- Anti-Bacterial Agents
- Accession Number
Substances produced by microorganisms that can inhibit or suppress the growth of other microorganisms.
- ATC Classification
Drug Drug Description Gramicidin D A bactericidal antibiotic used in the treatment of dermatological and ophthalmic infections. Erythromycin A macrolide antibiotic used to treat and prevent a variety of bacterial infections. Cycloserine A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI). Capreomycin An aminoglycoside antibiotic used as an adjunct drug in tuberculosis. Framycetin An aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus. Oxytetracycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Rifabutin An antibiotic used to treat mycobacterium avium complex disease in patients with HIV. Bacitracin A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Benzylpenicillin A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. Streptomycin An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. Candicidin Used in the topical treatment of vulvovaginal candidiasis. Rifapentine An antibiotic agent used in the treatment of pulmonary tuberculosis. Paromomycin An aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma. Fusidic acid A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Dihydrostreptomycin Dihydrostreptomycin is an antibiotic. Micronomicin Micronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina. Tyrothricin A topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections. Carfecillin Not Annotated Mepartricin Not Annotated Neomycin An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body. Azithromycin A macrolide antibiotic used to treat a variety of bacterial infections. Moxifloxacin A fluoroquinolone antibiotic used to treat various bacterial infections. Mupirocin An antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes. Chloramphenicol A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. Ciprofloxacin A second generation fluoroquinolone used to treat various susceptible bacterial infections. Tobramycin An aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections. Tetracycline An antibiotic used to treat a wide variety of susceptible infections. Gentamicin An aminoglycoside used to treat a wide variety of aerobic infections in the body. Minocycline A tetracycline analog used to treat a wide variety of infections in the body. Gatifloxacin A fourth generation fluoroquinolone used to treat a wide variety of infections in the body. Norfloxacin A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine. Ofloxacin An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract. Clindamycin A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria. Kanamycin An aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. Amphotericin B An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis. Natamycin A macrolide antifungal used to treat fungal infections of the eye. Daptomycin A cyclic lipopeptide antibiotic used to treat complicated skin and skin structure infections by susceptible Gram-positive bacteria and bacteremia due to Staphylococcus aureus. Cefotiam For treatment of severe infections caused by susceptible bacteria. Aminosalicylic acid An aminosalicylate drug used to induce remission in ulcerative colitis. Dapsone A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Cefmenoxime Used to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria. Cefmetazole For the treatment of infections caused by susceptible organisms. Flucloxacillin A narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA). Ertapenem A carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms. Piperacillin A penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam susceptible, β-lactamase generating strains of several bacteria. Ethambutol An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB). Pyrazinamide An antituberculosis agent used as a component of tuberculosis (TB) treatment. Aztreonam A beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. Grepafloxacin A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections. Ampicillin A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. Phenoxymethylpenicillin A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues. Cefpiramide For treatment of severe infections caused by susceptible bacteria such as P. aeruginosa. Ceftazidime An injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others. Loracarbef Used to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,... Cefalotin A broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract. Enoxacin For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria... Amikacin An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria. Dicloxacillin A penicillin used to treat penicillinase-producing bacterial infections that are susceptible to the drug. Pefloxacin For the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract. Cefotaxime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Vancomycin A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections. Cefdinir A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Cephalexin A first generation cephalosporin used to treat certain susceptible bacterial infections. Carbenicillin For the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria. Linezolid An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. Nafcillin A penicillin derivative antibiotic used to treat susceptible staphylococcal infections. Ethionamide A second line antitubercular agent used to treat tuberculosis when other treatments have failed. Cefixime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Cephaloglycin For treatment of severe infections caused by susceptible bacteria. Oxacillin A penicillin antibiotic used to treat a number of susceptible bacterial infections. Meropenem A carbapenem antibiotic used to treat a wide variety of infections in the body. Clavulanic acid A beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics. Roxithromycin Used to treat respiratory tract, urinary and soft tissue infections. Nalidixic acid A quinolone antibiotic used to treat urinary tract infections. Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Fosfomycin A broad spectrum antibiotic used to treat uncomplicated urinary tract infections. Cefaclor A second generation cephalosporin used to treat a wide variety of infections in the body. Clofazimine A riminophenazine antimycobacterial used to treat leprosy. Sirolimus An immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. Spectinomycin An aminocyclitol antibiotic used to treat susceptible strains of Neisseria gonorrhoeae. Ceforanide For the treatment of infections caused by susceptible organisms. Mezlocillin Used to treat serious gram–negative infections of the lungs, urinary tract, and skin. Dirithromycin For the treatment of the following mild-to-moderate infections caused by susceptible strains of microorganisms: acute bacterial exacerbations of chronic bronchitis, secondary bacterial infection of acute bronchitis, community-acquired pneumonia, pharyngitis/tonsilitis, and... Netilmicin An aminoglycoside used to treat a wide variety of infections in the body. Telithromycin An ketolide used to treat community acquired pneumonia of mild to moderate severity. Lomefloxacin A fluoroquinolone used to prevent and treat a wide variety of infections in the body. Cyclacillin For the treatment of bacterial infections caused by susceptible organisms. Thalidomide A medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum. Rifampicin An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. Novobiocin For the treatment of infections due to staphylococci and other susceptible organisms Amoxicillin A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. Azlocillin For the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae. Cefditoren A broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract. Cefuroxime A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo. Levofloxacin A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague. Cefapirin For treatment of infections caused by susceptible bacteria. Cefadroxil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis. Cloxacillin An antibiotic agent used for the treatment of beta-hemolytic streptococcal and pneumococcal infections as well as staphylococcal infections. Cefprozil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections. Gemifloxacin A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria. Amdinocillin Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms. Sparfloxacin For the treatment of adults with the following infections caused by susceptible strains microorganisms: community-acquired pneumonia (caused by Chlamydia pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, or Streptococcus... Clarithromycin A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. Ceftriaxone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract. Chloroxine An antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp. Josamycin For the treatment of bacterial infections. Cefamandole A beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections. Cefazolin A broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract. Cefonicid For the treatment of bacterial infections caused by susceptible microorganisms. Cefoperazone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts. Cefotetan An antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections. Cefoxitin A semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection. Ceftizoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea. Cefradine A first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues. Quinupristin An antibiotic agent used in the treatment of serious vancomycin-resistant Enterococcus faecium bacteremia as well as complicated skin and skin structure infections. Temafloxacin For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections. Cefepime A fourth-generation cephalosporin antibiotic used in the treatment of various bacterial infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections. Cefacetrile Cefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections. Ceftibuten A third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis. Cefpodoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis. Imipenem A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. Bacampicillin An ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections. Meticillin Used to treat infections caused by susceptible Gram-positive bacteria, particularly beta-lactamase-producing organisms such as Staphylococcus aureus that would otherwise be resistant to most penicillins. Pivampicillin An ampicillin prodrug used to treat a variety of infections. Pivmecillinam A prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs). Ticarcillin A beta lactam antibiotic used to treat a variety of infections in the body. Lincomycin An antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate. Virginiamycin M1 For the treatment of bacterial infections. Dalfopristin An antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes. Maltotetraose Not Available GE-2270A Not Available Ubenimex An adjuvant therapy used for acute and chronic myelonous leukemia, lung cancer and nasopharyngeal cancer. It is also used to treat hypercholesterolaemia. Ribostamycin A broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine. Aurodox Aurodox is an antibiotic obtained from a streptomyces variant considered as possibly effective against streptococcus pyogenes infections. It may promote growth in poultry. Latamoxef Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,... Apramycin For the treatment of bacterial infections in animals. Oritavancin An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria. Ceftobiprole A cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria. Rifalazil Investigated for use/treatment in atherosclerosis, bacterial infection, and peripheral vascular disease. Ramoplanin For the treatment of bacterial infections. Spiramycin A macrolide antimicrobial agent used in the treatment of various bacterial infections. Teicoplanin For the treatment of bacterial infections caused by susceptible microorganisms. Garenoxacin Investigated for use/treatment in bacterial infection. Dalbavancin An antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria. Telavancin An antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia. Cethromycin A ketolide antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and atypical bacteria that may be useful for treating several conditions including community-acquired pneumonia, inhalation anthrax, plague, and tularemia. Squalamine Investigated for use/treatment in ovarian cancer, lung cancer, and macular degeneration. Viomycin Viomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis. Brefeldin A A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity. Anisomycin Anisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis. Chloramphenicol succinate A broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains. Thiamphenicol Not Available Bedaquiline A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB). Enviomycin Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin. Cefaloridine Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH. Tedizolid phosphate An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections. Cefminox Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan. Chlortetracycline The first tetracycline antibiotic most commonly used for veterinary purposes. Kitasamycin Kitasamycin is a macrolide antibiotic derived from Streptomyces kitasatoensis. Carindacillin A penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA. Procaine benzylpenicillin A local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Avilamycin Not Annotated Bambermycins Bambermycins are antibiotic complexes which are retrieved from the organism, Streptomyces bambergiensis. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics... Efrotomycin Not Annotated Florfenicol Florfenicol is a fluorinated synthetic analog of thiamphenicol. Gamithromycin Gamithromycin is an antibiotic used in cattle. Marbofloxacin Marbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary medicine. A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available... Oleandomycin Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus. Roxarsone Roxarsone is an organoarsenic molecule added to poultry feed. The addition of this compound to poultry feed improves weight gain and feed efficiency as well as prevent the growth of... Thiostrepton Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally... Tiamulin Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry. Tilmicosin Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica. Tylosin Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms.... Virginiamycin Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent... Ceftiofur Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active... Hygromycin B Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. Maduramicin Maduramicin is an antiprotozoal agent used in veterinary medicine as prophylaxis against coccidiosis. It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra. Salinomycin Not Annotated Isatoic anhydride Not Available Epetraborole Epetraborole has been used in trials studying the treatment of Infections, Bacterial, Infections, Intestinal, Infections, Urinary Tract, and Community-acquired Infection. Pazufloxacin Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol). Prulifloxacin Prulifloxacin has been investigated for the treatment of Urinary Tract Infection. Lanopepden Lanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases, Infectious, and Skin Infections, Bacterial. Sultamicillin Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD). Nadifloxacin Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris. Sisomicin Sisomicin has been used in trials studying the treatment of Pyoderma. Protionamide Prothionamide has been used in trials studying the treatment of MDR-TB and HIV Infections. Amithiozone Amithiozone has been used in trials studying the treatment of Mycobacterium Avium-intracellulare Infection. Tunicamycin Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes. One member of this family is the enzyme GlcNAc phosphotransferase (GPT), which catalyzes... Troleandomycin For the treatment of bacterial infection. Sitafloxacin Not Annotated Cefatrizine Not Annotated Dibekacin Dibekacin is an aminoglycoside antibiotic marketed in Japan . Miocamycin Miocamycin is a macrolide type antimicrobial . This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia . It has shown to... Epicillin Not Annotated Midecamycin A macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria. Cefodizime A broad-spectrum, third-generation cephalosporin used to treat serious infections caused by susceptible bacteria. Cefsulodin Not Annotated Cefetamet Not Annotated Isepamicin Not Annotated Oxolinic acid Not Annotated Propicillin Not Annotated Bekanamycin Not Annotated Cefpirome Not Annotated Sulbenicillin Not Annotated Pristinamycin Not Annotated Decamethoxine Not Annotated Sulfamethoxypyridazine Not Annotated Cefazedone Not Annotated Talampicillin Not Annotated Ceftezole Not Annotated Pipemidic acid Not Annotated Metampicillin Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the... Clinafloxacin Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of... Rifaximin A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults. Fidaxomicin A macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection. Fusafungine Fusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections. Azidamfenicol Not Annotated Sulfacetamide A corticosteroid used to treat inflammatory ocular conditions and acne vulgaris. Metronidazole A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. Retapamulin A topical antibiotic agent used for the treatment of impetigo caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes. Besifloxacin A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis. Finafloxacin Finafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1... Ozenoxacin A quinolone antibiotic used to treat impetigo caused by susceptible bacteria. Solithromycin Investigated for the treatment of community-acquired pneumonia (CAP). Flurithromycin Not Annotated Rokitamycin Not Annotated Everolimus A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies. Epothilone D Investigated for use/treatment in colorectal cancer, lung cancer, breast cancer, solid tumors, and prostate cancer. Patupilone Investigated for use/treatment in ovarian cancer, lung cancer, brain cancer, breast cancer, and gastric cancer. 6-Deoxyerythronolide B Not Available Ixabepilone A microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines. KOS-1584 Investigated for use/treatment in solid tumors. Ridaforolimus Investigated for use/treatment in solid tumors, sarcoma, cancer/tumors (unspecified), endometrial cancer, prostate cancer, and bone metastases. Temsirolimus A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR. AVE9633 Investigated for use/treatment in leukemia (myeloid). Coltuximab ravtansine Investigated for use/treatment in lymphoma (non-hodgkin's). Mitemcinal Investigated for use/treatment in gastroparesis and irritable bowel syndrome (IBS). Carbomycin Carbomycin, also called magnamycin, is crystalline macrolide antibiotic. This antibacterial is obtained from Streptomyces halstedii and it presents a large inhibitory effect against Gram-positive bacteria and some Mycoplasma strains. The... Doramectin Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in... Eprinomectin Not Annotated Selamectin Selamectin is a topical parasiticide and antihelminthic used on dogs and cats to treat and prevent infections of heartworms, fleas, ear mites, sarcoptic mange, and certain types of ticks in... Tildipirosin Tildipirosin is a veterinary antibiotic. Tylvalosin Not Annotated Bryostatin 1 Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease. Lorvotuzumab mertansine Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others. Epofolate Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. Sagopilone Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is... Mirvetuximab Soravtansine Mirvetuximab Soravtansine has been used in trials studying the treatment of Ovarian cancer, Endometrial Cancer, Fallopian tube cancer, Epithelial Ovarian Cancer, and Primary Peritoneal Cancer, among others. Cefroxadine Was used for the treatment of bacterial infections. Cefbuperazone Not Annotated Ceftaroline fosamil An antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. Cefcapene Not Annotated Cefozopran Not Annotated Benzylpenicilloyl polylysine A penicillin derivative used to determine penicillin allergies. Azidocillin For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including... Penamecillin Not Annotated Aspoxicillin Not Annotated Biapenem Biapenem has been used in trials studying the treatment of Bacterial Infections. Doripenem An antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections. Technetium Tc-99m ciprofloxacin Investigated for use/treatment in infectious and parasitic disease (unspecified). Orbifloxacin Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs. Sarafloxacin Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada. Difloxacin Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced... Trovafloxacin An antibiotic used to treat gonorrhea and chlamydia. Rosoxacin For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Cinoxacin For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and... Fleroxacin Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. Nemonoxacin Investigated for use/treatment in bacterial infection and pneumonia. Flumequine Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections. Rufloxacin Rufloxacin is a quinolone antibiotic. Sulfamethoxazole An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Silver sulfadiazine A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns. Flomoxef Flomoxef has been used in trials studying the treatment of Urinary Tract Infection. Isoniazid An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. Geneticin Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both... Gentamicin C1a Not Available Neamine Not Available Arbekacin Arbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA). Puromycin Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting... Plazomicin An aminoglycoside antibiotic used to treat complicated urinary tract infections. Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Lasalocid Lasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of Streptomyces lasaliensis. Narasin Narasin is an agent with coccidiostatic and antibacterial properties. Sulfameter Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. Temocillin Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. Nigericin A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed) Valinomycin A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately... Mafenide An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Doxycycline A tetracycline antibiotic used to treat a wide variety of bacterial infections. Lymecycline A tetracycline antibiotic used for the treatment of acne vulgaris and other susceptible infections. Tigecycline A glycylcycline antibiotic used to treat a number of susceptible bacterial infections. Demeclocycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Metacycline For the treatment of acute bacterial exacerbations of chronic bronchitis Rolitetracycline A broad-spectrum tetracycline antibiotic used in cases needing high concentrations or when oral administration is impractical. Penimepicycline Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification... Tedizolid An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections. Rifamycin An antibacterial used to treat traveler's diarrhea. Ceftolozane A cephalosporin antibiotic used to treat complicated intra-abdominal infections in combination with metronidazole, complicated urinary tract infections, and hospital-acquired pneumonia. Acetyl sulfisoxazole Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the... Delafloxacin A fluoroquinolone antibiotic used to treat skin and skin structure infections. Pirlimycin Pirlimycin hydrochloride is an antibiotic belonging to the lincosamide class. Often marketed as Pirsue, this drug is used to treat mastitis in cattle. Clomocycline For the treatment and management of Brucellosis, mycoplasma infection, acne vulgaris, chlamydial infection;Chronic bronchitis Sarecycline A tetracycline antibiotic used to treat inflammatory lesions of non-nodular moderate to severe acne vulgaris. Omadacycline A tetracycline antibiotic used to treat community acquired bacterial pneumonia. Radezolid Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others. Meclocycline Currently under investigation for the topical treatment of ulcerative oral mucositis Cefamandole nafate Not Annotated Ceftobiprole medocaril Ceftobiprole medocaril is a ceftobiprole prodrug. Polymyxin B A polymyxin antibiotic used to treat a wide variety of infections in the body. Eravacycline A tetracycline antibiotic used to treat complicated intra-abdominal infections. 25-desacetylrifapentine 25-desacetylrifapentine is under investigation in clinical trial NCT00023387 (TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine). Pheneticillin Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally. Hetacillin Hetacillin is a beta-lactam antibiotic prodrug used to treat bacterial infections. In the body it gets converted to ampicillin. Clometocillin Not Annotated Mycophenolate mofetil An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants. Nitrofurantoin An antibiotic used to treat urinary tract infections. Tinidazole A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis. Mycophenolic acid An immunosuppressant used to prevent organ transplant rejections. Fosmidomycin Not Available Acetic acid An antimicrobial agent used to treat susceptible infections of the external auditory canal. Streptolydigin Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci. Methenamine A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy. Enrofloxacin Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant... Tulathromycin A Tulathromycin is a macrolide antibiotic used to treat bovine respiratory disease in cattle and swine respiratory disease in pigs. It is marketed by Pfizer Inc. under the tradename Draxxin. LCB01-0371 Lcb01 0371 is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study). Malacidin A Malacidin A is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . Malacidin B Malacidin B is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . Murepavadin Murepavadin is under investigation in clinical trial NCT02110459 (Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment). Umirolimus Not Annotated Echinomycin Echinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis. Cefiderocol A cephalosporin antibiotic used in complicated urinary tract infections. Amphomycin Not Annotated Pradofloxacin Pradofloxacin is a 3rd generation fluoroquinolone antibiotic developed by Bayer HealthCare AG, Animal Health GmBH. It was approved by the European Commission in April 2011 for bacterial infections in dogs... Ala-geninthiocin Ala-geninthiocin is a novel thiopeptide antibacterial compound derived from marine Streptomyces species. It has exhibited potent in vitro activity against gram-positive bacteria including Staphylococcus aureus, Bacillus subtilis, Mycobacterium smegmatis, and... Sulbactam pivoxil Not Annotated Josamycin propionate Not Annotated Nafithromycin Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP). Pexiganan Pexiganan is under investigation in clinical trial NCT01594762 (Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers). Indatuximab ravtansine Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma). Nanoparticle Epirubicin Nanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma). Carrimycin Not Available
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