Diabetic Nephropathy (DBCOND0028920)

Identifiers

Synonyms
Diabetic Nephropatia / Diabetic Nephropathies / Diabetic nephropathy / Diabetic kidney disease / Diabetic nephropathy NOS / Disorder of kidney due to diabetes mellitus (disorder) / Diabetic renal disease / Diabetes with renal manifestations

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Benazepril
An ACE inhibitor prodrug used to treat hypertension.
Canagliflozin
A sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM.
Candesartan cilexetil
An angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy.
Captopril
An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
Enalapril
A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure.
Enalaprilat
An antihypertensive agent used for the management of hypertension when oral therapy is not practical.
Eprosartan
An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
Irbesartan
An angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure.
Lisinopril
An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction.
Losartan
An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
Olmesartan
An angiotensin receptor blocker (ARB) used in the treatment of hypertension.
Perindopril
An ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction.
Quinapril
An ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease.
Ramipril
An ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure.
Telmisartan
An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
Valsartan
An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00363987
Controlled Study to Evaluate Efficacy and Safety of α-KA Tab With Low Protein Diet (LPD) in Delaying the Progress of Type 2 Diabetic Nephropathy (DN)treatment4completed
NCT00317954
Spironolactone in Diabetic Nephropathytreatment4completed
NCT00734253
Safety and Efficacy Study of Pyridorin in Patients With Nephropathy Due to Type 2 DiabetesNo drug interventionsprevention2completed
NCT02829177
Microalbuminuria and Allopurinol in Type 1 Diabetesprevention4completed
NCT01889277
Safety, Tolerability and Pharmacokinetic Study of MT-3995 in Subjects With Diabetic Nephropathytreatment1 / 2completed
NCT00782847
Evaluation Study for the Programme DiaNe for People With Diabetic NephropathyNo drug interventionssupportive_care3completed
NCT00498147
Determining Rates of Cardiovascular Complications Among Patients of a Managed Diabetes Care ProgramNo drug interventionsNot AvailableNot Availableunknown_status
NCT00287183
6-Month Safety And Efficacy Study Of TTP488 In Patients With Type 2 Diabetes And Persistent AlbuminuriaNo drug interventionstreatment2completed
NCT00106561
Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidneyprevention2 / 3completed
NCT01768611
SLC2A1 Variants and Diabetic NephropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT02409511
Microalbuminuria as a Cardiovascular Risk Factor (PRECISED Substudy)No drug interventionsNot AvailableNot Availableunknown_status
NCT03436693
Efficacy and Safety of Canagliflozin (TA-7284) in Patients With Diabetic Nephropathytreatment3completed
NCT06123871
Expression Analysis of Urinary Exosome in Type 2 Diabetic Kidney Disease and Evaluation of Its Clinical Diagnostic ValueNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02502071
Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 Diabetestreatment4completed
NCT00340678
Renoprotection in Early Diabetic Nephropathy in Pima Indianstreatment3completed
NCT00364988
Pioglitazone and Losartan Provides Additional RenoprotectiontreatmentNot Availablecompleted
NCT02150707
The Differential Effects of Diabetes Therapy on InflammationNot AvailableNot Availablecompleted
NCT01252056
A Clinical Study to Evaluate the Efficacy and Safety of Cilostazol and Probucol in Combination on Patients With Diabetic Nephropathytreatment4completed
NCT01858532
Study Of Diabetic Nephropathy With Atrasentantreatment3terminated
NCT05061459
The Expression of circANKRD36 as a New Biomarker of Diabetic NephropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01273675
An Investigation on the Effect of Candesartan on Early Diabetic NephropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02410499
Efficacy and Safety of Weekly Subcutaneous MLN1202 in Improving Diabetic Nephropathy in Participants With Macroalbuminuriatreatment2withdrawn
NCT00301249
The Family Investigation of Nephropathy and Diabetes StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02625649
Effect of Gastric Bypass Surgery on Diabetes Status and Microvascular Complications in Obese Type 2 Diabetic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01003236
Evaluating the Renoprotective Effect of Milk Thistle Extract on Patients With Type II Diabetic Nephropathytreatment2completed
NCT04981613
Study on the Efficacy and Safety of a Novel Tripterygium Wilfordii Preparation in Reducing Proteinuria in Patients With Diabetic NephropathyNo drug interventionstreatmentNot Availablerecruiting
NCT00565318
Benfotiamine in Diabetic Nephropathytreatment4completed
NCT01424319
Reducing Residual Albuminuria in Subjects With Diabetes and Nephropathy With Atrasentantreatment2completed
NCT00171119
A Study in Patients With Diabetes Mellitus Type II of the Effect on Albuminuria of 24 Week Treatment With Valsartan, Benazepril, and Valsartan+Benazepriltreatment4terminated
NCT01331317
Effect of a Vitamin D Analogue vs Placebo on p-NT-proBNP in Patients With Type 1 DM and Diabetic Nephropathytreatment4completed
NCT03658317
Renal Resisitive Index as an Indicator of the Progression of Diabetic NephropathyNo drug interventionsdiagnosticNot Availableunknown_status
NCT01726816
Efficacy and Safety Study of Probucol in Patients With Diabetic Nephropathytreatment2completed
NCT02276196
Effect of LIXIsenatide on the Renal Systemtreatment4completed
NCT01458158
Matrix Metalloproteinases in Atherosclerosis of Chronic Kidney DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01105858
Molecular and Clinical Profile of Diabetes Mellitus and Its ComplicationsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02477163
Ayurvedic Management of Chronic Kidney DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT01265563
N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathytreatment2completed
NCT00067886
Matrix Metalloproteinases and Diabetic NephropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT00253786
Study for the Effectiveness of Intensive Therapy Aiming at a Remission of Diabetic NephropathyNo drug interventionstreatmentNot Availablecompleted
NCT04534439
Safety, Tolerability and Renal Effects of APX-115 in Subjects With Type 2 Diabetes and Nephropathytreatment2completed
NCT00535925
Nephropathy In Type 2 Diabetes and Cardio-renal Eventsprevention4completed
NCT05492630
Single and Multiple Dose Safety, Tolerability, PK and Food Effect Study of HEC73077 in Healthy SubjectsNo drug interventionstreatment1completed
NCT02768948
Telmisartan Promotes the Differentiation of Monocytes Into Macrophages M2 in Diabetic Nephropathy?basic_scienceNot Availablecompleted
NCT00044148
The Effect of LY333531 on Protein in the Urine in Patients With Type 2 Diabetestreatment2completed
NCT02345057
A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Type 2 Diabetic Subjects With Microalbuminuriatreatment2completed
NCT01440257
A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuriatreatment2completed
NCT00171574
Antiproteinuric Effect of Valsartan and Lisinopriltreatment4completed
NCT05695573
Assessment of Urinary Uromodulin and the Corresponding Gene Expression as a Biomarker of Diabetic NephropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT00664027
Phase IIa Trial to Determine the Effects of Bardoxolone Methyl on Renal Function in Patients With Diabetic Nephropathytreatment2completed
NCT00309127
Effects of Disease Management on Development of End Stage Renal Disease in Type 2 Diabetic Patients With NephropathyNo drug interventionstreatmentNot Availablecompleted
NCT00342927
Family Investigation of Nephropathy and Diabetes (F.I.N.D.)No drug interventionsNot AvailableNot Availablerecruiting
NCT00738660
Efficacy of Telmisartan and the Combination of Telmisartan and Ramipril in type1 Diabetes Patients With Nephropathytreatment3completed
NCT00320060
Effect of Pyridorin in Patients With Diabetic NephropathyNo drug interventionstreatment2completed
NCT01215994
Estimation of Glomerular Filtration Rate (GFR) in Patients With Type 2 Diabetes Mellitus.No drug interventionsNot AvailableNot Availableunknown_status
NCT04881994
A Study to Learn How Finerenone (BAY94-8862) Moves Into, Through and Out of the Body, How it Affects the Body, and How Safe it is in Adult Participants With Different Degrees of Reduced Liver Function and in Healthy Participants With Similar Age, Weight and Gender Distributionbasic_science1completed
NCT02035891
Low-dose Colchicine in Patients With Type 2 Diabetes Mellitus and MicroalbuminuriatreatmentNot Availableunknown_status
NCT01163591
To Assess the Accuracy of the eZscan Study in the Screening for Diabetic NephropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT02065791
Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathytreatment3completed
NCT02816762
CPAP Effect on Albuminuria in Patients With Diabetic Nephropathy and Obstructive Sleep ApneaNo drug interventionstreatment4completed
NCT01399580
A Prospective, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate Efficacy and Safety of Atrasentan, Including Thoracic Bioimpedance, in Type 2 Diabetic Subjects With Nephropathytreatment2completed
NCT02204280
The Significance of Urine UbA52 In the Diagnosis of Diabetic NephropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT04125329
Umbilical Cord Mesenchymal Stem Cells Therapy for Diabetic Nephropathytreatment0unknown_status
NCT00811889
Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Diseasetreatment2completed
NCT03407989
SWIDINEP a Swiss Diabetic Nephropathy CohortNo drug interventionsNot AvailableNot Availableunknown_status
NCT06376240
The Effect of Pyridoxamine Supplementation on Microvascular Function in Type 2 DiabetesNo drug interventionstreatmentNot Availablerecruiting
NCT01673204
Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathyscreening4unknown_status
NCT00561704
Adiponectin in Obese Women With T2DN and Effects by RAS BlockertreatmentNot Availablecompleted
NCT00774904
Adiponectin and Insulin Resistance in Diabetic NephropathytreatmentNot Availablecompleted
NCT02501772
The Evaluation of Effect of Sanyinjiao (SP6) Acupressure on Early Diabetic NephropathyNo drug interventionstreatmentNot Availableunknown_status
NCT00484068
Chicken-Diet vs. Enalapril to Reduce AlbuminuriatreatmentNot Availablecompleted
NCT01316068
Effect of Sulodexide on Albuminuria in Chinese Type 2 Diabetic Patientstreatment4unknown_status
NCT00708981
Combined Diabetes-Renal Multifactorial Intervention In Patients With Advanced Diabetic Nephropathy (ADN)No drug interventionstreatmentNot Availablecompleted
NCT01588795
Renal Denervation in Diabetic Nephropathytreatment4completed
NCT02928250
Role of Carnosine as an Adjuvant Therapy for Diabetic Nephropathy in Pediatrics With Type 1 DiabetesNo drug interventionstreatmentNot Availablecompleted
NCT00361023
Effects of Losartan on Insulin Sensitivity and Secretion in Type 2 Diabetes and NephropathytreatmentNot Availablecompleted
NCT00140543
European Trial of Immunosuppression in SPK Txtreatment3completed
NCT02156843
Pyridorin in Diabetic NephropathyNo drug interventionstreatment3terminated
NCT02194790
Effect of Integrated CKD Care Program in Early Diabetic Nephropathy in Primary Health Care Setting.No drug interventionspreventionNot Availablecompleted
NCT00920764
A Study of Atrasentan on Reducing Albuminuria in Type 2 Diabetic Nephropathy Treated With Renin-Angiotensin System Inhibitorstreatment2completed
NCT01005121
Colchicine for Diabetic Nephropathytreatment2unknown_status
NCT00024921
The Genetics of Kidneys in Diabetes (GoKinD) StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06482021
Comparative Effectiveness Of Low Extra-Corporeal Shock Wave Versus Acetylcholine Iontophoresis On Type2 Diabetic NeuropathyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00320021
Effect of Pyridorin in Patients With Diabetic NephropathyNo drug interventionstreatment2completed
NCT02384902
Effect of Low GI/ Glycemic Load (GL) Diet in Diabetic Nephropathy PatientsNo drug interventionstreatmentNot Availablecompleted
NCT04127084
Effects of SGLT2 Inhibition Treatment on Different Levels of Albuminuria in Patients With Type 2 Diabetestreatment4unknown_status
NCT00419484
Effect of Pioglitazone on Cardiovascular Outcome on Higashi-Saitama Trial in Patients With Type 2 DiabetesNot AvailableNot Availablecompleted
NCT03804879
Safety, Tolerability and Efficacy of Nidufexor in Patients With Diabetic Nephropathytreatment2completed
NCT01028287
Adrenocorticotropic Hormone (ACTH) Treatment of Nephrotic Range Proteinuria in Diabetic Nephropathy (NRDN)treatment4completed
NCT01843387
Safety and Efficacy of Mesenchymal Precursor Cells in Diabetic NephropathyNo drug interventionstreatment1 / 2completed
NCT00421733
The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitorstreatment2completed
NCT02327754
Effect of Topiroxostat on Urinary Albumin Excretion Early Stage Diabetic Nephropathy and Hyperuricemia With or Without Gouttreatment2completed
NCT06097351
Expression Analysis of Urinary Exosome in Type 2 Diabetic Nephropathy and Evaluation of Its Clinical Diagnostic ValueNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00141453
ORIENT: Olmesartan Reducing Incidence of End Stage Renal Disease in Diabetic Nephropathy Trialtreatment3completed
NCT04721847
Pain Neuroscience Education in Diabetic NeuropathyNo drug interventionstreatmentNot Availablecompleted
NCT01447147
A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Diabetic Nephropathytreatment2completed
NCT01923597
Effect of Green Tea (Epigallocatechin Gallate) on Albuminuria in Patients With Diabetic Nephropathy.treatment2completed
NCT00063583
Pirfenidone: A New Drug to Treat Kidney Disease in Patients With Diabetestreatment1 / 2completed
NCT01712061
A Phase 2 Multi-Center Study To Evaluate The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist In Adults With Type 2 Diabetes And Overt Nephropathytreatment2completed
NCT00120328
To Determine the Effects of Avosentan on Doubling of Serum Creatinine, End Stage Renal Disease and Death in Diabetic NephropathyNo drug interventionsprevention3terminated
NCT00913393
Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB Therapytreatment2terminated
NCT00067678
Soy Protein in Early Diabetic NephropathyNo drug interventionstreatment1 / 2completed
NCT02689778
Effect of Pirfenidone on Glomerular Filtration Rate and Albuminuria in Patients With Diabetic Nephropathytreatment3completed
NCT03413215
Effects of Multidisciplinary Intensive Targeted Care in Improving Diabetes Outcomes: a Pilot Study in SingaporeNo drug interventionspreventionNot Availableunknown_status
NCT00498537
Spironolactone for Reducing Proteinuria in Diabetic NephropathytreatmentNot Availablecompleted
NCT01015937
Effect of Turmeric on Diabetic NephropathytreatmentNot Availablecompleted
NCT00594152
Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT)No drug interventionstreatment3completed
NCT02237352
Mechanisms of Diabetic Nephropathy in EcuadorNo drug interventionsNot AvailableNot Availableunknown_status
NCT00353600
Delaying the Progression of Diabetic Nephropathy in Pima IndiansNo drug interventionsNot AvailableNot Availablecompleted
NCT00065559
Treatment of Diabetic NephropathytreatmentNot Availableterminated
NCT00320970
Angiotensin II Antagonism of TGF-Beta 1treatmentNot Availablecompleted
NCT00311870
Renoprotective Effect of Nisoldipine and Lisinopril in Type 1 Diabetic Nephropathytreatment4completed
NCT01566006
Mycophenolate Mofetil, Carnitine and PDE5 Inhibitor, Three Potential Treatments for Resistant Proteinuria Slowing Diabetic Nephropathy DeteriorationtreatmentNot Availableunknown_status
NCT02628106
Lipo-prostaglandin E1 Improves Renal Hypoxia Evaluated by BOLD-MRI in Patients With Diabetic Nephropathytreatment4completed
NCT01356849
Evaluate the Efficacy and Safety of Once Daily Administration of Atrasentan Tablets (Low and High) Compared to Placebo in Reducing Residual Albuminuria in Type 2 Diabetic Patients With Nephropathy Who Are Treated With the Maximum Tolerated Labeled Dose of a Renin Angiotensin System (RAS) Inhibitortreatment2completed
NCT00663949
Assessment of the Effect of Captopril Versus Combination of Captopril and Pentoxifylline on Reducing Proteinuria in Type 2 Diabetic Nephropathytreatment2 / 3completed
NCT01601236
Acthar for Treatment of Proteinuria in Diabetic Nephropathy Patientstreatment2completed
NCT00557518
Study of Alagebrium in Patients With Insulin-Dependent Type 1 Diabetes and Microalbuminuriatreatment2terminated
NCT01796418
Beraprost Sodium and Arterial Stiffness in Patients With Type 2 Diabetic NephropathytreatmentNot Availableunknown_status
NCT00240019
Maximizing the Benefit of Renin-Angiotensin Blocking Drugs in Diabetic Renal Disease.treatmentNot Availablecompleted
NCT01875341
Role of Sleep Apnea and Sympathetic Activity in Resistant Hypertensive Patients.No drug interventionstreatment3completed
NCT02040441
Proteomic Prediction and Renin Angiotensin Aldosterone System Inhibition Prevention Of Early Diabetic nephRopathy In TYpe 2 Diabetic Patients With Normoalbuminuriadiagnostic2 / 3completed
NCT01068041
Effects of PH3 in Diabetic NephropathyNo drug interventionsprevention2completed
NCT01307917
Flavonoids in the Treatment of Endothelial Dysfunction in Children With DiabetesNo drug interventionspreventionNot Availablewithdrawn
NCT01802034
Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)No drug interventionsNot AvailableNot Availablerecruiting
NCT00544934
Multiple Dose Trial of Anti-glycation Agent GLY-230 in Healthy and Diabetic SubjectsNo drug interventionstreatment1 / 2completed
NCT01703234
FGF-23 and Endothelial Dysfunction in Diabetic Proteinuric Patientstreatment4completed
NCT00914524
Study of Olmesartan Medoxomil (CS-866) in Patients With Chronic Glomerulonephritis or Diabetic Nephropathytreatment2completed
NCT01756716
A Study to Evaluate Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of MT-3995 in Type II Diabetic Nephropathy Subjects With Albuminuria and Moderately Decreased GFRtreatment2completed
NCT00315016
Eplerenone, ACE Inhibition and Albuminuriatreatment2completed
NCT00296296
Immunosuppression Impact on the Metabolic Control of Kidney Transplant With Pre-Existing Type 2 Diabetes (DM)treatment4completed
NCT01810822
Sex-specific Association With Kidney DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04562025
Clinical Research of UC-MSCs in the Treatment of Diabetic NephropathytreatmentNot Availableunknown_status
NCT00893425
Effect of Renin Angiotensin System Blockade on the Fas Antigen (CD95) and Asymmetric Dimethylarginine (ADMA) Levels in Type-2 Diabetic Patients With Proteinuriatreatment4completed
NCT04027530
Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study.prevention4completed
NCT01129557
Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney Diseasetreatment4terminated
NCT00497666
Association Between Rosiglitazone Use and Clinical Course of Diabetic Nephropathy: Population-Based StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00004266
Drugs for High Blood Pressure and High Cholesterol in American Indians With Type 2 Diabetesprevention3completed
NCT00556465
Efficacy of N-Acetylcysteine in Treatment of Overt Diabetic Nephropathytreatment2 / 3completed
NCT02517320
Efficacy and Safety of MT-3995 in Patients With Diabetic Nephropathytreatment2completed
NCT01130727
The Effect of Green Tea or Cocoa Extracts in Endothelial Dysfunction in Patients With Diabetes MellitusNo drug interventionstreatmentNot Availablecompleted
NCT00118976
Maximal Dose of Angiotensin Converting Enzyme (ACE) Inhibitor for Treatment of Diabetic Kidney DiseasepreventionNot Availablecompleted
NCT00362960
Olmesartan Medoxomil and Diabetic Nephropathytreatment3completed
NCT02704494
Resveratrol's Effects in Diabetic Nephropathytreatment0completed
NCT02914691
Effects of Dapagliflozin Treatment on Urinary Proteomic Patterns in Patients With Type 2 DiabetesNo drug interventionsprevention4completed
NCT00518362
To Compare the Efficacy and Safety of Tripterygium (TW) Versus Valsartan in the Diabetic Nephropathy (DN)No drug interventionstreatmentNot Availablecompleted
NCT00312780
Study of XL784 in Patients With Albuminuria Due to Diabetic Nephropathytreatment2completed
NCT00967629
Effect of Sevelamer Carbonate on Oxidative Stress in Patients With Diabetic Nephropathytreatment1completed
NCT01779089
Minocycline and Proteinuria in Diabetic NephropathytreatmentNot Availableunknown_status
NCT06095544
Enhanced Recovery After Surgery for SPK Transplantation RecipientsNo drug interventionshealth_services_researchNot Availablecompleted
NCT02251067
Phase 2 Study to Evaluate Safety & Efficacy of VPI-2690B in Diabetic Nephropathy PatientsNo drug interventionstreatment2completed
NCT01935167
To Determine the Efficacy and Safety of DW1029M on Microalbuminuria in Patients With Diabetic NephropathyNo drug interventionstreatment2completed
NCT01113801
A Study in Participants With Diabetic Kidney DiseaseNo drug interventionstreatment2terminated
NCT02676401
An Extended Treatment Study of MT-3995 in Patients With Diabetic Nephropathytreatment2completed
NCT01476501
Vitamin D Supplementation in Diabetic Nephropathytreatment2completed
NCT02205372
Safety, Tolerability and Pharmacokinetic Study of MT-3995 at a Low Dose in Subjects With Diabetic Nephropathytreatment1 / 2completed
NCT00222846
Enhancing Adherence in Type 2 Diabetes: The ENHANCE StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01109212
The Effects of Bindarit in Diabetic Nephropathytreatment2completed
NCT00130312
Effect of Sulodexide in Overt Diabetic Nephropathytreatment4terminated
NCT01725412
Prevention of Renal Complications of Diabetes With ThiamineNo drug interventionstreatment4unknown_status
NCT01869881
Effect of Sarpogrelate On the Nephropathy in Type 2 Diabetes (SONATA Study)treatment4completed
NCT01774981
Study of LY3016859 in Participants With Diabetic Nephropathytreatment1 / 2completed
NCT01667614
Effects of Spironolactone Combination Therapy on Proteinuria, Kidney Function, and Blood Pressuretreatment2completed
NCT01743014
Ramipril and Clopidogrel in Oxidative Stress, Vascular Inflammation and Endothelial Dysfunction in Type 2 Diabetes and Diabetic Nephropathytreatment4unknown_status
NCT01371955
Impact of c242T Polymorphism of p22phox in Diabetic type1 NephropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT00097955
Safety and Efficacy of Aliskiren When Added to Standardized Losartan and Optimal Antihypertensive Therapy in Patients With Hypertension, Type 2 Diabetes and Proteinuriaother2completed
NCT01493050
The Effects of Sevelamer Carbonate on Diabetic Nephropathytreatment2completed
NCT00130208
Effect of Sulodexide in Early Diabetic Nephropathytreatment3completed
NCT00754143
Phase 1 Study of FG-3019 in Subjects With Type 1 or Type 2 Diabetes Mellitus and Diabetic Nephropathytreatment1completed
NCT01756703
A Study to Evaluate Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of MT-3995 in Type II Diabetic Nephropathy Subjects With Albuminuriatreatment2completed
NCT05330390
Study on the Population Pharmacokinetics of Levetiracetam in Epileptic Patients With Diabetic Kidney DiseaseNot AvailableNot Availableunknown_status
NCT01328821
Safety, Tolerability, and Pharmacokinetics (PK) of CTP-499treatment1completed
NCT00870402
Aldosterone in Diabetic Nephropathytreatment4unknown_status
NCT00462202
Open Label Tolerability and Safety Study of KRX-101 in Australia, New Zealand, and Hong Kongtreatment3terminated
NCT05797051
Application of Hyperspectral Imaging in the Diagnosis of Glomerular DiseasesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04750577
A Study to Test the Effect of Different Doses of BI 685509 on Kidney Function in People With Diabetic Kidney Diseasetreatment2completed
NCT06431477
Efficacy and Safety of Telmisartan Compared With Losartantreatment4recruiting
NCT01320345
The Fenofibrate And Microvascular Events in Type 1 Diabetes Eye.treatment3recruiting
NCT02690883
Effect of Exenatide on 24h-UAER in Patients With Diabetic Nephropathyprevention4completed
NCT03899883
Uric Acid Lowering Trial in Youth Onset T2Dtreatment2recruiting
NCT04869761
Stem Cell Therapy for Chronic Kidney DiseaseNo drug interventionsother1active_not_recruiting
NCT02515461
Low Energy Shockwave Therapy (LE-SWT): A Novel Treatment for Chronic Kidney DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT02017171
A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetesprevention3completed
NCT00136188
Nitric Oxide (NO) Activity and Diabetic Nephropathytreatment2 / 3completed
NCT00153088
INNOVATION Study - Telmisartan (Micardis) in Incipient Diabetic Nephropathytreatment4completed
NCT03933956
Metabolic Effects of the SGLT-2 Inhibitor Empagliflozin in Patients With Diabetic Nephropathy (MEDiaN)basic_science3terminated
NCT06147232
Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose-coTransporter Inhibitors Avoiding Kidney hypOxiatreatment4not_yet_recruiting
NCT04916132
Diabetic Nephropathy in People With Diabetes. Prevalence and Predictive FactorsNo drug interventionsNot AvailableNot Availablerecruiting
NCT03006952
Add-on Pentoxifylline to Losartan Versus Increasing Dose of Losartan on NT-PRO BNP in Type 2 Diabetics With Nephropathyprevention4completed
NCT00915200
N-Acetylcysteine and Milk Thistle for Treatment of Diabetic NephropathyNo drug interventionstreatment2completed
NCT00446459
Effects of Mycophenolate Mofetil (MMF) On Anti-HLA (Human Leukocyte Antigen)Antibody Levels In Patients Awaiting Cadaveric Renal Transplant.treatment2completed
NCT00306436
Comprehensive Management of Diabetic Patients With Renal Impairment : Impact on Blood Pressure and Glycemic ControlNo drug interventionsNot AvailableNot Availableunknown_status
NCT03889236
Dietary Interventions on Glycocalyx Dimensions in South Asian Patients With Diabetic Nephropathy.No drug interventionstreatmentNot Availablecompleted
NCT03334318
PERL Continuous Glucose Monitoring (CGM) StudyNot AvailableNot Availablecompleted
NCT05840796
To Explore the Anti-oxidative Effects and Inflammation Effects of Soy Protein to Renal Function of End Stage Diabetes Nephropathy PatientsNo drug interventionstreatmentNot Availablecompleted
NCT03284996
Doppler Ultrasound in Early Detection of Diabetic Nephropathy Type 2 Diabetes Mellitus.No drug interventionsNot AvailableNot Availableunknown_status
NCT03535935
Efficacy, Safety and Response Predictors of Adjuvant Astragalus Therapy for Diabetic Kidney DiseaseNo drug interventionstreatment2 / 3unknown_status
NCT06466135
Study of WAL0921 in Patients With Glomerular Kidney DiseasesNo drug interventionstreatment2recruiting
NCT05656963
The Influencing Factors and Mechanism of High Incidence of Thrombotic Events in Patients With MN and DKDNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04084886
TCF7L2 Gene Polymorphism and AGEs in Diabetic NephropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03325322
Inflammation and Stem Cells in Diabetic and Chronic Kidney DiseaseNo drug interventionstreatment2suspended
NCT00737126
The Effect of Folic Acid Administration in the Progression of MicroalbuminuriatreatmentNot Availablecompleted
NCT00448526
Effect of Low Protein Diet in Preventing the Progression of Diabetic NephropathyNo drug interventionspreventionNot Availableterminated
NCT05974566
Efficacy and Safety of Finerenone in Heart Failure With Reduced Ejection FractionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03618420
Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Functiondiagnostic1 / 2completed
NCT03620773
Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetesdiagnostic1 / 2active_not_recruiting
NCT03165227
This Study Tests a New Medicine Called BI 685509 in Patients That Have Kidney Problems Because of Diabetes. The Study Tests How BI 685509 is Taken up in the Body and How Well it is Tolerated (Multiple Rising Doses)No drug interventionstreatment1completed
NCT05147194
The Effects of TMZ on Diabetic Nephropathytreatment2unknown_status
NCT01200394
A Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 Diabetes And Overt Nephropathytreatment2completed
NCT03690180
Hypomagnesemia and Diabetic NephropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT05282680
The Hong Kong Diabetes BiobankNo drug interventionsNot AvailableNot Availablerecruiting
NCT06031389
Henagliflozin Delays the Progress of Diabetic Nephropathy Via Regulates Gut-Renal Axisbasic_scienceNot Availablenot_yet_recruiting
NCT03165240
This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Toleratedtreatment1completed
NCT02145572
Metabolomic Profiling in Adolescents With Obesity and DiabetesNo drug interventionsNot AvailableNot Availablecompleted
NCT01968668
Safety and Efficacy of Different Oral Doses of BAY94-8862 in Japanese Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Nephropathy (ARTS-DN Japan)treatment2completed
NCT04074668
Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin ResistanceNot AvailableNot Availablecompleted
NCT03840343
Patient-Derived Stem Cell Therapy for Diabetic Kidney DiseaseNo drug interventionstreatment1terminated
NCT05319990
Pathogenesis of Kidney Disease in Type 1 Diabetes: a Modern Kidney Biopsy Cohort (The PANDA Study)Not AvailableNot Availablerecruiting
NCT03216564
An Intervention to Examine the Effect of Vitamin D on Urine Protein Levels in Type 2 Diabetestreatment3unknown_status
NCT04235621
A Study to Understand the Genetics and Clinical Course of Focal Segmental Glomerulosclerosis (FSGS), Treatment-Resistant Minimal Change Disease (TR-MCD), and Diabetic Nephropathy (DN)No drug interventionsNot AvailableNot Availableterminated
NCT02442921
Colchicine for Diabetic Nephropathy Trialtreatment1 / 2unknown_status
NCT03573102
Effect of Sodium Glucose co Transporter 2 Inhibitor ( SGLT2) on Proteinuria in Diabetic Patientstreatment4unknown_status
NCT04029402
Molecular Analysis of Diabetic Kidney Disease BiopsiesNo drug interventionsNot AvailableNot Availablerecruiting
NCT02986984
Transformative Research in Diabetic NephropathyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04929379
A Pilot Study of Fenofibrate to Prevent Kidney Function Loss in Type 1 Diabetestreatment2recruiting
NCT03509454
PeRsOnalising Treatment Of Diabetic Nephropathy:No drug interventionsNot AvailableNot Availablecompleted
NCT00446251
Effects of Rituximab and Mycophenolate Mofetil (MMF) on Highly Sensitized Patients Awaiting Renal Transplanttreatment2completed
NCT03878277
Evaluation of Coffee Therapy for Improvement of Renal OxygenationNo drug interventionstreatment2completed
NCT02552277
A Efficacy and Safety Study of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects With Diabetic Peripheral NeuropathyNo drug interventionstreatment2completed
NCT03945747
MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes MellitusNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02410005
Intervention Using Vitamin D for Elevated Urinary Albumin Treated With Losartan in Diabetes (IDEAL)treatment2 / 3terminated
NCT00713011
Adalat XL vs Diltiazem on Proteinuria and Blood Pressure in Hypertensive Diabetic Patientstreatment3withdrawn
NCT03288571
Use of Wharton Jelly in Diabetic NephropathyNo drug interventionstreatment1 / 2unknown_status
NCT01918488
Increased Activity of a Renal Salt Transporter (ENaC) in Diabetic Kidney Diseasebasic_scienceNot Availableunknown_status
NCT05530356
Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up StudyNot AvailableNot Availableenrolling_by_invitation
NCT02001532
Arterial Stiffness and Complication Risk in Type 2 DiabetesNo drug interventionsNot AvailableNot Availablecompleted
NCT02488252
Semi-individualised Chinese Medicine Treatment as an Adjuvant Management for Diabetic NephropathyNo drug interventionstreatment2 / 3unknown_status
NCT00237952
Environmental Exposure to Lead and Progressive Renal Insufficiency in Type II Diabetic NephropathyNo drug interventionstreatmentNot Availablecompleted
NCT05718375
Phase IIb Clinical Trial for the Efficacy and Safety by CU01-1001 for 24 Weeks in Type 2 DM Patients With AlbuminuriaNo drug interventionstreatment2recruiting
NCT05357742
Basic Needs Navigation Intervention to Address Multidimensional Adversity in African Americans With Diabetic Kidney DiseaseNo drug interventionshealth_services_researchNot Availablerecruiting
NCT04705506
Gemigliptin and Biomarkers of Kidney Injury and Vascular CalcificationtreatmentNot Availablecompleted
NCT03201406
Retrospective Analysis of Renal Prognosis in Patients With Chronic Kidney DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT03137316
Prevalence of Secondary Hyperparathyroidism Among Patients With Diabetic NephropathyNo drug interventionsNot AvailableNot Availablecompleted
NCT03921216
Cholesterol Metabolism in Plasma and Interstitial Fluid Among Subjects Undergoing Hemodialysis.No drug interventionsNot AvailableNot Availablesuspended
NCT03820635
Markers of Vascular Calcification in Diabetic Nephropathy in Patients With Diabetic NephropathyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04570735
MRI Biomarkers in Diabetic Kidney DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT02682563
Renoprotective Effects of Dapagliflozin in Type 2 Diabetesprevention4completed
NCT04531163
Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathytreatment2 / 3unknown_status
NCT04799925
Hyperuricemia and Diabetic NephropathyNot AvailableNot Availableunknown_status
NCT04317430
Niclosamide Role in Diabetic Nephropathytreatment3completed
NCT04387448
A Study of TRPC5 Channel Inhibitor in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change DiseaseNo drug interventionstreatment2terminated
NCT00168857
A Prospective, Randomised, Double-blind, Double-dummy, Forced-titration, Multicentre, Parallel Group, One Year Treatment Trial to Compare Telmisartan (MICARDIS) 80 mg Versus Losartan (COZAAR) 100 mg, in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy (AMADEO Study)treatment4completed
NCT05418465
Huangqi Guizhi Wuwu Decoction in CKD Stage 2-4 Diabetic NephropathytreatmentNot Availableunknown_status
NCT03869931
Effects of Fenofibrate Therapy in Diabetic Nephropathytreatment3unknown_status
NCT01874431
Safety and Efficacy of Different Oral Doses of BAY94-8862 in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Nephropathytreatment2completed
NCT02299960
Measurement of Endothelial Function and Cardiac Output: New MethodsNo drug interventionsNot AvailableNot Availablecompleted
NCT06563791
Assessment of the Association Between Visceral Obesity and the Progression of Diabetic NephropathyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04880291
First-In-Human Study of GFB-024 in Healthy Overweight and Obese Participants, and Participants With Type 2 DiabetesNo drug interventionstreatment1completed
NCT06441591
Clinical Outcome of Vinpocetine in Diabetic Nephropathytreatment2 / 3recruiting
NCT03885362
Assessment of the Accuracy of Continuous Glucose Sensors in People With Diabetes Undergoing HaemodialysisNo drug interventionspreventionNot Availablecompleted
NCT05638880
Clinical Study to Evaluate the Possible Efficacy and Safety of Levocetirizine in Patients With Diabetic Kidney Diseasetreatment2recruiting
NCT04119167
Use of GDF15 as a Biomarker for Early Diagnosis of DM and Monitoring of Progress of Complications in AsiansNo drug interventionsNot AvailableNot Availableunknown_status
NCT01094769
Sympathetic Nervous System Inhibition for the Treatment of Diabetic Kidney Diseasetreatment4completed
NCT04755946
Possible Role of Roflumilast in Diabetic Nephropathytreatment3unknown_status
NCT04988581
Prevention In Community Clinics From Diabetic Kidney DiseaseNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT03212755
Serum Immunoglobulin (G) as a Marker of Diabetic NephropathyNo drug interventionsscreeningNot Availableunknown_status
NCT00153023
1 Year Trial Telmisartan 80 mg Versus Valsartan 160 mg in Hypertensive Type 2 Diabetic Patients With Overt Nephropathytreatment4completed
NCT00438503
Glucose in Dialysis Water in Diabetics With Chronic Renal FailureNo drug interventionstreatment4completed
NCT06224790
Perfenidone in Type 2 Diabetic Patients With Diabetic Neuropathytreatment4recruiting
NCT06217302
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Diseaseprevention3not_yet_recruiting
NCT04380584
Relation Between Plasma Apelin Level and Diabetic Nephropathy in Type 2 Diabetes Patients.No drug interventionsNot AvailableNot Availablecompleted
NCT03824379
Magnesium Supplementation in Diabetic NephropathyNo drug interventionstreatment2completed
NCT01575379
A Pilot Study of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetesprevention4terminated