Smith Lemli Opitz Syndrome (DBCOND0028408)

Identifiers

Synonyms

Smith-Lemli-Opitz Syndrome / Smith-Lemli-Opitz syndrome (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT05047354	Biochemical and Phenotypical Aspects of Smith-Lemli-Opitz Syndrome and Related Disorders of Cholesterol Metabolism	No drug interventions	Not Available	Not Available	recruiting
NCT01110642	Novel Treatment for Syndromic Ichthyoses	Lovastatin	treatment	2	withdrawn
NCT01413425	A Long-Term Study of Cholesterol Supplements for Smith-Lemli-Opitz Syndrome	No drug interventions	Not Available	Not Available	withdrawn
NCT00001721	Study of Smith-Lemli-Opitz Syndrome	Cholesterol	Not Available	Not Available	completed
NCT05642221	Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls	No drug interventions	Not Available	Not Available	recruiting
NCT03720990	Smith-Lemli-Opitz Syndrome and Cholic Acid	Cholic Acid	treatment	1 / 2	completed
NCT00004347	Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz Syndrome	No drug interventions	treatment	2	unknown_status
NCT01434745	SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol Supplementation	Simvastatin	treatment	Not Available	terminated
NCT00017732	Estimation of the Carrier Frequency and Incidence of Smith-Lemli-Opitz Syndrome in African Americans	No drug interventions	Not Available	Not Available	completed
NCT01356420	Sterol and Isoprenoid Disease Research Consortium: Smith-Lemli-Opitz Syndrome	No drug interventions	treatment	Not Available	terminated
NCT00272844	Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome	Cholesterol	treatment	1 / 2	completed
NCT03655223	Early Check: Expanded Screening in Newborns	No drug interventions	Not Available	Not Available	enrolling_by_invitation
NCT01773278	Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)	Cholesterol Probucol	treatment	2	recruiting
NCT00114634	Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome	No drug interventions	treatment	2	completed
NCT05687474	Baby Detect : Genomic Newborn Screening	No drug interventions	Not Available	Not Available	recruiting
NCT00064792	Simvastatin Therapy in Smith-Lemli-Opitz Syndrome	Simvastatin	treatment	2	completed
NCT00070850	Prenatal Screening For Smith-Lemli-Opitz Syndrome	No drug interventions	Not Available	Not Available	completed