Adrenomyeloneuropathy (DBCOND0037996)

Identifiers

Synonyms

Adrenomyeloneuropathy (disorder) / X-linked adrenoleukodystrophy, unspecified type / X-linked adrenoleukodystrophy / Adrenoleukodystrophy / Adrenoleukodystrophy (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT02961803	MD1003-AMN MD1003 in Adrenomyeloneuropathy	Biotin	treatment	2 / 3	completed
NCT02699190	LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT05146284	Study to Assess PXL770 in Subjects With Adrenomyeloneuropathy (AMN) Form of X-linked Adrenoleukodystrophy (X-ALD or ALD)	No drug interventions	treatment	2	not_yet_recruiting
NCT05443906	Home Exercise for Individuals With Neurodegenerative Disease	No drug interventions	treatment	Not Available	recruiting
NCT04925349	Modeling Macrophages Activation Pattern in X-linked Adrenoleukodystrophy, Metachromatic Leukodystrophy and Adult Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia	No drug interventions	Not Available	Not Available	recruiting
NCT04303416	Plasma Exchange With Albumin in AMN Patients	Albumin human	treatment	2 / 3	completed
NCT01495260	A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants	Acetylcysteine Lipoic acid Vitamin E	treatment	2	completed
NCT03047369	The Myelin Disorders Biorepository Project	No drug interventions	Not Available	Not Available	recruiting
NCT03864523	Effect of Pioglitazone Administered to Patients With Adrenomyeloneuropathy	Pioglitazone	treatment	2	completed
NCT00545597	A Phase III Trial of Lorenzo's Oil in Adrenomyeloneuropathy	No drug interventions	treatment	3	terminated
NCT01787578	Safety and Pharmacodynamic Study of Sobetirome in X-Linked Adrenoleukodystrophy (X-ALD)	Sobetirome	treatment	1	withdrawn
NCT03627416	Repetitive Transcranial Magnetic Stimulation as Therapy in Hereditary Spastic Paraplegia and Adrenomyeloneuropathy	No drug interventions	treatment	Not Available	completed
NCT01165060	The Effect of Bezafibrate on the Level of Very Long Chain Fatty Acids (VLCFA) in X-linked Adrenoleukodystrophy (X-ALD)	Bezafibrate	treatment	Not Available	completed