Calcium saccharate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Calcium saccharate
DrugBank Accession Number
DB13962
Background

Pharmaceutic Aid (Stabilizer)

Type
Small Molecule
Groups
Approved, Experimental
Structure
Weight
Average: 248.2
Monoisotopic: 247.9845081
Chemical Formula
C6H8CaO8
Synonyms
  • Calcii saccharas
  • Calcium D-glucarate
  • Calcium D-saccharate
  • Calcium glucarate
  • Calcium saccharate
  • Sacarato calcico
  • Saccharate de calcium
  • Saccharated lime
External IDs
  • CCRIS 3259
  • NSC 122011

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to reverseFluoride poisoningCombination Product in combination with: Calcium gluconate (DB11126)•••••••••••••••••••••• ••••••••
Used in combination to manageHyperkalemiaCombination Product in combination with: Calcium gluconate (DB11126)•••••••••••••••••••••• ••••••••
Used in combination to manageHypermagnesemiaCombination Product in combination with: Calcium gluconate (DB11126)•••••••••••••••••••••• ••••••••
Used in combination to reversePoisoning, leadCombination Product in combination with: Calcium gluconate (DB11126)•••••••••••••••••••••• ••••••••
Used in combination to treatAcute symptomatic hypocalcemiaCombination Product in combination with: Calcium gluconate (DB11126)•••••••••••••••••• •••••••• •••• ••••••••••••••••• ••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Calcium "Fresenius" - AmpullenCalcium saccharate (0.036 g) + Calcium gluconate (0.95 g)Injection, solutionIntravenousFresenius Kabi Austria Gmb H1987-09-01Not applicableAustria flag
CALCIUM GLUCONATE INJECTION USP 10%Calcium saccharate (4.5 mg/ml) + Calcium gluconate (94 mg/ml)InjectionIntravenousFRESENIUS KABI (SINGAPORE) PTE LTD1995-11-24Not applicableSingapore flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
SST07NLK7J
CAS number
5793-88-4
InChI Key
UGZVNIRNPPEDHM-SBBOJQDXSA-L
InChI
InChI=1S/C6H10O8.Ca/c7-1(3(9)5(11)12)2(8)4(10)6(13)14;/h1-4,7-10H,(H,11,12)(H,13,14);/q;+2/p-2/t1-,2-,3-,4+;/m0./s1
IUPAC Name
calcium (2R,3S,4S,5S)-2,3,4,5-tetrahydroxyhexanedioate
SMILES
[Ca++].[H][C@](O)(C([O-])=O)[C@@]([H])(O)[C@]([H])(O)[C@]([H])(O)C([O-])=O

References

General References
Not Available
ChemSpider
136477
RxNav
1907
ChEMBL
CHEMBL2104217
Wikipedia
Saccharic_acid

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionIntravenous
InjectionIntravenous94 mg/ml
CapsuleOral
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility90.1 mg/mLALOGPS
logP-0.78ALOGPS
logP-3.1Chemaxon
logS-0.53ALOGPS
pKa (Strongest Acidic)2.83Chemaxon
pKa (Strongest Basic)-3.7Chemaxon
Physiological Charge-2Chemaxon
Hydrogen Acceptor Count8Chemaxon
Hydrogen Donor Count4Chemaxon
Polar Surface Area161.18 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity59.81 m3·mol-1Chemaxon
Polarizability16.24 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at January 17, 2018 17:25 / Updated at June 15, 2024 18:58