Small Cell Lung Cancer (SCLC) (DBCOND0048944)

Identifiers

Synonyms
Small Cell Lung Carcinoma (SCLC) / Small Cell Carcinoma of Lung / Small Cell Lung Cancer, SCLC / Cancer - Small Cell Lung Cancer / Small-Cell Lung Cancer (SCLC) / Small Cell Lung Cancer SCLC / Small Cell Lung Carcinoma / Carcinoma, Small-Cell Lung / Lung Small Cell Carcinoma / Carcinoma, Small Cell Lung / Small Cell Lung Cancer / Lung Cancer, Small Cell / Small-Cell-Lung Cancer / Small- Cell Lung Cancer / Lung Cancer Small Cell Lung Cancer (SCLC) / Small Cell Carcinoma of the Lung / Small Cell Lung Cancer ( SCLC ) / SCLC / Small Cell Lung Cancers / Small-Cell Lung Cancer / Small cell lung cancer progression / Oat cell carcinoma of lung (disorder) / Small cell lung cancer stage unspecified / Small cell carcinoma of lung (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Atezolizumab
A monoclonal antibody used to treat advanced or metastatic urothelial carcinoma with disease progression during or up to 12 months after platinum-containing chemotherapy.
Docetaxel
A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
Epirubicin
An anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer.
Etoposide
A podophyllotoxin derivative used to treat testicular and small cell lung tumors.
Gemcitabine
A nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
Ifosfamide
An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
Irinotecan
A topoisomerase inhibitor used to treat metastatic carcinoma of the colon or rectum and pancreatic adenocarcinoma.
Vincristine
A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05990738
DAREONTM-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent Chemotherapytreatment1recruiting
NCT06077500
DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancertreatment1recruiting
NCT05879978
A Study to Test How Well Different Doses of BI 764532 in Combination With Ezabenlimab Are Tolerated by People With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3treatment1 / 2recruiting
NCT05963867
A Study to Test How BI 764532 is Taken up by Tumours in People With Small-cell Lung Cancer or Neuroendocrine CancerNo drug interventionstreatment1recruiting
NCT01635400
Study of Relationship Between UGT1A1 Gene Polymorphism and Toxicity and Efficacy of Irinotecan in Small Cell Lung Cancertreatment2unknown_status
NCT05490472
JAB-2485 Activity in Adult Patients With Advanced Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT04180176
Prospective Clinicogenomic ProgramNo drug interventionsother4completed
NCT03505515
Treatment Patterns, Clinical Outcomes, and Healthcare Resource Utilization Associated With Chinese Patients With Advanced Lung CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT03227016
Study in Patients With SCLC of Veliparib in Combination With Topotecantreatment1unknown_status
NCT05616624
ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancerstreatment1 / 2recruiting
NCT06131840
A Study of PF-08046050 (SGN-CEACAM5C) in Adults With Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT06247163
PET-guided Radiotherapy for Patients With Small Cell Lung Cancer.No drug interventionsNot AvailableNot Availablerecruiting
NCT06264921
A Study with NKT3447 for Adults with Advanced/Metastatic Solid TumorsNo drug interventionstreatment1recruiting
NCT06586957
A Study with NKT3964 for Adults with Advanced/Metastatic Solid TumorsNo drug interventionstreatment1not_yet_recruiting
NCT06558903
Searching for Predictive Biomarkers of Efficacy in Small Cell Lung Cancer Patients Treated With Chemotherapy-immunotherapy Combination Using Imaging Mass Cytometry (HYPE)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02874664
A Study of Rovalpituzumab Tesirine to Study Cardiac Ventricular Repolarization in Subjects With Small Cell Lung Cancertreatment1completed
NCT02763579
A Study of Carboplatin Plus Etoposide With or Without Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)treatment3completed
NCT01286987
Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumorstreatment1completed
NCT00423254
Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.No drug interventionstreatment1completed
NCT05945745
Molecular Analysis and Treatment Options of SCLCNo drug interventionsNot AvailableNot Availablerecruiting
NCT01540045
Effect of Chemotherapy With Paclitaxel/Cisplatin on Development Dysgeusia in Non Small Cell Lung CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT00445198
A Phase 1/2a Study of ABT-263 in Subjects With Small Cell Lung Cancer (SCLC) or Other Non-Hematological Malignanciestreatment1 / 2completed
NCT06247605
A Phase IIII Study of AL8326 in Small Cell Lung CancerNo drug interventionstreatment3recruiting
NCT03568097
Immunotherapy in Combination With Chemotherapy in Small-cell Lung Cancertreatment2active_not_recruiting
NCT03512015
A Mobile Supportive Care App for Patients With Metastatic Lung CancerNo drug interventionssupportive_careNot Availableunknown_status
NCT01187615
Determination of Safety, Efficacy, and Pharmacokinetics of "Regorafenib" Combined With Pemetrexed and Cisplatin in Patients With Nonsquamous Non-Small Cell Lung Cancertreatment1terminated
NCT01574300
Collaborative Advanced Stage Tissue Lung Cancer (CASTLE) NetworkNo drug interventionsNot AvailableNot Availableterminated
NCT00927875
A Study of BMS-833923 With Carboplatin and Etoposide Followed by BMS-833923 Alone in Subjects With Extensive-Stage Small Cell Lung Cancertreatment1completed
NCT01441349
Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancertreatment2unknown_status
NCT01222936
LBH Phase II in Small Cell Lung Cancer (SCLC)treatment2completed
NCT06481813
Prospective, Longitudinal Biocollection in Thoracic Oncology, Including Newly Diagnosed Lung Cancer PatientsNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT04507919
Managed Access Program Cohort Treatment Plan CTMT212X2002I to Provide Access to Trametinib and Dabrafenib Combination Therapy for Patients With BRAF V600 Mutation-positive Advanced Non-Small Cell Lung CancerNot AvailableNot Availableavailable
NCT04199741
PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56No drug interventionsNot AvailableNot Availablerecruiting
NCT04938817
Safety and Efficacy Study of Pembrolizumab (MK-3475) in Combination With Investigational Agents for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)treatment1 / 2active_not_recruiting
NCT01941316
Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patientstreatment1 / 2completed
NCT01553916
Neuroprotective Effects of Lithium in Patients With Small Cell Lung Cancer Undergoing Radiation Therapy to the Brainsupportive_care1 / 2completed
NCT05882058
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine CancersNo drug interventionstreatment2recruiting
NCT01977235
Two Different Dosages of Irinotecan Combined With Cisplatin Scheme in Extensive Disease-Small Cell Lung Cancertreatment2unknown_status
NCT06177925
A Phase Ⅱ Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLCtreatment2recruiting
NCT04173325
Feasibility and Safety Study of Nivolumab With Irinotecan for Small Cell Lung Cancertreatment1terminated
NCT02394548
Phase I Trial Of IMRT Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Lung CancerNo drug interventionstreatmentNot Availablecompleted
NCT03662074
Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancertreatment2terminated
NCT05582031
Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancerstreatment2withdrawn
NCT05419076
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the BrainNo drug interventionstreatment2recruiting
NCT06501976
An Exploratory Study of Lurbinectedin With Radiotherapy in Locally-advanced SCLC After First-line Therapytreatment2not_yet_recruiting
NCT03532880
A Study of Olaparib and Low Dose Radiotherapy for Small Cell Lung Cancertreatment1active_not_recruiting
NCT01722292
A Study of LY2940680 in Small Cell Lung Cancertreatment1 / 2terminated
NCT00926640
A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancerstreatment1completed
NCT02628067
Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)treatment2recruiting
NCT03850067
A Safety, Tolerability and Preliminary Efficacy Evaluation of CC-90011 Given in Combination With Cisplatin and Etoposide in Subjects With First Line, Extensive Stage Small Cell Lung Cancertreatment1completed
NCT02876081
Phase II Study of Afatinib as Third- or Further-line Treatment for Patients With Stage IV Bronchial Adenocarcinoma, Harboring Wild-type EGFR, Expressing the Neurotensin - Neurotensin Receptor Complextreatment2withdrawn
NCT03735095
Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancertreatment1 / 2active_not_recruiting
NCT02487095
Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancerstreatment1 / 2active_not_recruiting
NCT02658214
Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumorstreatment1completed
NCT04363255
First-line Chemotherapy Followed by Toripalimab Combined With Anlotinib for Maintenance in ES-SCLCtreatment2unknown_status
NCT00143455
Study Of Irinotecan Hydrochloride (Campto(R)) And Cisplatin Versus Etoposide And Cisplatin In Small Cell Lung Cancertreatment3completed
NCT00299390
Safety and Efficacy Study of a New Chemotherapy Agent to Treat Small Cell Lung Cancertreatment2terminated
NCT02937402
Bronchoscopy With Bronchoalveolar Lavage in Identifying Biomarkers of Response to Immune Checkpoint Inhibitors in Patients With Non-small Cell or Small Cell Lung CancerNo drug interventionsdiagnosticNot Availableterminated
NCT06419179
Maintenance Durvalumab (MEDI4736) and Olaparib (AZD2281) After Standard 1st Line Treatment (Carboplatin/Cisplatin, Etoposide, Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC)treatment2not_yet_recruiting
NCT02397733
Memory Preservation of Prophylactic Cranial Irradiation With Hippocampal Avoidance (PREMER-TRIAL)No drug interventionspreventionNot Availablecompleted
NCT04901754
Camrelizumab Plus Apatinib as Maintenance Therapy in Extensive-stage Small-cell Lung Cancertreatment2unknown_status
NCT01317953
Oral Green Tea Extract for Small Cell Lung CancerNo drug interventionsNot AvailableNot Availableavailable
NCT05683977
A French Real-life Study: EvaluatioN of durvALumab Utilization and Effectiveness for First Line Extensive Stage Small Cell Lung Cancer.Not AvailableNot Availableactive_not_recruiting
NCT02041845
Two Schedules of Hyperfractionated Thoracic Radiotherapy in Limited Disease Small Cell Lung CancerNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05703997
FASTing-like Approach and Maintenance IMMunotherapy in ES-SCLC Patients Not Progressing on Chemoimmunotherapy Inductiontreatment2not_yet_recruiting
NCT06236997
Adebrelimab and Concurrent Radiochemotherapy as First-line Treatment for Extensive-stage Small-cell Lung Cancertreatment2not_yet_recruiting
NCT01450761
Trial in Extensive-Disease Small Cell Lung Cancer (ED-SCLC) Subjects Comparing Ipilimumab Plus Etoposide and Platinum Therapy to Etoposide and Platinum Therapy Alonetreatment3completed
NCT00977561
A Study Of Cisplatin (Or Carboplatin) And Etoposide With Or Without Figitumumab (CP-751,871) In Patients With Extensive-Stage Small Cell Lung Cancertreatment2terminated
NCT04672928
A Phase Ib/III Clinical Study to Evaluate the Efficacy and Safety of IBI318 in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel in Patients With Small Cell Lung Cancer Who Have Failed First-line or Above Chemotherapiestreatment1completed
NCT03232593
A Study of Atezolizumab (Tecentriq®) in Ministry of Food and Drug Safety (MFDS)-Approved Indication(s)Not AvailableNot Availablecompleted
NCT04996771
Surufatinib Combined With Chemotherapy Plus Toripalimab or Not in the Treatment of Small Cell Lung Cancertreatment1 / 2recruiting
NCT03517488
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumorstreatment1completed
NCT04665856
Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung Cancertreatment3active_not_recruiting
NCT04620837
Tislelizumab in Combination With Anlotinib With ES-SCLC as Maintenance Therapy After First Line Chemotherapytreatment2unknown_status
NCT04358237
Lurbinectedin (PM01183) Combined With Pembrolizumab in Small Cell Lung Cancer.treatment1 / 2active_not_recruiting
NCT02062632
Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapysupportive_care2terminated
NCT03221400
PEN-866 in Patients With Advanced Solid Malignanciestreatment1 / 2unknown_status
NCT03700359
A Study of Lobaplatin/Etoposide With or Without Anlotinib Maintenance Therapy in Patients With ES-SCLCtreatment2unknown_status
NCT05620342
Autologous CAR T-Cells Targeting the GD2 Antigen for Lung CancerNo drug interventionstreatment0recruiting
NCT02161419
RONICICLIB / Placebo in Combination With Chemotherapy in Small Cell Lung Cancertreatment2terminated
NCT05224141
Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008, KEYVIBE-008)treatment3active_not_recruiting
NCT03092934
A Study of AK-01 (LY3295668) in Solid Tumorstreatment1 / 2completed
NCT00759824
A Phase II Study of Doxorubicin, Cyclophosphamide and Vindesine With Valproic Acid in Patients With Refractory or Relapsing Small Cell Lung Cancer After Platinum Derivatives and Etoposidetreatment2completed
NCT05049863
Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)treatment1 / 2recruiting
NCT05617963
Durvalumab Maintenance After Thoracic Chemoradiotherapy in Frail Small Cell Lung Cancer Patients Whose Disease is Limited to the Thoraxtreatment2recruiting
NCT04453930
A Study of Sequential Therapy of Camrelizumab Combined With Chemotherapy(Irinotecan Plus Platinum)and With Apatinib in Participants With Untreated Advanced Small Cell Lung Cancer(SCLC)treatment2unknown_status
NCT05450965
Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancertreatment2active_not_recruiting
NCT05265429
Biology of Young Lung Cancer Study: The YOUNG LUNG StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03994744
Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLCtreatment2unknown_status
NCT03319940
Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC)treatment1active_not_recruiting
NCT05027867
KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancertreatment2terminated
NCT04902872
Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid TumorsNo drug interventionstreatment1 / 2active_not_recruiting
NCT03849469
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumorstreatment1completed
NCT03509012
Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumorstreatment1active_not_recruiting
NCT06529081
Radiotherapy Strategies for Use in Combined Treatment of Small-cell Lung CancerNo drug interventionstreatment2recruiting
NCT01357395
A Phase 2, Open-Label Study of Amuvatinib in Combination With Platinum-Etoposide Chemotherapy in Small Cell Lung Cancertreatment2completed
NCT03963414
A Study of Durvalumab Plus Tremelimumab With Chemotherapy in Untreated ES-SCLCtreatment1terminated
NCT04028050
A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung Cancertreatment3completed
NCT05329623
A Phase 1 Study to Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants.No drug interventionstreatment1recruiting
NCT01573338
Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 When Given Together With Chemotherapy and the Effectiveness of This Combination Treatment in Shrinking a Specific Type of Lung Tumors (Small Cell Lung Cancer)treatment1 / 2terminated
NCT01306045
Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignanciestreatment2completed
NCT00923884
Prospective Analysis of Genotypes in Adults Undergoing Therapy for Lung CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT04985357
Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to DrugsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04622228
Study of Low-Dose Radiotherapy (LDRT) Concurrent Cisplatin/Carboplatin Plus Etoposide With Atezolizumab for Patients With Extensive-Stage Small Cell Lung Cancertreatment2completed
NCT03871205
Neoantigen-primed DC Vaccines Therapy for Refractory Lung CancerNo drug interventionstreatment1unknown_status
NCT03699956
RRx-001 Sequentially With a Platinum Doublet or a Platinum Doublet in Third-Line or Beyond in Patients With Small Cell Lung Cancertreatment3terminated
NCT04308785
A Study of Atezolizumab With or Without Tiragolumab Consolidation in Limited Stage Small Cell Lung Cancertreatment2terminated
NCT00435578
Safety and Efficacy Study of Glufosfamide in Patients With Recurrent Sensitive Small Cell Lung Carcinomatreatment2terminated
NCT00037713
Survival in a Randomized Phase III Trial in Patients With Limited Disease (LD) Small Cell Lung Cancer Vaccinated With Adjuvant BEC2 and BCGNo drug interventionstreatment3completed
NCT04253145
Study to Assess Safety,Tolerability,Efficacy of PM01183 and Atezolizumab in Patients w/ Advanced Small Cell Lung Cancer.treatment1 / 2recruiting
NCT02936323
PEN-221 in Somatostatin Receptor 2 Expressing Advanced Cancers Including Neuroendocrine and Small Cell Lung Cancerstreatment1 / 2completed
NCT00294931
Irinotecan, Carboplatin, Bevacizumab in the Treatment of Patients With Extensive Stage Small Cell Lung Cancertreatment2completed
NCT00270166
The Effect of Epoetin Alfa on the Anemia of Patients With Selected Cancers Receiving Chemotherapytreatment3completed
NCT00265200
Using TRAP to Evaluate the Effect of Zometa on Bone Metastasis Due to Lung Cancerdiagnostic2terminated
NCT05566041
A Phase 3, Controlled, Open-label, Global Randomized Study of RRx-001 With a Platinum Doublet or a Platinum Doublet in Small Cell Lung Cancertreatment3recruiting
NCT03083691
BIOLUMA: Biomarkers for Nivolumab and Ipilimumab and Evaluation of the Combination in Lung Cancertreatment2completed
NCT02736916
HS-WBRT for Prophylactic Cranial Irradiation in Limited Stage Small Cell Lung CancerNo drug interventionstreatmentNot Availableunknown_status
NCT00637624
N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing ChemotherapypreventionNot Availableterminated
NCT00308529
Irinotecan, Carboplatin, Bevacizumab, and Radiation Therapy in the Treatment of Limited Stage Small Cell Lung Cancertreatment2completed
NCT00263731
Metabolomic Analysis of Lung CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT01284348
To Determine Safe and Effective Dose of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Participants With Advanced Non-small Cell Lung Cancersupportive_care2terminated
NCT05557708
A Safety Study of 212Pb-Pentixather Radioligand TherapyNo drug interventionstreatment0not_yet_recruiting
NCT04314401
National Cancer Institute "Cancer Moonshot Biobank"No drug interventionsNot AvailableNot Availablerecruiting
NCT05304793
Testing a Cognitive Behavioral Model for Reducing Dyspnea in Patients With Lung CancerNo drug interventionssupportive_careNot Availablecompleted
NCT06438588
Fasting Mimicking Diet for Reducing Immune Related Adverse Events for Cancer Patients on Immune Checkpoint Inhibitors, FMD-ICI TrialNo drug interventionssupportive_careNot Availablerecruiting
NCT04701307
Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomastreatment2active_not_recruiting
NCT04155034
S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung CancerNo drug interventionstreatment3recruiting
NCT04242199
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT02146170
Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial TumorsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02769962
Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancertreatment1 / 2recruiting
NCT03554473
M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancerstreatment1 / 2recruiting
NCT06095505
A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancertreatment2recruiting
NCT06117774
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)treatment3recruiting
NCT06203210
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancertreatment3recruiting
NCT04951947
JS-201 Combined With Lenvatinib in the Treatment of Small-cell Lung Cancertreatment2recruiting
NCT04768296
Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)treatment2completed
NCT05552846
Phase II Trial of Consolidative Thoracic Radiotherapy for ES-SCLC After Standard Care of Chemo-immunotherapyNo drug interventionstreatmentNot Availablerecruiting
NCT05551117
A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumorstreatment2active_not_recruiting
NCT05620134
Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancertreatment1 / 2recruiting
NCT05703269
Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving ImmunotherapyNo drug interventionssupportive_careNot Availablerecruiting
NCT06211036
Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumabtreatment3recruiting
NCT06449209
Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With ChemotherapyNo drug interventionstreatment2recruiting
NCT06497543
Intrathecal Pemetrexed for SCLC Patients With Refractory Brain Metastases or Leptomeninges Metastatictreatment2not_yet_recruiting
NCT06527898
Hypofractionated Radiotherapy Combined with Immunotherapy for Limited-stage Small-cell Lung CancerNo drug interventionstreatment1 / 2recruiting
NCT05783622
Study of JANX008 in Subjects with Advanced or Metastatic Solid Tumor MalignanciesNo drug interventionstreatment1recruiting
NCT05903092
MOnaliZumab in Combination With durvAlumab (MEDI4736) Plus Platinum-based chemotheRapy for First-line Treatment of Extensive Stage Small Cell Lung Cancertreatment2recruiting
NCT06064500
Tarlatamab (AMG 757) Expanded Access Protocol for Advanced Small Cell Lung CancerNot AvailableNot Availableavailable
NCT06612151
A Phase III Study to Evaluate the Efficacy and Safety of YL201 in Relapsed Small Cell Lung Cancertreatment3not_yet_recruiting
NCT06592638
A Phase 1 Dose Escalation Study of ZG006 in Patients with Small Cell Lung CancerNo drug interventionstreatment1not_yet_recruiting
NCT04450043
The Transitions Project: Supporting Adults During the Shift From Cancer Treatment to SurveillanceNo drug interventionssupportive_careNot Availableunknown_status
NCT00403403
A Study of Bevacizumab in Previously Untreated Extensive-Stage Small Cell Lung Cancer (SALUTE)treatment2completed
NCT02963090
Pembrolizumab vs Topotecan in Patients With Small Cell Lung Cancertreatment2terminated
NCT00294190
Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung Cancertreatment2completed
NCT06480864
Adebrelimab Plus Apatinib for Maintenance Therapy of Extensive Small Cell Lung CancertreatmentNot Availablenot_yet_recruiting
NCT01045421
Alisertib in Adults With Nonhematological Malignancies, Followed by Alisertib in Lung, Breast, Head and Neck or Gastroesophageal Malignanciestreatment1 / 2completed
NCT04490421
Camrelizumab Combined With Apatinib, Etoposide and Cisplatin Treat Small-cell Lung Cancer.treatment3unknown_status
NCT05978284
Study of ZG006 in Participants With Small Cell Lung Cancer or Neuroendocrine CarcinomaNo drug interventionstreatment1 / 2recruiting
NCT06483919
The Predictive Value of Proteome Profiling for Brain Metastasis in Limited-Stage Small-Cell Lung CancerNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06255197
Characteristics, Treatment Patterns and Outcomes for Patients With Surgically Resected Lung CancersNo drug interventionsNot AvailableNot Availablerecruiting
NCT06242470
A Study of MGC026 in Participants With Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT05285033
RW Effectiveness of Lurbinectedin in Extensive Stage SCLCNot AvailableNot Availablecompleted
NCT06160596
Analyzing and Solving Exceptional Long-term Survivors in Solid Tumors With Poor PrognosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT04742959
Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumorstreatment1 / 2completed
NCT04672759
A Real-world Study of Durvalumab for Lung Cancer in ChinaNot AvailableNot Availablerecruiting
NCT04610658
Immune Checkpoint Inhibition With Lurbinectedin Relapsed/Recurrent SCLCtreatment1terminated
NCT04539977
PD-L1 Antibody (TQB2450) Plus Chemotherapy for Previously Untreated Limited- Stage Small-cell Lung Cancertreatment2recruiting
NCT04535739
PCI for Patients With ES-SCLC After RCT:a Prospective Randomized StudyNo drug interventionstreatment3unknown_status
NCT04500145
Simultaneous Integrated Boost vs. Routine IMRT in Limited-stage Small-cell Lung CancerNo drug interventionstreatment3unknown_status
NCT04152499
Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapiestreatment1 / 2recruiting
NCT03923270
Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancertreatment1active_not_recruiting
NCT03728361
Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancertreatment2active_not_recruiting
NCT03613597
Etoposide Plus Lobaplatin Versus Etoposide Plus Cisplatin for Patients With Limited Small-cell Lung Cancertreatment2unknown_status
NCT05420636
Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NETtreatment2recruiting
NCT03345485
Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumorstreatment1 / 2completed
NCT02058056
Early Hippocampal Avoidance Prophylactic Cranial Irradiation in Patients With LD SCLCNo drug interventionstreatmentNot Availablecompleted
NCT01797159
Hippocampal Prophylactic Cranial Irradiation for Small Cell Lung CancerNo drug interventionstreatmentNot Availablecompleted
NCT04060342
GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinomatreatment1terminated
NCT03389087
Study of Apatinib Plus Etoposide Capsule as the Therapy of Advanced Small Cell Lung Cancertreatment2unknown_status
NCT02297087
Next-generation Sequencing of Small Cell Lung Cancer to Identify Actionable Targets for TreatmentNo drug interventionsdiagnosticNot Availableterminated
NCT02995187
Study of Apatinib as Third-line and Later Therapy in Patients With Small Cell Lung Cancer (SCLC)treatment2unknown_status
NCT00316433
Oxaliplatin/CPT-11 for Extensive Stage Small Cell Lung Cancertreatment2terminated
NCT00791154
QUILT-2.013: First-Line Treatment for Extensive Stage Small Cell Lung Cancertreatment1 / 2terminated
NCT05257551
Tempus Sculptor Study: Small Cell Lung Cancer (SCLC) Observational StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04332653
NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumorstreatment1 / 2active_not_recruiting
NCT03724253
[68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR)No drug interventionsdiagnostic2terminated
NCT03652077
A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignanciestreatment1completed
NCT02038647
Phase 2 Study of Alisertib (MLN8237) in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel as Second Line Therapy for Small Cell Lung Cancer (SCLC)treatment2completed
NCT01640847
MRI Guided High Intensity Focused Ultrasound (HIFU) and ThermoDox for Palliation of Painful Bone Metastasestreatment2withdrawn
NCT02514447
Trilaciclib (G1T28) in Patients With Previously Treated Extensive Stage SCLC Receiving Topotecan Chemotherapytreatment1 / 2terminated
NCT01745445
Clinical Randomized Study of Concurrent Chemo-radiotherapy vs Radiotherapy Alone to Local-advanced Small Cell Lung Cancer (SCLC)No drug interventionstreatment2unknown_status
NCT05673798
Development and Validation of Nomogram Predicting Survival in Chinese SCLC PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00178698
Hyperthermia/Thermal Therapy With Chemotherapy to Treat Inoperable or Metastatic Tumorstreatment2unknown_status
NCT03879798
DS-3201b and Irinotecan for Patients With Recurrent Small Cell Lung Cancertreatment1 / 2terminated
NCT06462105
Liposomal Irinotecan Combination Regimen for First-line Treatment of Small Cell Lung CancertreatmentNot Availablenot_yet_recruiting
NCT02261805
A Phase I/II Study of Ganetespib in Combination With Doxorubicintreatment1 / 2terminated
NCT01441297
BIBF 1120 as Second Line Treatment for Small Cell Lung Cancertreatment2completed
NCT03780283
Efficacy and Safety of Anlotinib as Maintenance Treatment After First-line Chemotherapy in SCLCtreatment2unknown_status
NCT01880528
Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung Cancersupportive_care2completed
NCT03041311
Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLCtreatment2terminated
NCT02605811
Temozolomide in Preventing Brain Metastases in Small Cell Lung Cancertreatment2unknown_status
NCT03033511
A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)treatment3terminated
NCT05001971
Anlotinib Plus Penpulimab for the Treatment of Sensitive Relapsed Small-Cell Lung Cancertreatment2unknown_status
NCT00472771
INNO-206 in Patients With Small Cell Lung Cancer (SCLC)treatment2withdrawn
NCT01943578
Value of Physical Capacity Tests in Lung CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT01237678
A Study of IMGN901 for Patients With Advanced Solid Tumors and Extensive Stage Small Cell Lung Cancertreatment1 / 2terminated
NCT03881488
Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignanciestreatment1active_not_recruiting
NCT05780307
IMM2520, a PD-L1 and CD47 Bispecific Antibody in Patients With Advanced Solid Tumorstreatment1recruiting
NCT01784107
A Phase Ib/II Trial of Belotecan and Ifosfamide in Patients With Extensive Disease of Small Cell Lung Cancertreatment1 / 2unknown_status
NCT00401609
G-Step: Gemcitabine Based Small-cell Lung Cancer Treatment in Elderly Patientstreatment1 / 2completed
NCT00617409
To Immunize Patients With Extensive Stage SCLC Combined With Chemo With or Without All Trans Retinoic Acidtreatment2completed
NCT05623956
Proteomics in Small Cell Lung CancerNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03406715
Combination Immunotherapy-Ipilimumab-Nivolumab-Dendritic Cell p53 Vac - Patients With Small Cell Lung Cancer (SCLC)treatment2terminated
NCT02542137
Abscopal Effect for Metastatic Small Cell Lung Cancertreatment2withdrawn
NCT02551432
Pembrolizumab and Paclitaxel in Refractory Small Cell Lung Cancertreatment2completed
NCT05983432
Study to Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid TumorsNo drug interventionstreatment1recruiting
NCT02223052
Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignanciestreatment1completed
NCT01631552
Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancertreatment1 / 2completed
NCT02661100
A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patientstreatment1 / 2withdrawn
NCT02152059
A Study to Evaluate the Good and Bad Effects of BIBF1120 in Small Cell Lung Cancer Patients Who Have Previously Benefited From First-line Platinum-based Chemotherapytreatment2withdrawn
NCT01486459
A Feasibility Trial Using Lithium As A Neuroprotective Agent In Patients Undergoing Prophylactic Cranial Irradiation For Small Cell Lung CancertreatmentNot Availableterminated
NCT02819999
A Study of Rovalpituzumab Tesirine (SC16LD6.5) in the Frontline Treatment of Patients With Extensive Stage Small Cell Lung Cancertreatment1terminated
NCT04730999
Efficacy and Safety Study of a New Therapeutic Strategy in the Treatment of Extended-Disease Small-Cell Lung Cancertreatment2completed
NCT03043599
Ipilimumab + Nivolumab w/Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancertreatment1 / 2completed
NCT00969306
Chloroquine as an Anti-Autophagy Drug in Stage IV Small Cell Lung Cancer (SCLC) Patientstreatment1terminated
NCT04012606
Toripalimab in Combination With Platinum Plus Etoposidein Patients With Extensive-Stage Small Cell Lung CancerNo drug interventionstreatment3unknown_status
NCT02247349
BMS-986012 in Relapsed/Refractory SCLCtreatment1 / 2completed
NCT02273336
Comprehensive Genomic Analysis in Tissue and Blood Samples From Young Patients With Lung CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT03734913
A Phase 1 Study of ZSP1602 in Participants With Advanced Solid TumorsNo drug interventionstreatment1unknown_status
NCT00119613
A Study of Subjects With Previously Untreated Extensive-Stage Small-Cell Lung Cancer (SCLC) Treated With Platinum Plus Etoposide Chemotherapy With or Without Darbepoetin Alfatreatment3completed
NCT04504513
Expanded Access to Trilaciclib for Patients Receiving Chemotherapy for Small Cell Lung CancerNot AvailableNot Availableapproved_for_marketing
NCT04352413
A Study of PLM60 in Subjects With Relapsed Small-cell Lung Cancer After Platinum-based First-Line ChemotherapyNo drug interventionstreatment2terminated
NCT01266018
Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancertreatment2terminated
NCT03651219
Mesylate Apatinib Combined With Irinotecan in Treatment of Recurrent Small Cell Lung Cancertreatment3unknown_status
NCT06283719
Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Advanced Small Cell Lung CancerNo drug interventionstreatment1 / 2not_yet_recruiting
NCT03904719
CM082 and JS001 in Patients With Advanced Small-cell Lung Cancer (SCLC)treatment2unknown_status
NCT02593019
Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patientstreatment2completed
NCT06505824
A Study of BL-M14D1 in Patients With Locally Advanced or Metastatic Small Cell Lung Cancer, Neuroendocrine Tumors and Other Solid TumorsNo drug interventionstreatment1recruiting
NCT01872416
A Clinical Study of Liposomal Doxorubicin Combined With Ifosfamide Second-line Treatment in Small Cell Lung CancerNo drug interventionstreatment2unknown_status
NCT02324296
PEI REGIMEN: A Therapeutic Option in Small Cell Lung Cancer? A Monoinstitutional Experience of 46 Consecutive CasesNot AvailableNot Availablecompleted
NCT01173458
Circulating Tumor Cells (CTCs) as a Blood-based Tumor Marker in Patients With Small Cell Lung Cancer (SCLC)No drug interventionsNot AvailableNot Availablecompleted
NCT05337163
A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in ChinaNo drug interventionsNot AvailableNot Availablecompleted
NCT00415363
Study of Enzastaurin Versus Placebo in the Treatment of Patients With Brain Metastases of Lung Cancer, After Whole Brain Radiation Therapytreatment2completed
NCT04171986
Mecapegfilgrastim Prevents Neutropenia and Radiation EsophagitispreventionNot Availableunknown_status
NCT00958022
Carboplatin and Etoposide Plus LBH589 for Small Cell Lung Cancertreatment1terminated
NCT04165330
Evaluation of AL3818 in Combination With Nivolumab in Solid Tumorstreatment1 / 2active_not_recruiting
NCT05882630
Surufatinib Combined With Serplulimab Plus Chemotherapy in the Treatment of Extensive-stage Small Cell Lung Cancertreatment1 / 2not_yet_recruiting
NCT02875457
Apatinib as the Maintenance Therapy for Extensive Stage Small Cell Lung Cancer After Combined With Etoposide/Cisplatintreatment3unknown_status
NCT00475657
Pemetrexed and Cisplatin as Treatment in Small Cell Lung Cancertreatment2terminated
NCT00755157
Metronomic Docetaxel and Bevacizumab in Patients With Small Cell Lung Cancertreatment2withdrawn
NCT06486428
Small Cell Lung Cancer Community Engagement to Eliminate Research DisparitiesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06457906
SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLCNo drug interventionstreatment3recruiting
NCT06424067
Phase 2 Study of Fingolimod in Lung Cancerstreatment2not_yet_recruiting
NCT05957510
Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From EGFR-mutated NSCLC After Treatmenttreatment2recruiting
NCT05829057
The IIT Study of Evaluation of P-IL-2 Single Agent and With Anti-PD-1No drug interventionstreatment1recruiting
NCT05800587
Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancertreatment2recruiting
NCT05761977
Durvalumab in Combination With Standard Chemotherapy of Patients With Extensive Stage Small Cell Lung CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT05354700
A Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy in Patients With Extensive Small Cell Lung Cancertreatment2unknown_status
NCT05068232
Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)treatment2recruiting
NCT04923776
Liver Directed RT + Chemo-immunotherapy for ES-SCLCtreatment2recruiting
NCT04790955
Effect of Combination Therapy on SCLC After Initial Treatment FailureNo drug interventionsNot AvailableNot Availableunknown_status
NCT04740021
Study of LP002 in Combination With Chemotherapy for Patients With Extensive Stage Small Cell Lung Cancertreatment2unknown_status
NCT04745689
Study of AZD2811 + Durvalumab in ES-SCLCtreatment2active_not_recruiting
NCT04596033
TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapytreatment1terminated
NCT04610684
Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastasestreatment2terminated
NCT04510129
A Multicenter Cancer Biospecimen Collection StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04187872
LITT and Pembrolizumab in Recurrent Brain Metastasistreatment1terminated
NCT04170946
Talazoparib and Thoracic RT for ES-SCLCNo drug interventionstreatment1recruiting
NCT04168281
Watchful Observation of Patients With LD-SCLC Instead of the PCINo drug interventionsotherNot Availableunknown_status
NCT04116320
Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid Tumorstreatment1active_not_recruiting
NCT04010357
Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLCtreatment2recruiting
NCT04683198
Camrelizumab Combined With Apatinib ,Carboplatin and Etoposide in Participants With ES-SCLCtreatment2unknown_status
NCT03583528
DOTATOC PET/CT for Imaging NET PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT03613753
Irinotecan Plus Lobaplatin Versus Irinotecan in the Second-line Treatment of Small Cell Lung Cancertreatment2unknown_status
NCT03514849
Clinical Study of Combined Radical Operation With Postoperative Adjuvant Chemotherapy and Prophylactic Cranial Irradiation in pT1-2N0M0 Stage of Small Cell Lung CancerNo drug interventionstreatmentNot Availablerecruiting
NCT04951115
A Trial With Chemotherapy, Immunotherapy, and Radiotherapy for Patients With Newly Diagnosed Stage IV Small Cell Lung Cancertreatment2completed
NCT04834778
A Study of HC-5404-FU to Establish the Maximum Tolerated Dose (MTD)No drug interventionstreatment1completed
NCT05578326
Study of Trilaciclib and Lurbinectidintreatment2recruiting
NCT05411679
EP0057 in Combination With Olaparib in Relapsed Advanced Gastric Cancer and Small Cell Lung Cancertreatment2withdrawn
NCT05091567
A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancertreatment3active_not_recruiting
NCT05223647
Chemo-immunotherapy Plus Thoracic Radiotherapy in Extensive Stage Small-cell Lung Cancertreatment3recruiting
NCT05253053
To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumorstreatment1 / 2recruiting
NCT04324437
eRAPID: Online Symptom Reporting in Lung CancerNo drug interventionsotherNot Availablecompleted
NCT03371979
Pegzilarginase and Pembrolizumab for Extensive Disease Small Cell Lung Cancertreatment1 / 2completed
NCT03239171
Bioinformation Therapy for Lung CancerNo drug interventionstreatment2 / 3completed
NCT02566993
Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin Versus CAV or Topotecan as Treatment in Patients With Small-Cell Lung Cancertreatment3completed
NCT00466466
Safety of RAD001 in Combination With Cisplatin and Etoposide in Lung Cancer Patientstreatment1completed
NCT04022876
A Study of ALRN-6924 for the Prevention of Chemotherapy-induced Side Effects (Chemoprotection)treatment1terminated
NCT04579757
Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumorstreatment1 / 2active_not_recruiting
NCT06295926
Serplulimab Combined With CCRT for LS-SCLC.treatment2recruiting
NCT04140526
Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCtreatment1 / 2recruiting
NCT01429766
A Prospective Study of Variation in Breath Holding Times at Various Phases of Respiration During the Course of Radiotherapy Including the Effect of Respiratory Training in Lung Cancer PatientsNo drug interventionssupportive_care2unknown_status
NCT01064466
Pharmacogenomics IND EXEMPT SNP Clinical Study - Etoposide and Single Nucleotide Polymorphismshealth_services_research2 / 3active_not_recruiting
NCT00812266
Topotecan and Cisplatin Versus Etoposide and Carboplatin in 1st Line Treatment of Patients With Small Cell Lung Cancer and Extensive Disease (SCLC-ED)treatment3terminated
NCT01500720
Cabazitaxel Compared to Topotecan for the Treatment of Small Cell Lung Cancertreatment2completed
NCT04192682
Anlotinib Combined With Sintilimab as Second-line Treatment or Beyond in Patients With Small Cell Lung Cancertreatment2 / 3unknown_status
NCT03009682
Olaparib Monotherapy in Relapsed Small Cell Lung Cancer Patients With HR Pathway Gene Mutations Not Limited to BRCA 1/2 Mutations, ATM Deficiency or MRE11A Mutationstreatment2completed
NCT00765973
Topotecan Liposomes Injection for Small Cell Lung Cancer (SCLC), Ovarian Cancer and Other Advanced Solid Tumorstreatment1completed
NCT01497873
A Randomized Study to Compare the Efficacy and Safety of Belotecan and Topotecan as Monotherapy for Sensitive-Relapsed Small Cell Lung Cancertreatment2completed
NCT02577627
Multi-Indication, Retrospective Oncological Study to Validate the Accuracy in Predicting TTP by PrediCare in Patients Under SOCNo drug interventionsNot AvailableNot Availableunknown_status
NCT00043927
Extensive Small Cell Lung Cancer Treatment Using An Investigational Drug Plus Chemotherapy In Chemotherapy-Naive Adultstreatment3completed
NCT00697476
Study of Oral Vorinostat in Combination With Topotecan in Patients With Chemosensitive Recurrent SCLCtreatment1 / 2terminated
NCT05572476
Lurbinectedin Combined With Durvalumab in Pre-treated Patients With Extensive Stage Small-cell Lung Cancertreatment2withdrawn
NCT06406660
Patient-derived Organoid Drug Sensitivity Guided Treatment for Recurrent Small Cell Lung CancerNo drug interventionstreatmentNot Availablerecruiting
NCT04451460
Effect of Hyponatremia in Small Cell Lung CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT00388960
Study of Amrubicin With or Without Cisplatin Versus Etoposide-cisplatin for Extensive Stage Small Cell Lung Cancertreatment2completed
NCT03467360
Inhibition of CArbonic Anhydrase in Combination With Platinum and Etoposide-based Radiochemotherapy in Patients With Localized Small Cell Lung Cancertreatment1recruiting
NCT00930891
Bevacizumab in Extensive Small Cell Lung Cancertreatment2 / 3completed
NCT03365791
PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignanciestreatment2completed
NCT03898791
A Study of LY3295668 Erbumine in Participants With Extensive-stage Small-Cell Lung Cancertreatment1completed
NCT00465491
Study of Picoplatin Efficacy After Relapsetreatment3unknown_status
NCT03219762
Study of Nab-paclitaxel in Sensitive and Refractory Relapsed SCLChealth_services_research2unknown_status
NCT00702962
Carboplatin and Etoposide in Combination With Vorinostat for Patients With Extensive Stage Small Cell Lung Cancertreatment1 / 2terminated
NCT00043862
The Study Of An Oral Drug Called A Radiation Sensitizer In Patients With Newly Diagnosed Small Cell Lung Cancer (SCLC)treatment2completed
NCT02391480
A Study Evaluating the Safety and Pharmacokinetics of ABBV-075 in Subjects With Cancertreatment1completed
NCT02735980
A Study of Prexasertib (LY2606368) in Participants With Extensive Stage Disease Small Cell Lung Cancertreatment2completed
NCT06581380
JK-1201I Compared with Topotecan in Patients with Relapsed Extensive Stage Small Cell Lung Cancertreatment3not_yet_recruiting
NCT00065429
Safety Study Using Weekly Infusions of BB-10901 in Patients With Small Cell Lung Cancertreatment1 / 2completed
NCT02995889
FLT-PET for Early Detection of Relapse in Patients With Irradiated Lung CancerNo drug interventionsdiagnosticNot Availablecompleted
NCT00349492
A Study Comparing Etoposide/Cisplatin With Irinotecan/Cisplatin to Treat Extensive Disease Small Lung Cancertreatment3completed
NCT00695292
Irinotecan, Carboplatin, and Sunitinib in First Line Extensive-Stage Small Cell Lung Cancertreatment2completed
NCT02815592
Trial of BMS-986012 in Combination With Platinum and Etoposidetreatment1completed
NCT00912392
Etoposide-Carboplatin Alone or With Endostar for Extensive Disease Small Cell Lung Cancer (ED-SCLC)treatment2completed
NCT00374140
Phase II Trial of RAD001 (Everolimus) in Previously Treated Small Cell Lung Cancertreatment2completed
NCT03228667
QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitorstreatment2active_not_recruiting
NCT00132704
An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing RadiationNo drug interventionsNot AvailableNot Availablecompleted
NCT05769504
Examining Clinical Trial Participation for Small Cell Lung Cancer PatientsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02250404
Molecular Signatures of Relapse in Tissue Samples From Patients With Small Cell Lung Cancer Who Are Receiving Cisplatin and EtoposideNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03076372
A Study Evaluating MM-310 in Patients With Solid TumorsNo drug interventionstreatment1unknown_status
NCT02425072
NovoTTF-100A Therapy for Refractory CNS Involved Small Cell Lung CancerNo drug interventionstreatment2withdrawn
NCT02105168
Identification of Marker of Primary or Acquired Resistance to Anti Tumorous TreatmentNo drug interventionsscreeningNot Availableunknown_status
NCT00916669
A Randomized Study to Evaluate the Effect of Two Different Doses of Enoxaparin Sodium in Combination With Standard Chemotherapy in Patients With Stage Small Cell Lung Cancer (SCLC)treatment2withdrawn
NCT04504669
First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumourstreatment1active_not_recruiting
NCT00319969
Study Comparing Amrubicin Versus Topotecan in Patients With Small Cell Lung Cancer Who Have Responded to Prior Therapy.treatment2completed
NCT05889546
Rapid Autopsy Protocol for Patients With Small Cell Lung CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT02738346
SCLC on the 2nd Line With Relapsed After Response to Chemotherapy GFPC 01-2013treatment3unknown_status
NCT06364046
Efficacy and Safety of DEB-BACE Combined With Serplulimab in First-line Treatment of SCLCtreatmentNot Availablenot_yet_recruiting
NCT01040312
An Observational Study of CPT-11 Plus Platinum Analogues Regimens and UGT1A1 Genotypes in Solid TumorsNot AvailableNot Availablecompleted
NCT03061812
Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)treatment3completed
NCT04870112
A Study to Evaluate Subcutaneous Durvalumab in Patients With Non-Small Cell Lung Cancer and Small Cell Lung Cancertreatment1terminated
NCT02349412
Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family CaregiversNo drug interventionssupportive_care3completed
NCT02337712
Once-daily Simultaneous Modulated Accelerated Thoracic Radiotherapy in Limited Small-cell Lung Cancertreatment2unknown_status
NCT04920981
Atezolizumab Combined With Chemotherapy in Extensive Stage SCLCNo drug interventionsNot AvailableNot Availablecompleted
NCT02200081
Randomized Study of Maintenance Therapy With MGN1703 in Patients With SCLCNo drug interventionstreatment2completed
NCT04079595
Closed vs. Open Face Masks for Cranial RadiotherapyNo drug interventionsotherNot Availablecompleted
NCT02949895
Study of BMS-986012 in Subjects With Small Cell Lung Canertreatment1completed
NCT04890795
A Phase Ib / IIA Study of AL8326 in Small Cell Lung CancerNo drug interventionstreatment1 / 2unknown_status
NCT04209595
PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancerstreatment1 / 2active_not_recruiting
NCT03890055
Clinical Study of First-line Treatment of Small Cell Lung Cancer (SCLC) With Anlotinib Hydrochloridetreatment4unknown_status
NCT03913455
Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung Cancertreatment2completed
NCT04073550
Study of Anlotinib Hydrochloride Capsule in Subjects With Small Cell Lung Cancertreatment3unknown_status
NCT02738723
SBRT Compared With IMRT Concurrently With Chemotherapy in Treating Patients With LS-SCLCNo drug interventionstreatment2unknown_status
NCT00717938
A Study of Standard Treatment +/- Enoxaparin in Small Cell Lung Cancertreatment3completed
NCT00418743
Second-line Treatment in Patients With Small Cell Lung Cancer (SCLC)No drug interventionsNot AvailableNot Availableunknown_status
NCT02913443
A Dose Finding and Expansion Study of RO7051790 Administered Orally in Participants With Relapsed, Extensive-Stage Disease Small Cell Lung Cancer (ED SCLC)No drug interventionstreatment1completed
NCT05296603
Efficacy and Biomarker Explanation of IBI-322 Plus Lenvatinib on Extensive Stage Small Cell Lung Cancertreatment2recruiting
NCT03503890
Expanded Access to Rovalpituzumab TesirineNot AvailableNot Availableno_longer_available
NCT02289690
Dose Escalation and Double-blind Study of Veliparib in Combination With Carboplatin and Etoposide in Treatment-naive Extensive Stage Disease Small Cell Lung Cancertreatment1 / 2completed
NCT03392064
A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLCtreatment1suspended
NCT06257264
A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumorstreatment1recruiting
NCT00447421
A Study to Treat Small Cell Lung Cancer With a Combination of Cisplatin, Pemetrexed, and Radiotherapytreatment1 / 2terminated
NCT04256421
A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancertreatment3active_not_recruiting
NCT02995902
FLT-PET/DW-MRI for Detection of Brain Metastases and Early Therapy Evaluation in Patients With Small Cell Lung CancerNo drug interventionsdiagnosticNot Availablecompleted
NCT00531284
Phase 1b/2 Study of Carfilzomib in Relapsed Solid Tumors, Multiple Myeloma, or Lymphomatreatment1 / 2completed
NCT01025284
A Study for Participants With Small-Cell Lung Cancertreatment2completed
NCT02906384
Memory and MRI Changes With Hippocampus Avoidance Prophylactic Cranial Irradiation(HA-PCI) for Small Cell Lung Cancer(SCLC)No drug interventionstreatment2unknown_status
NCT06498479
ARTEMIS-008:HS-20093 Compared With Topotecan in Subjects With Relapsed Small Cell Lung Cancertreatment3not_yet_recruiting
NCT01840579
Study of Pembrolizumab (MK-3475) Monotherapy in Advanced Solid Tumors and Pembrolizumab Combination Therapy in Advanced Non-small Cell Lung Cancer/ Extensive-disease Small Cell Lung Cancer (MK-3475-011/KEYNOTE-011)treatment1completed
NCT06047379
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasistreatment1 / 2recruiting
NCT03334487
Study Evaluating the Safety of Rovalpituzumab Tesirine for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Small Cell Lung Cancertreatment3withdrawn
NCT04553133
PF-07104091 as a Single Agent and in Combination Therapytreatment1 / 2active_not_recruiting
NCT02046733
Small Cell Lung Carcinoma Trial With Nivolumab and IpiliMUmab in LImited Diseasetreatment2unknown_status
NCT02331251
Study of Pembrolizumab Plus Chemotherapy in Patients With Advanced Cancer (PembroPlus)treatment1 / 2terminated
NCT00547651
AMR PH GL 2007 CL001 Phase 3 Trial in Patients With Small Cell Lung Cancer After Failure of First-Line Chemotherapytreatment3completed
NCT01069653
Safety Study of Peptide Cancer Vaccine To Treat HLA-A*24-positive Advanced Small Cell Lung CancerNo drug interventionstreatment1completed
NCT00290953
Evaluation of the Overall Survival of Meclinertant Versus Placebo After a First Line Chemotherapy With Cisplatin + Etoposidetreatment2 / 3completed
NCT03958045
Combination Rucaparib With Nivolumab in Small Cell Lung Carcinomatreatment2active_not_recruiting
NCT04885998
AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)treatment1active_not_recruiting
NCT03752398
A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)treatment1completed
NCT00213798
Detection of Plasma DNA in Non Small Cell and Small Cell Lung Cancer PatientsNo drug interventionsscreeningNot Availablecompleted
NCT03585998
Chemoradiation With Durvalumab Followed by Durvalumab Maintenance for Limited Disease Small Cell Lung Cancertreatment2unknown_status
NCT03162705
Molecular Profiling in Small Cell Lung CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT03703297
Study of Durvalumab + Tremelimumab, Durvalumab, and Placebo in Limited Stage Small-Cell Lung Cancer in Patients Who Have Not Progressed Following Concurrent Chemoradiation Therapytreatment3active_not_recruiting
NCT03059797
Study of Anlotinib in Patients With Small Cell Lung Cancer (ALTER1202)treatment2completed
NCT04314297
Anlotinib In Combination With Durvalumab As Sequential Therapy of Thoracic Radiotherapy After Induction Chemotherapy For Extensive-Stage Small Cell Lung Cancer:A Single Arm Studytreatment2unknown_status
NCT02262897
The Efficacy and Safety of Nab-paclitaxel in Pretreated Patients With Extensive Disease of Small Cell Lung Cancertreatment2unknown_status
NCT04041011
A Study of SHR-1316 and Fluzoparib(SHR-3162) in Small Cell Lung Cancer Patientstreatment1completed
NCT03080311
A Study of APG-1252 in Patients With SCLC or Other Solid Tumorstreatment1completed
NCT00397293
Study of AT-101 in Combination With Topotecan in Relapsed/Refractory Small Cell Lung Cancertreatment1 / 2completed
NCT05797493
Panomic Approach to Immune-Connected Assays in Small Cell Lung CancerNot AvailableNot Availablerecruiting
NCT00375193
Study of Amrubicin in Patients With Small Cell Lung Cancer Refractory or Progressive to Prior Therapytreatment2completed
NCT03116971
Phase Ib/II Study of M3814 With Etoposide and Cisplatin in Small Cell Lung Cancer (SCLC) Extensive Disease (ED)treatment1terminated
NCT03093688
Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid TumorNo drug interventionstreatment1 / 2unknown_status
NCT00298688
A Study of IRESSA in Relapsed and Refractory Small Cell Lung Cancertreatment2completed
NCT04400188
A Study of Fluzoparib (SHR-3162) and Temozolomide With or Without SHR-1316 in Treating Patients With Replapsed Small Cell Lung Cancertreatment1 / 2active_not_recruiting
NCT02688907
Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients With MYC Family Amplification or CDKN2A Mutation Combined With TP53 Mutationtreatment2terminated
NCT01401907
Early Palliative Care in Advanced Lung and Gastrointestinal MalignanciesNo drug interventionssupportive_careNot Availablecompleted
NCT03782207
A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical PracticeNot AvailableNot Availableactive_not_recruiting
NCT00483509
Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Metastatic Small Cell Lung Carcinomatreatment2completed
NCT02980809
Topotecan Plus Apatinib Versus Topotecan Alone as Second-line Therapy in Small-cell Lung Cancertreatment2unknown_status
NCT04731909
Toripalimab Combined With Anlotinib, Etoposide and Platinum in the Treatment of Extensive-stage Small Cell Lung CancertreatmentNot Availableunknown_status
NCT03670056
Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapytreatment2active_not_recruiting
NCT01809756
The Effect of Caphosol® on the Development of Esophagitis in (N)SCLC Patients Treated With Concurrent Chemo/RadiotherapyNo drug interventionspreventionNot Availableterminated
NCT00686985
Docetaxel - Carboplatin as Second Line Treatment in Patients With Small Cell Lung Cancertreatment2unknown_status
NCT00080015
Diflomotecan (BN80915) Administered Once Every 3 Weeks in Treating Patients With Sensitive Small Cell Lung Cancer (SCLC)treatment2completed
NCT00363415
Study of Pemetrexed and Carboplatin Compared With Etoposide Carboplatin to Treat Extensive-Stage Small Cell Lung Cancertreatment3completed
NCT04291937
A Multicenter Expanded Access Treatment Protocol of Lurbinectedin in Previously Treated SCLC in the USANot AvailableNot Availableapproved_for_marketing
NCT04210037
Study of APG-1252 Plus Paclitaxel in Patients With Relapsed/Refractory Small Cell Lung Cancertreatment1 / 2terminated
NCT00455052
A Study of Intravenous XMT-1001 in Patients With Advanced Solid Tumorstreatment1completed
NCT02367352
Alisertib (MLN8237) in Combination With Weekly Paclitaxel in East Asian Patients With Advanced Solid Tumorstreatment1terminated
NCT02945852
Apatinib for Extensive Stage Small Cell Lung Cancer After Second/Third Line Chemotherapy.treatment2completed
NCT01392352
HYPAZ: Hypertension Induced by Pazopanibbasic_science2terminated
NCT04128800
Appatinib Combined With S-1 in the Treatment of Small Cell Lung Cancertreatment2unknown_status
NCT00317200
A Study of Paclitaxel Plus Bevacizumab in Patients With Chemosensitive Relapsed Small Cell Lung Cancertreatment2completed
NCT03983759
Study of Sintlimab Maintenance Therapy in Patients With Extensive Small Cell Lung Cancertreatment2unknown_status
NCT01221675
TF2- Small Cell Lung Cancer Radio ImmunotherapyNo drug interventionstreatment1 / 2completed
NCT01780675
Hippocampus Avoidance PCI vs PCINo drug interventionstreatment3completed
NCT03366675
AZD 2811 Monotherapy in Relapsed Small Cell Lung Cancer Patients [SUKSES-N3]No drug interventionstreatment2terminated
NCT05886075
A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Advanced Solid TumorsNo drug interventionstreatment0recruiting
NCT02499770
Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Etoposide and Carboplatin in Extensive Stage Small Cell Lung Cancer (SCLC)treatment1 / 2completed
NCT05371899
Mass Balance Study of [14C]ChiauranibtreatmentNot Availablecompleted
NCT01487499
Bronchoscopic Intratumoral Chemotherapy for Small Cell Lung Cancer (SCLC)treatment3terminated
NCT01881906
Exercise in Advanced Stage Lung Cancer PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT01417806
Trial of pasireotideLAR and Topotecan in Relapsed or Refractory Small Cell Lung Cancertreatment2unknown_status
NCT04472949
Thoracic Radiotherapy Plus Maintenance Durvalumab After First Line Carboplatin and Etoposide Plus Durvalumab in Extensive-stage Disease Small Cell Lung Cancer (ED-SCLC).treatment2active_not_recruiting
NCT05191849
Circulating EV Long RNA Profiles in SCLCNo drug interventionsdiagnosticNot Availablerecruiting
NCT03088813
Study of Irinotecan Liposome Injection (ONIVYDE®) in Patients With Small Cell Lung Cancertreatment3completed
NCT04830813
Phase 3 Clinical Study of Chiauranib Capsule in Patients With Small-cell Lung Cancertreatment3recruiting
NCT00951613
A Study of NK012 in Patients With Relapsed Small Cell Lung Cancertreatment2completed
NCT06514118
Chemoimmunotherapy Plus Residual Lesion Irradiation for the Treatment of Extensive Stage Small-cell Lung CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT06103682
LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)No drug interventionstreatmentNot Availablerecruiting
NCT06022757
Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)treatment1 / 2recruiting
NCT05636618
Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine TumorsNo drug interventionstreatment1 / 2recruiting
NCT04706962
TH1902 in Patients With Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT04542369
Pilot Study of PD-1inhibitor (Tislelizumab) Plus Chemotherapy as Neoadjuvant Therapy for Limited-Stage Small-Cell Lung Cancertreatment2recruiting
NCT04471727
A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)treatment1 / 2recruiting
NCT04234113
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumorstreatment1active_not_recruiting
NCT04247126
A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumorstreatment1completed
NCT04106167
Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular ImmunotherapyNo drug interventionsNot AvailableNot Availableterminated
NCT03896958
The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)No drug interventionsNot AvailableNot Availableunknown_status
NCT03761914
Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancerstreatment1 / 2active_not_recruiting
NCT04691063
The Study is Being Conducted to Evaluate the Efficacy and Safety of SHR-1316 in Combination With Chemo-radiotherapy in Patients With LS-SCLC.treatment3enrolling_by_invitation
NCT03583086
Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumorstreatment1 / 2active_not_recruiting
NCT03540420
Atezolizumab After Concurrent Chemo-radiotherapy Versus Chemo-radiotherapy Alone in Limited Disease Small-cell Lung Cancertreatment2active_not_recruiting
NCT03547804
A Prospective, Single-center, One-arm Clinical Study of Apatinib Combined With Chemotherapy for Pretreated Patients With Advanced Small Cell Lung Cancertreatment2completed
NCT03523234
Neoadjuvant Therapy Combined With Radical Surgery for the Treatment of Small Cell Lung Cancer (SCLC) in II and IIIA StageNo drug interventionstreatmentNot Availableunknown_status
NCT04342429
Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung CancerNo drug interventionstreatmentNot Availablerecruiting
NCT04640480
Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in Patients With Tumorstreatment1not_yet_recruiting
NCT04696939
Combined Atezolizumab and Chemotherapy (Carboplatin Plus Etoposide) in Neoadjuvant Treating Limited-Stage Small Cell Lung Cancer Patientstreatment2unknown_status
NCT05254119
DIAGNOSIS, TREATMENT AND OUTCOME OF LUNG CANCER PATIENTSNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03417895
SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapytreatment2completed
NCT03219268
A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasmstreatment1completed
NCT02622581
Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02688673
DC Vaccine Combined With CIK Cells in Patients With SCLCNo drug interventionstreatment1 / 2unknown_status
NCT00286169
Amrubicin Study for Elderly Patients With Extensive-disease Small-cell Lung Cancer (ED-SCLC)treatment3terminated
NCT00144989
A Study Comparing Irinotecan and Cisplatin (IP) With Etoposide and Cisplatin (EP) Following EP/TRT for LD-SCLCtreatment3completed
NCT04272034
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT02039518
Study of Gemcitabine Maintenance Treatment in Patients With Extensive SCLC Patientstreatment2unknown_status
NCT05731518
SC0245 and Irinotecan in Treating Patients With Relapsed Extensive-Stage Small Cell Lung Cancer (ES-SCLC)treatment1 / 2recruiting
NCT05924841
A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Extensive Stage Small Cell Lung CancerNo drug interventionstreatment2recruiting
NCT01426841
Pilot Project of Adaptive Thoracic Radiotherapy for Small Cell Lung CancerNo drug interventionstreatment1unknown_status
NCT04698941
Combined Simvastatin and Albumin Paclitaxel in Treating ES-SCLC Patients Relapsed From 1st Chemotherapytreatment2unknown_status
NCT01752517
Vinorelbine and Ifosfamide as Third-line Treatment for Refractory Small Cell Lung CancerNot AvailableNot Availableunknown_status
NCT00452634
Irinotecan/Cisplatin Plus Simvastatin in Extensive Disease-Small Cell Lung Cancer (ED-SCLC)treatment2completed
NCT00454324
Study of Abraxane and Carboplatin to Treat Small Cell Lung Cancertreatment2terminated
NCT03297424
A Study of PLX2853 in Advanced Malignancies.No drug interventionstreatment1completed
NCT02109016
A Study to Assess the Efficacy and Safety of the VEGFR-FGFR Inhibitor, Lucitanib, Given to Patients With Advanced/Metastatic Lung Cancer and FGF, VEGF, or PDGF Related Genetic Alterationstreatment2terminated
NCT00216216
Pemetrexed in Patients With Chemosensitive and Chemoresistant Relapsed Small Cell Lung Cancertreatment2terminated
NCT04005716
Study of Platinum Plus Etoposide With or Without BGB-A317 in Participants With Untreated Extensive-Stage Small Cell Lung Cancertreatment3completed
NCT01421316
Hair-sparing Whole Brain RadiotherapyNo drug interventionstreatment2terminated
NCT03325816
Nivolumab and 177Lu-DOTA0-Tyr3-Octreotate for Patients With Extensive-Stage Small Cell Lung Cancertreatment1 / 2completed
NCT00298896
Safety and Efficacy Clinical Study of SNS-595 in Patients With Advanced Small Cell Lung Cancertreatment2completed
NCT00168896
A Study for Small Cell Lung Cancer (SCLC) in Extensive Disease Stagetreatment2 / 3unknown_status
NCT00526396
STAD-1 Small Cell Lung Cancer Toxicity Adjusted Dosing Studytreatment3active_not_recruiting
NCT01165658
Study of Hypofractionated Proton Radiation Therapy in Thoracic MalignanciesNo drug interventionstreatment1terminated
NCT00527735
Phase II Study for Previously Untreated Subjects With Non Small Cell Lung Cancer (NSCLC) or Small Cell Lung Cancer (SCLC)treatment2completed
NCT05337735
A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancerstreatment2suspended
NCT03419286
Transformation Into Small Cell Lung Cancer : a Mode of Resistance to TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00156286
Gleevec Maintenance Therapy After Induction Irinotecan and Cisplatin in Patients With C-Kit Positive Extensive SCLCtreatment2completed
NCT06467786
Study on the Therapeutic Effect of Irinotecan Liposomes in Small Cell Lung Cancertreatment4recruiting
NCT00921739
Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic MalignanciesNo drug interventionstreatment1completed
NCT03086239
A Study on the Safety and Tolerability of Rovalpituzumab Tesirine in Japanese Patients With Advanced, Recurrent Small Cell Lung Cancertreatment1completed
NCT01592422
Maintenance Therapy With Autologous Cytokine-induced Killer Cells for Small Cell Lung CancerNo drug interventionstreatment2unknown_status
NCT04361825
Durvalumab(MEDI4736) and AZD6738 Combination Therapy in Relapsed Small Cell Lung Cancer Subjectstreatment2completed
NCT02171325
Study of Different Doses of Irinotecan and Cisplatin for First-line Extensive-stage Small-cell Lung Cancer Treatmenttreatment2unknown_status
NCT00546130
Feasibility Study of CDDP + CPT-11 + PSK for Extensive-Stage Disease (ED) Small Cell Lung Cancertreatment2unknown_status
NCT03098030
Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung Cancertreatment2 / 3completed
NCT00856830
Bendamustine With Irinotecan Followed by Etoposide/Carboplatin for Patients With Extensive Stage Small Cell Lung Cancertreatment1 / 2completed
NCT06500026
A Study Comparing BL-B01D1 With Topotecan in Patients With Recurrent Small Cell Lung Cancertreatment3recruiting
NCT00494026
Chemotherapy and Radiotherapy to Treat Patients With Limited Stage of Small Cell Lung Cancer (SCLC)treatment2terminated
NCT00613626
Cisplatin + Etoposide +/- Concurrent ZD6474 in Previously Untreated Extensive Stage Small Cell Lung Cancertreatment2completed
NCT03026166
A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancertreatment1 / 2terminated
NCT05429866
Immunological Variables Associated to ICI Toxicity in Cancer Patientsother2recruiting
NCT04434482
IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancertreatment1 / 2recruiting
NCT01575782
Chloroquine as an Anti-autophagic Radiosensitizing Drug in Stage I-III Small Cell Lung Cancertreatment1terminated
NCT02649673
LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignanciestreatment1terminated
NCT01159327
Study of Sorafenib Maintenance in Patients With ED-SCLC After Response to Induction Chemotherapytreatment2terminated
NCT04802876
Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumorstreatment2recruiting
NCT05628376
TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVONo drug interventionsNot AvailableNot Availablerecruiting
NCT03639194
A Study of ABBV-011 Alone and in Combination With Budigalimab (ABBV-181) in Participants With Relapsed or Refractory Small Cell Lung Cancertreatment1completed
NCT05245994
An Open Label, Multicenter Phase 2 Study of Durvalumab (MEDI4736) + Olaparib as Maintenance Therapy in Chinesetreatment2unknown_status
NCT03391362
Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain MetastasesNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05363280
Phase 2 Safety and Efficacy Evaluation of AL8326 in ≥2nd Line SCLCNo drug interventionstreatment2recruiting
NCT04952480
Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung CancerNo drug interventionstreatment2recruiting
NCT03741829
TS Overexpression in SCLC: Mechanism and Therapeutic TargetingNo drug interventionsNot AvailableNot Availablecompleted
NCT04501029
A Study of Gimatecan (ST1481) in Small Cell Lung Cancertreatment2unknown_status
NCT00252889
Doxil Topotecan Doublet Cancer Studytreatment1completed
NCT05595889
Surufatinib Combined With Irinotecan as a Second-line Treatment for Small Cell Lung Cancertreatment2not_yet_recruiting
NCT04782089
Study of PD-1 Antibody and PARP Inhibitor in Extensive Stage Small Cell Lung CancertreatmentNot Availableunknown_status
NCT01831089
Phase I Study of Lurbinectedin (PM01183) in Combination With Paclitaxel, With or Without Bevacizumab, in Selected Advanced Solid Tumorstreatment1completed
NCT05271292
Chiauranib for Advanced Solid Malignant Tumors and Relapsed/Refractory SCLC.treatment1 / 2recruiting
NCT05619744
A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of RO7616789 in Advanced Small Cell Lung Cancer and Other Neuroendocrine Carcinomastreatment1recruiting
NCT03059667
Immunotherapy as Second-line in Patient With Small Cell Lung Cancertreatment2completed
NCT04924101
Efficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99)treatment2active_not_recruiting
NCT04985201
Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapytreatment2unknown_status
NCT03776604
PEG-rhG-CSF in Elderly Patients With Small Cell Lung Cancer Receiving ChemotherapyNo drug interventionspreventionNot Availableunknown_status
NCT04624204
Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)treatment3active_not_recruiting
NCT04032704
A Study of Ladiratuzumab Vedotin in Advanced Solid Tumorstreatment2terminated
NCT02446704
Study of Olaparib and Temozolomide in Patients With Recurrent Small Cell Lung Cancer Following Failure of Prior Chemotherapytreatment1 / 2unknown_status
NCT02978404
Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastasestreatment2completed
NCT05563272
89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumorsdiagnostic2recruiting
NCT03488472
Radiosurgery Plus NovoTTF-200A for Metastatic Small Cell Lung Cancer to the BrainNo drug interventionstreatmentNot Availableterminated
NCT01242072
Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With MalignanciesNo drug interventionstreatment1unknown_status
NCT03997968
A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumorstreatment1 / 2active_not_recruiting
NCT02674568
Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung Cancertreatment2completed
NCT03410368
NK Cell-based Immunotherapy as Maintenance Therapy for Small-Cell Lung Cancer.treatment2unknown_status
NCT02722369
STUDY 15 - Comparing Gemcitabine/Carboplatin and Hydroxychloroquine Versus Carboplatin/Etoposide Therapy Alone in Small Cell Lung Cancer (SCLC)treatment2terminated
NCT01253369
Pazopanib in Patients With Relapsed or Refractory Small Cell Lung Cancertreatment2completed
NCT01591512
A Prospective Longitudinal Collection of Subjects Diagnosed With Small Cell Lung CancerNo drug interventionsNot AvailableNot Availableterminated
NCT00116610
Picoplatin as Second-Line Therapy for Patients With Small Cell Lung Cancertreatment2completed
NCT04422210
A Study Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Venetoclax In Combination With Atezolizumab, Carboplatin, And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).treatment1terminated
NCT03841110
FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumorstreatment1completed
NCT04381910
Irinotecan Hydrochloride Liposome Injection (LY01610) For Small Cell Lung Cancertreatment2completed
NCT04590781
Safety and Efficacy of XmAb18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancertreatment1 / 2terminated
NCT01079481
Combination Anticancer Therapy of Paclitaxel and Everolimus for Relapsed or Refractory Small Cell Lung Cancertreatment1completed
NCT00883181
A Study of Neutropenia and Anemia Management in Patients With Solid Tumors Receiving Myelotoxic ChemotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT01125995
Early Versus Late Concurrent Chemoradiation for Limited Stage Small-cell Lung CancerNo drug interventionstreatment3completed
NCT00776295
Autologous SCT Followed by Dendritic Cell p53 Vaccination in Patients With Limited Stage Small Cell Lung CancerNo drug interventionstreatment2terminated
NCT02500914
SC-002 in Small Cell Lung Cancer and Large Cell Neuroendocrine CarcinomaNo drug interventionstreatment1terminated
NCT01182155
Breath Analysis for Evaluation of Radiation Exposure in Lung Cancer Patients Treated With RadiationNo drug interventionsNot AvailableNot Availablecompleted
NCT03106155
Vistusertib (AZD2014) Monotherapy in Relapsed Small Cell Lung Cancer Patients Harboring RICTOR Amplificationtreatment2terminated
NCT02348450
Irinotecan Plus Cisplatin Compared With Etoposide Plus Cisplatin for Extensive Stage Small-cell Lung Cancertreatment4unknown_status
NCT00572923
Concurrent Chemo-Radiotherapy for Limited Disease Small Cell Lung Cancer (LD-SCLC) on Basis of FDG-PET-ScansNo drug interventionsNot AvailableNot Availablecompleted
NCT01173523
Study of Hsp90 Inhibitor, STA-9090 for Relapsed or Refractory Small Cell Lung Cancertreatment2completed
NCT04841538
A Study of ES101 (PD-L1x4-1BB Bispecific Antibody) in Patients With Advanced Malignant Thoracic TumorsNo drug interventionstreatment1 / 2withdrawn
NCT03216343
Phase Ib/II Study of Chiauranib in Patients With Small Cell Lung Cancertreatment1completed
NCT06228326
A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the LungsNo drug interventionstreatment1recruiting
NCT00997061
SCOT Registry: Small Cell Lung Cancer Treatment and OutcomeNot AvailableNot Availablecompleted
NCT00046111
A Bioequivalence Study of Two Oral Formulations of Topotecan in Patients With Advanced Solid Tumorstreatment1completed
NCT03499678
Lung Cancer Screening Using DNA Methylation Changes in Circulated Tumor and PBMC DNANo drug interventionsNot AvailableNot Availableterminated
NCT04440800
Feasibility of Wearable Activity Trackers for Detection of TOXicity in People Receiving Systemic Anticancer TreatmentNo drug interventionsNot AvailableNot Availableunknown_status
NCT00698516
Study of Oral Topotecan With Bevacizumab for Recurrent Small Cell Lung Cancertreatment2completed
NCT01313663
A Study to Evaluate Pazopanib in Comparison to Pemetrexed in Maintenance Setting in Non-progressing Subjects With Metastatic Stage IVA and IVB Non-squamous Non-small Cell Lung Cancer (NSCLC) Populationtreatment2terminated
NCT00316186
First-line Treatment Of Subjects With Extensive Disease Small Cell Lung Cancer With Weekly Hycamtin And Paraplatintreatment2completed
NCT00276276
Active Symptom Control Alone Or In Combination With Oral Topotecan In Patients With Relapsed Resistant Small Cell Lung Cancertreatment3completed
NCT04660929
CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumorstreatment1active_not_recruiting
NCT01037023
Regulatory Hycamtin(Oral) PMSNot AvailableNot Availablecompleted
NCT06293833
Implementation of Lung Cancer Screening in the First Line Zone of ZORA (Flanders), Using a Low Dose CT-scanNo drug interventionsscreeningNot Availableenrolling_by_invitation
NCT00320359
Topotecan Plus Cisplatin Versus Etoposide Plus Cisplatin In 1st Line Extensive Disease Small Cell Lung Cancertreatment3completed
NCT04986670
NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung CancerNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT05228496
A Study to Investigate the Efficacy and Safety of Tislelizumab Combined With Sitravatinib as Maintenance Therapy for ES-SCLCtreatment2active_not_recruiting
NCT05320458
Pulmonary Rehabılıtatıon Wıth Non-Small Lung CancerNo drug interventionstreatmentNot Availableunknown_status
NCT00259935
A Study To Determine If Two Different Versions Of Topotecan Have The Same Potency In Patients With Advanced Solid Tumorstreatment1completed
NCT04314895
Trial of NanoPac Intratumoral Injection in Lung Cancertreatment2completed
NCT01071434
Feasibility of Using Real-time Cine-MRI for Treating Moving & Deforming TumorsNo drug interventionsNot AvailableNot Availableterminated
NCT01188486
Pulmonary Interstitial Lymphography in Early Stage Lung Cancerdevice_feasibilityNot Availableterminated
NCT01137162
Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR InhibitorsNo drug interventionsNot AvailableNot Availableterminated
NCT02030184
Phase I/II Trial of Rhenium 188-P2045 in Small Cell Lung Cancer and Other Advanced Neuroendocrine Carcinomastreatment1 / 2withdrawn
NCT04727853
Study of Irinotecan Liposome Injection as Second-line Regimen in Patients With Small Cell Lung Cancer (SCLC)treatment2completed
NCT01719861
Phase 2a Desipramine in Small Cell Lung Cancer and Other High-Grade Neuroendocrine Tumorstreatment2terminated
NCT03538028
A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignanciestreatment1completed
NCT03066778
A Study of Pembrolizumab (MK-3475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for Participants With Extensive Stage Small Cell Lung Cancer (MK-3475-604/KEYNOTE-604)treatment3completed
NCT05652686
A Study of PT217 in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)treatment1 / 2recruiting
NCT01210131
Hypoxia-guided Radiotherapy With Cisplatin-etoposide in Stage I-III : Small Cell Lung Cancer(SCLC)No drug interventionstreatmentNot Availablewithdrawn
NCT05158491
Safety, Tolerability and Preliminary Efficacy of JK1201I in Patients With SCLCtreatment1 / 2unknown_status
NCT06485544
Neoadjuvant Adebrelimab in Resectable SCLC: A Randomized Trialtreatment2recruiting
NCT02934503
Study of Pembrolizumab and Chemotherapy With or Without Radiation in Small Cell Lung Cancer (SCLC)treatment2terminated
NCT01904253
A Phase 2 Study Comparing TAS-102 Versus Topotecan or Amrubicin to Treat Small Cell Lung Cancer Following Platinum-Based Chemotherapytreatment2terminated
NCT03460977
Mevrometostat Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphomatreatment1recruiting
NCT03708328
A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumorstreatment1completed
NCT02769832
Nab-Paclitaxel With Gemcitabine for Relapsed Small Cell Cancertreatment2active_not_recruiting
NCT03811652
A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid TumorsNo drug interventionstreatment1completed
NCT05027100
Tislelizumab Combined With Anlotinib and 2-cycles Irinotecan as Second Line Treatment of SCLCtreatmentNot Availableunknown_status
NCT02748889
Carboplatin Plus Etoposide With or Without MPDL3280A in Untreated Extensive Stage Small Cell Lung Cancertreatment1 / 2terminated
NCT02069158
Dose Finding Study Of PF-05212384 With Paclitaxel And Carboplatin In Patients With Advanced Solid Tumortreatment1completed
NCT05740566
Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancertreatment3active_not_recruiting
NCT04285866
Spanish Real World Data on Patients Treated With Durvalumab After Chemoradiotherapy.Not AvailableNot Availablecompleted
NCT02580994
Pembrolizumab in Untreated Extensive SCLCtreatment2completed
NCT02715102
Circulating Tumor DNA in Patients at High Risk for Lung CancerNo drug interventionsNot AvailableNot Availableterminated
NCT00580320
Safety Study of Dacarbazine and Bortezomib in Melanoma and Soft Tissue Sarcomatreatment1completed
NCT04802174
Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High-Grade Neuroendocrine Cancerstreatment1 / 2recruiting
NCT04826341
A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitorstreatment1 / 2recruiting
NCT05130255
GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2No drug interventionstreatment1recruiting
NCT05546268
Study of Oral MRT-2359 in Selected Cancer Patientstreatment1 / 2recruiting
NCT05655598
TAS-116 Plus Palbociclib in Breast and Rb-null Cancertreatment1withdrawn
NCT06021483
Observational Study to Evaluate the Safety and Efficacy of Zepzelca™ InjectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT06179069
A Study of ZL-1310 in Subjects With Small Cell Lung Cancertreatment1recruiting
NCT06616532
PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancertreatment3not_yet_recruiting
NCT04677361
Feasibility Study on Expandion of MILs From NSCLC and SCLC Patients and Infusion With Pembrolizumabtreatment0withdrawn
NCT05026593
A Study of IBI110 in Combination With Sintilimab and Chemotherapy in Patients With Untreated Extensive-Stage Small Cell Lung Cancertreatment1completed
NCT00346385
BB-10901 in Treating Patients With Relapsed or Refractory Solid Tumorstreatment1completed
NCT02611024
Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumorstreatment1 / 2recruiting
NCT01713296
Pazopanib in Relapsed and Refractory Small Cell Lung Cancertreatment2completed
NCT01797874
Pazopanib Maintenance for SCLCtreatment2completed
NCT06441344
Toripalimab Plus Anlotinib for the Maintenance of Extensive Stage Small Celltreatment3not_yet_recruiting
NCT02734004
A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.treatment1 / 2active_not_recruiting
NCT05879068
A Study of PM8002 in Combination With Chemotherapy in Patients With SCLCtreatment2recruiting
NCT05844150
A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLCtreatment2 / 3recruiting
NCT00046787
Efficacy and Safety Study of OSI-211 (Liposomal Lurtotecan) to Treat Recurrent Small Cell Lung Cancertreatment2completed
NCT03575793
A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancertreatment1 / 2active_not_recruiting
NCT01829971
A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal InjectionNo drug interventionstreatment1terminated
NCT03297788
Whole Brain Radiation Therapy Alone vs. Radiosurgery for SCLC Patients With 1-10 Brain MetastasesNo drug interventionstreatmentNot Availablecompleted
NCT03428607
Study of AZD6738 and Olaparib Combination Therapy in Relapsed Small Cell Lung Cancer Patients [SUKSES-N2]treatment2completed
NCT06475209
Adebrelimab + Apatinib in SCLC Maintenance Therapytreatment2recruiting
NCT06116019
Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS)No drug interventionsNot AvailableNot Availablerecruiting
NCT04684017
Anlotinib Plus Etoposide and Carboplatin as First-line Treatment for Extensive-stage Small Cell Lung Cancertreatment2unknown_status
NCT00522639
Predictive Value of FDG-PET-CT Scans for Patients With Lung Cancer Receiving Concurrent Chemo-RadiationNo drug interventionsdiagnostic3terminated
NCT04750239
Safety and Clinical Activity of Nivatrotamab in Relapsed/Recurrent Metastatic Small-cell Lung Cancertreatment1 / 2terminated
NCT04686682
A First-in-Human, JAB-8263 in Adult Patients With Advanced TumorsNo drug interventionstreatment1 / 2recruiting
NCT06534762
Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Studytreatment2recruiting
NCT02990780
Accelerated Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LS-SCLCNo drug interventionstreatment3unknown_status
NCT03244904
Next-generation Sequencing of Small Cell Lung Cancer to Identify Susceptibility Gene and to Assess TreatmentNo drug interventionsNot AvailableNot Availableunknown_status
NCT06479811
[212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancerstreatment1not_yet_recruiting
NCT02688894
The Molecular Screening Study for the Umbrella Trial (SUKSES) in Relapsed Small Cell Lung Cancer Patients [SUKSES-S]No drug interventionsNot AvailableNot Availablerecruiting