Recessive Dystrophic Epidermolysis Bullosa (DBCOND0064204)

Identifiers

Synonyms

Recessive dystrophic epidermolysis bullosa / Hallopeau-Siemens Disease / Recessive dystrophic epidermolysis bullosa (disorder) / Epidermolysis bullosa, unspecified / Epidermolysis Bullosa / Epidermolysis bullosa (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04177498	Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC	Rigosertib	treatment	0	recruiting
NCT05944250	A Pilot Study to Evaluate a Temporary Skin Substitute (Spincare® Matrix) for Wound Healing in RDEB Patients	No drug interventions	treatment	Not Available	active_not_recruiting
NCT05143190	Extension Study to PTR-01-002 (A Study in Recessive Dystrophic Epidermolysis Bullosa (RDEB) Patients Previously Treated With PTR-01)	PTR-01	treatment	2	completed
NCT04917887	Long-Term Follow-up Protocol	No drug interventions	Not Available	Not Available	recruiting
NCT03529877	Allogeneic ABCB5-positive Stem Cells for Treatment of Epidermolysis Bullosa	Skin-derived ABCB5-positive Mesenchymal Stem cells	treatment	1 / 2	completed
NCT05725018	EB-101 Treatment for New and Previously Treated Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)	Prademagene zamikeracel	treatment	3	recruiting
NCT04285294	Molecular Signatures of Cutaneous Squamous Cell Carcinoma During Recessive Dystrophic Epidermolysis Bullosa	No drug interventions	Not Available	Not Available	unknown_status
NCT04491604	Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB	Beremagene geperpavec	treatment	3	completed
NCT01874769	Study of Immune Tolerance and Capacity for Wound Healing of Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)	No drug interventions	Not Available	Not Available	unknown_status
NCT04599881	A Study of PTR-01 in Recessive Dystrophic Epidermolysis Bullosa	PTR-01	treatment	2	completed
NCT03752905	A Phase 1/2 Trial of PTR-01 in Adult Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)	PTR-01	treatment	1 / 2	completed
NCT04213261	A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa	Dabocemagene autoficel	treatment	3	active_not_recruiting
NCT03392909	Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB)	Gentamicin	treatment	1 / 2	recruiting
NCT02984085	Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With RDEB.	No drug interventions	treatment	1 / 2	terminated
NCT04227106	Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)	Prademagene zamikeracel	treatment	3	completed
NCT02493816	Safety Study of Gene-modified Autologous Fibroblasts in Recessive Dystrophic Epidermolysis Bullosa	No drug interventions	treatment	1	completed
NCT02698735	Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) Nonsense Mutation Patients	Gentamicin	treatment	1 / 2	completed
NCT04520022	Safety and Effectiveness Study of Allogeneic Umbilical Cord Blood-derived Mesenchymal Stem Cell in Patients With RDEB	No drug interventions	treatment	1 / 2	completed
NCT04917874	A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa	Beremagene geperpavec	treatment	3	completed
NCT03012191	Gentamicin for RDEB	Gentamicin	treatment	1 / 2	completed
NCT02323789	Mesenchymal Stromal Cells in Adults With Recessive Dystrophic Epidermolysis Bullosa	Human Umbilical Cord Mesenchymal Stem Cells	other	1 / 2	unknown_status
NCT03632265	Study of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa	Prademagene zamikeracel	treatment	3	not_yet_recruiting