Venous Insufficiency (DBCOND0029376)

Identifiers

Synonyms
Venous insufficiency / Venous (peripheral) insufficiency, unspecified / Venous peripheral insufficiency / Peripheral venous insufficiency (disorder) / Venous reflux disorder / Peripheral venous disease

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Bilberry
Not Annotated
No drug targets
Carbazochrome
Indicated for capillary and parenchymal hemorrhage (trauma, tonsillectomy, during surgery), intestinal bleeding, and thrombocytopenic purpura.
No drug targets
Centella asiatica
Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
No drug targets
Diosmin
A citrus flavonoid medication used to support vascular health.
Dobesilic acid
A medication indicated in the treatment of hemorrhoids, venous insufficiency, and other microangiopathies.
No drug targets
Hesperidin
A bioflavonoid found in a variety of nutritional supplements that is touted to have various beneficial effects on blood vessel disorders and various other conditions.
Oxerutins
A flavonoid antioxidant indicated in the treatment of venous insufficiency and capillary fragility.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06510777
PICO Venous Leg Ulcers (VLU) Reimbursement StudyNo drug interventionstreatmentNot Availablerecruiting
NCT06350695
The ROle of Compression StocKings in Heart Failure PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT06438133
Digital Supported Compression Bandaging in Patients With Chronic Edema in the Lower LimbsNo drug interventionsNot AvailableNot Availablerecruiting
NCT06369207
Investigation of the Transmission Pathways of Reflux in Patients With Chronic Venous InsufficiencyNo drug interventionsNot AvailableNot Availablecompleted
NCT02395302
Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers (VLUs)No drug interventionstreatmentNot Availablecompleted
NCT04006184
Retrospective Review of Saphenous Vein Incompetence: Venaseal Versus Endovenous Thermal AblationNo drug interventionsNot AvailableNot Availablecompleted
NCT01972633
Endoluminale Obliteration Der Stammvene Mit Dem 1470nm Laser Versus VNUS Closure FastNo drug interventionstreatment1 / 2unknown_status
NCT02280733
A Real World, Observational Registry of Chronic Wounds and UlcersNo drug interventionsNot AvailableNot Availablerecruiting
NCT02061254
Transient Elastography DEdicated to Cosmetology And Dermatology (TEDECAD)No drug interventionsdiagnosticNot Availablecompleted
NCT01346553
Safety and Efficacy of the External Synchronized Vein Valve (ESVV) in Treatment of Chronic Venous Insufficiency (CVI)No drug interventionstreatmentNot Availableunknown_status
NCT01367977
Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in LifeNo drug interventionsNot AvailableNot Availablecompleted
NCT05633277
Outcomes of Sclerotherapy of the Ulcer Bed Compared to a Combination of Ablation and InjectionsNo drug interventionstreatmentNot Availablerecruiting
NCT01079598
RFS (Radiofrequency Stylet) - Radiofrequency Perforator Vein Treatment StudyNo drug interventionstreatmentNot Availableterminated
NCT04469361
The Effect of Training on Hemodynamic Factors in Ballet DancerNo drug interventionsNot AvailableNot Availablecompleted
NCT02588911
Radiofrequency Ablation vs Conventional Surgery for Superficial Venous InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT04524793
Efficacy and Safety of Endovenous Microwave Ablations for Treatment of Varicose Veins in SingaporeNo drug interventionstreatmentNot Availableunknown_status
NCT02241707
Does Minimal Post-operative Compression Affect the Outcome for Endovenous Ablation in Treating Varicose Vein Patients?No drug interventionsNot AvailableNot Availablewithdrawn
NCT02114307
REVITIVE for the Treatment of Patients With Venous InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT01680809
Compliance of Compression Therapy in Healed Venous UlcerationsNo drug interventionspreventionNot Availablewithdrawn
NCT02929056
Amniotic Membrane Allograft Application in the Management of Venous Leg UlcerationsNo drug interventionstreatment4terminated
NCT02626156
Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer RecurrenceNo drug interventionstreatment2completed
NCT04461132
The Effect of Manual Lymphatic DrainageNo drug interventionstreatmentNot Availablecompleted
NCT02621632
SocknLeg - a User Friendly Medical Compression Study of a Modified Application of a Medical DeviceNo drug interventionsprevention4completed
NCT00838500
THERMES ET VEINES: Spa for Prevention of Leg UlcersNo drug interventionstreatment3completed
NCT03283800
Copper Impact on Venous Insufficiency and LipodermatosclerosisNo drug interventionssupportive_careNot Availablecompleted
NCT02431819
Evaluation of the Safety of Compressive Socks to Treat Venous Insufficiency in Patients With Peripheral Arterial DiseaseNo drug interventionssupportive_careNot Availablecompleted
NCT00759434
A New Method of Surgically Treating Varicose Veins and Venous Ulcers - a Study to Assess Clinical and Economic ValueNo drug interventionstreatmentNot Availablecompleted
NCT03850496
DESIVI: Dosing of Electrical Stimulation in Venous InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT02191163
Efficacy of Antistax® in Improving Microcirculation of the Skin in the Leg in Patients Suffering From Chronic Venous InsufficiencyNo drug interventionstreatment2completed
NCT02397226
Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open SurgeryNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00013273
Physical Conditioning in Management of Chronic Venous InsufficiencyNo drug interventionstreatment2completed
NCT02498327
The Efficacy of Venavine Intensive® on the Quality of Life in Females With Chronic Venous InsufficiencyNo drug interventionsNot Available2completed
NCT01371760
BRAVE-DREAMS (BRAin VEnous DRainage Exploited Against Multiple Sclerosis)No drug interventionstreatmentNot Availablecompleted
NCT01549860
Effects of Non Contact Low Frequency Ultrasound in Healing Venous Leg UlcersNo drug interventionstreatmentNot Availablecompleted
NCT01793194
Preventing the Development of Venous Insufficiency in Pregnant Women Through Use of Compression StockingsNo drug interventionspreventionNot Availablecompleted
NCT00670540
Epidemiology of Thromboembolism Disease: A Cohort StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00565604
Safety and Efficacy of Endovenous Laser Ablation for the Resolution of Incompetent Perforator VeinsNo drug interventionstreatmentNot Availablecompleted
NCT03311269
A Study Evaluating ClariVein With a Sclerosing Agent for the Treatment of Venous Insufficiencytreatment2terminated
NCT05707169
Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose VeintreatmentNot Availableactive_not_recruiting
NCT05507346
A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity LymphedemaNo drug interventionstreatmentNot Availablecompleted
NCT01110512
Comparative Efficacy of Two Preparations of the Association Diosmin (450 mg) + Hesperidin (50 mg) in the Treatment of Chronic Venous Insufficiency (CVI)No drug interventionstreatment3unknown_status
NCT01458795
The Fate Of Calf Perforators After Endovenous Laser Ablation Of Saphenous VeinsNo drug interventionstreatment4completed
NCT04546750
Prospective Cohort Study for Varicose Veins Incidence and Natural CourseNo drug interventionsNot AvailableNot Availablerecruiting
NCT00732823
Compression Device Safety StudyNo drug interventionsbasic_science2completed
NCT01298908
Comparison of Treatments in Venous InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT00196443
The Influence of Compression Stockings on Skin's Barrier Function at Patients With Chronic Venous DiseaseNo drug interventionstreatment2 / 3completed
NCT00348764
ESGVS: Sclerotherapy With LauromacrogolNo drug interventionstreatment3completed
NCT01646502
Treatment of Chronic Wound BiofilmstreatmentNot Availablewithdrawn
NCT00855179
Assess the Efficacy and Tolerability of Antistax Film-coated Tablets in Patients With Chronic Venous InsufficiencyNo drug interventionstreatment3completed
NCT04215133
Inspiratory Muscle Training Versus Calf Muscle on Venous FunctionNo drug interventionstreatmentNot Availableunknown_status
NCT02191254
Efficacy and Tolerability of Antistax® in Male and Female Patients Suffering From Chronic Venous InsufficiencyNo drug interventionstreatment3completed
NCT03250247
Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)No drug interventionstreatmentNot Availablerecruiting
NCT02211898
Clinical Study of BNS003 on Swelling in Legs Due to Venous RefluxNo drug interventionstreatment3completed
NCT00762697
Obtaining and Storing Blood Samples and Debridement Samples for Wound Related ResearchNo drug interventionsNot AvailableNot Availablecompleted
NCT01701661
Compression Therapy Versus Surgery in the Treatment of Superficial Venous RefluxNo drug interventionstreatmentNot Availablecompleted
NCT00841178
Endovenous Laser Therapy (EVLT) for Sapheno-Popliteal Incompetence and Short Saphenous Vein (SSV) Reflux: A RCTNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00950378
Non-Invasive Management of Chronic Venous InsufficiencyNo drug interventionsNot AvailableNot Availablecompleted
NCT02729688
Effectiveness of a Pressure Indicator Guided and a Conventional Bandaging in Treatment of Venous Leg UlcerNo drug interventionstreatmentNot Availablecompleted
NCT00310752
Evaluation of DermStream(tm) - an Irrigation Product for Chronic Wound ManagementNo drug interventionstreatment1 / 2completed
NCT02137499
Venous Insufficiency and Neuromuscular StimulationNo drug interventionstreatmentNot Availablecompleted
NCT01509599
Cooling Lower Leg Skin to Prevent Venous Leg Ulcers in Patients With Poor Vein CirculationNo drug interventionsprevention1 / 2completed
NCT01173419
Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous VeinNo drug interventionstreatmentNot Availablewithdrawn
NCT02184234
Tolerability of Antistax® in Patients Suffering From Chronic Venous Insufficiency (CVI)No drug interventionstreatment4completed
NCT01558024
The Effects of Compression Stockings on Pressure Parameters in Patients With Chronic Venous InsufficiencyNo drug interventionsNot AvailableNot Availablecompleted
NCT00292435
Efficacy and Tolerability CVI (A 12-week, Double-blind, Randomised, Placebo-controlled, Multicentre Trial (CVI)No drug interventionsNot Available3completed
NCT02051439
The Party Balloon Assisted Valsalva in Diagnosis of Superficial Venous Valvular Reflux of Lower LimbNo drug interventionsdiagnosticNot Availablecompleted
NCT00720239
Taliderm Dressing for Venous UlcersNo drug interventionstreatment0completed
NCT01415622
Feasibility, Efficacy, and Safety of Venous Ulcer Treatment Using a Hand Plasma Generator (PlasmaDerm) Chronisch venöser Ulzerationen (PlasmaDerm)No drug interventionstreatmentNot Availablecompleted
NCT00835822
Efficacy and Safety of the Use of Venocur Triplex® in Patients With Chronic Venous InsufficiencyNo drug interventionstreatment4completed
NCT00617825
Feasibility Study of Cryotherapy for Chronic Venous DisordersNo drug interventionstreatmentNot Availablecompleted
NCT03652025
The Effectiveness of Trans-catheter Foam Sclerotherapy of Pelvic and Atypical Lower Limb VaricositiesNo drug interventionstreatmentNot Availableunknown_status
NCT00858130
Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome (PTS)No drug interventionstreatmentNot Availablecompleted
NCT02689557
VEINEX : Venous Investigations During ExerciseNo drug interventionsdiagnosticNot Availablecompleted
NCT00395265
Evaluating the Relationship Between Blood Clotting Disorders, Inflammation, and Obesity in Individuals With Venous Disorders and Post-Thrombotic SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT02483962
Venavine Intensive® in the Treatment of Symptoms Associated With Chronic Venous InsufficiencyNo drug interventionstreatment2completed
NCT02191280
Antistax® in Patients With Chronic Venous InsufficiencyNo drug interventionstreatment2completed
NCT03755180
Exercise Training in Venous InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT02324504
Evaluation of Electrocardiographic Guidance in Accurate Peripherally Inserted Central Catheter Placement in Children.No drug interventionstreatmentNot Availablecompleted
NCT00270972
The Evaluation of OrCel for the Treatment of Venous UlcersNo drug interventionstreatmentNot Availableunknown_status
NCT03471910
Clinical Non-inferiority Study Between Diosmin 600mg & Diosmin + Hesperidin in Symptomatic Chronic Venous Insufficiencytreatment4completed
NCT03543007
Evaluating the Safety and Efficacy of GrafixPL™PRIME for the Treatment of Chronic Venous Leg UlcersNo drug interventionstreatmentNot Availablenot_yet_recruiting