	Not Available	active_not_recruiting
NCT03408275	Dietry Pattern and Lead Levels in Pregnancy	No drug interventions	Not Available	Not Available	completed
NCT01573013	Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children	No drug interventions	health_services_research	Not Available	completed
NCT00013819	Exposure, Dose, Body Burden and Health Effects of Lead	No drug interventions	Not Available	Not Available	completed
NCT05950386	Effects of Lead Exposure on Ferroptosis Pathway	No drug interventions	Not Available	Not Available	recruiting
NCT00552630	Penicillamine Chelation for Children With Lead Poisoning	No drug interventions	treatment	2 / 3	withdrawn
NCT00011726	Lead Mobilization & Bone Turnover in Pregnancy/Lactation	No drug interventions	Not Available	Not Available	completed
NCT01739166	QI Study of a Practice Facilitator's Impact in Working With Clinics on Improving Dental, Lead & Obesity Measures for Children	No drug interventions	Not Available	Not Available	completed
NCT00011674	Early Exposure to Lead and Adolescent Development	No drug interventions	Not Available	Not Available	completed
NCT00012480	Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm	No drug interventions	Not Available	Not Available	completed
NCT00023101	Lead, Endocrine Disruption and Reproductive Outcomes	No drug interventions	Not Available	Not Available	completed
NCT00000104	Does Lead Burden Alter Neuropsychological Development?	No drug interventions	Not Available	Not Available	completed
NCT00285610	Early Exposure to Lead and Adult Antisocial Outcomes	No drug interventions	Not Available	Not Available	completed
NCT00004838	Randomized Study of Succimer (Dimercaptosuccinic Acid) on Growth of Lead-Poisoned Children	Succimer	treatment	Not Available	completed