Rigosertib

DB12146InvestigationalSmall molecule

Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.

Chemical structure of Rigosertib
Formula / weight
C21H25NO8S · 451.49 g/mol (avg)
Code names
ON-01910

Resolves to

Compound
UNII67DOW7F9GLCAS592542-59-1ChEMBLCHEMBL1241855ChEBI145417PubChem6918736
Structure
InChIKeyOWBFCJROIKNMGD-BQYQJAHWSA-NSMILESCOC1=CC(OC)=C(\C=C\S(=O)(=O)CC2=CC=C(OC)C(NCC(O)=O)=C2)C(OC)=C1
Targets
P48736PIK3CGP53350PLK1

What you can answer from here — as of September 12, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
39Drug interactionsStructured to mechanism, not free text
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27Clinical trialsPhase, status and sponsor resolved per trial
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4+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Rigosertib, and which of those have an active Phase 3 trial?

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