Rolicyclidine

DB01549ExperimentalIllicitSmall molecule

Rolicyclidine (PCPy) is classified as a dissociative anesthetic agent. It also has hallucinogenic and sedative properties. Because of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to...

Mechanism: Rolicyclidine works primarily as an NMDA receptor antagonist, which blocks the activity of the NMDA Receptor.
Curator reviewed
Primary indication: Rolicyclidine has anesthetic properties and can induce a sedative effect.Curator reviewed
Formula / weight: C₁₆H₂₃N · 229.3605 g/mol (avg)
Also known as: PCPy
Code names: DEA No. 7458

Resolves to

Compound

UNII183O9O9JE3CAS2201-39-0ChEMBLCHEMBL1719398ChEBI60805PubChem62436

Structure

InChIKeyFYOWWXMGDATDQY-UHFFFAOYSA-NSMILESC1CCN(C1)C1(CCCCC1)C1=CC=CC=C1

Targets

Q8TCU5GRIN3AP14416DRD2

What you can answer from here — as of September 20, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Rolicyclidine, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account