Homozygous Familial Hypercholesterolaemia (HoFH)

Homozygous Familial Hypercholesterolaemia (HoFH) is the indication for 10 drugs in DrugBank. It is covered by 20 curated, structured indications.

Also known as
Homozygous Familial Hypercholesterolemia · Familial Hypercholesterolemia - Homozygous · Homozygous Familial Hypercholesterolemia (HoFH) · Homozygous Familial Hypercholesterolemia HoFH · HoFH

Resolves to

Vocabularies
MeSHM000746765ICD-10E78.00SNOMED CT238078005MedDRA10017342UMLSC0342881

What you can answer from here — as of October 23, 2026

10Indicated drugsWith each drug's targets and mechanism
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20Structured indicationsPopulation, line of therapy, route and combination as fields, not prose
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58Clinical trialsPhase, status and sponsor resolved per trial
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2Drugs reporting it as an adverse effectWith incidence where the label states it
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Which approved drugs for Homozygous Familial Hypercholesterolaemia (HoFH) share a target, and which companies have late-stage candidates against it?

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