Accession Number

A family of hexahydropyridines.

DrugDrug Description
ArgatrobanA synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
TerfenadineAn antihistamine for the treatment of allergy symptoms.
MinoxidilAn antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage.
AminoglutethimideAn adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome.
TrihexyphenidylAn antispasmodic drug used as an adjunct drug in the management of parkinsonism and as a treatment for extrapyramidal symptoms caused by drugs affecting the central nervous system (CNS).
MiglustatA glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
MethylphenidateA stimulant used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
CyproheptadineA combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome.
MeperidineAn opioid agonist with analgesic and sedative properties used to manage severe pain.
LoratadineA second generation antihistamine used to manage the symptoms of allergic rhinitis.
LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
MiglitolAn oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
CisaprideA medication used to treat heartburn associated with GERD.
SufentanilAn opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain.
ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
AzatadineAn H1 receptor antagonist used to treat perennial and allergic rhinitis as well as eustachian tube congestion.
AlfentanilAn opioid agonist used to induce and maintain anesthesia, as well as an analgesic.
BiperidenA muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs.
FentanylAn opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management.
LoperamideA long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
TiagabineAn antiepileptic used to treat partial seizures.
AnileridineAn opioid analgesic used to treat moderate to severe pain.
KetotifenA histamine H1 receptor blocker and mast cell stabilizer used to treat mild atopic asthma and allergic conjunctivitis.
FexofenadineA selective H1-antagonist for the symptomatic treatment of seasonal allergic rhinitis and chronic idiopathic urticaria.
MepivacaineA local anesthetic used for local or regional analgesia or anesthesia.
DesloratadineA second generation tricyclic antihistamine used to treat seasonal and non seasonal allergic rhinitis, pruritus, and urticaria.
ThalidomideA medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum.
PerhexilineFor the management of severe angina pectoris.
DiphenoxylateAn antidiarrheal medication used with atropine to manage diarrhea.
MethyprylonFor the treatment of insomnia.
DomperidoneA dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
FlecainideA class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT).
GlutethimideFor the treatment of insomnia.
DesmethylprodineDesmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine. It has been listed as a Schedule I controlled drug in the United States, and thus...
DifenoxinAn antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.
TenocyclidineBecause of its high affinity for the phencyclidine binding site on the NMDA receptor, the 3H radiolabelled form of tenocyclidine is widely used in research into NMDA receptors.
CarfentanilCarfentanil is similar (but more potent) to the opioid analgesic fentanyl. It is used as a tranquilizer for large animals.
1-PiperidinocyclohexanecarbonitrileNot Available
RolicyclidineRolicyclidine has anesthetic properties and can induce a sedative effect.
α-Methylfentanylα-Methylfentanyl is an analog of fentanyl with opioid analgesic properties.
OhmefentanylOhmefentanyl is an extremely potent opioid analgesic drug which selectively binds to the µ-opioid receptor. The Chinese have recorded ohmefentanyl as having a potency that is 6,300 times morphine. Ohmefentanyl...
3-Methylfentanyl3-Methylfentanyl is an opioid analgesic and is an analog of the potent opioid, fentanyl. 3-Methylfentanyl is one of the most powerful opioid drugs sold illegally and is estimated to be...
DuvoglustatAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
PhencyclidineA hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like...
FluspirileneAn antipsychotic agent used in the treatment of schizophrenia.
MigalastatAn alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
AmonafideInvestigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
LobelineInvestigated for use/treatment in addictions.
DexmethylphenidateA norepinephrine-dopamine reuptake inhibitor used in the treatment of ADHD in conjunction with other therapies.
KetobemidoneFor the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures.
Nipecotic acidNot Annotated
PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
IndoraminIndoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
DexetimideA muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.
3-Allylfentanyl3-allyfentanyl is a fentanyl derivative opioid that can cause itching, nausea and serious respiratory depression. Fentanyl and its analogs have killed thousands of people around the world as drugs of...
BrifentanilBrifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. This drug is classified as an opioid analgesic and was developed in the early 1990s. The effects...
LofentanilLofentanil is an analog of fentanyl and is one of the most potent opioids available today. It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly more...
MirfentanilMirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor. At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in...
R-30490R-30490 is an opioid related to carfentanil used as an animal tranquilizer. It was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study of fentanly and its...
BenzylfentanylBenzylfentanyl (R-4129) is a fentanyl analog opioid that was on the list of Schedule I drugs in America in 1985 due to its structural similarity to fentanyl. In 2010 it...
RupatadineA selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis.
HT-0712BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).
Antineoplaston A10Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
GemigliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.
KetanserinKetanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.
PiritramideA synthetic opioid used in the treatment of severe pain.
RitanserinRitanserin has been used in trials studying the treatment of Cocaine-Related Disorders.
AlphaprodineNot Annotated
PhenglutarimideNot Annotated
MetopimazineNot Annotated
PhenoperidineNot Annotated
PenfluridolNot Annotated
ClopamideClopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
Loperamide oxideNot Annotated
TicaloprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
IcaridinIcaridin is indicated for use to repel insects, such as mosquitoes, biting flies, ticks, chiggers, and fleas, via topical use or over clothing .
AfegostatNot Available
AvadomideAvadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma).
Carfentanil, C-11Carfentanil, C-11 is under investigation in clinical trial NCT01899170 (Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain).
DonepezilAn acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia.
RemifentanilAn opioid analgesic used in anesthesia.
RimonabantFor use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m2, or patients wih a BMI greater than 27 kg/m2 with associated...
CrizotinibA receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
ButyrfentanylA methylated fentanyl analog with no clinical indications but is commonly used as a recreational drug.
LucerastatLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
AvacopanAvacopan is under investigation in clinical trial NCT02994927 (A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis).
SerdexmethylphenidateA prodrug of the CNS stimulant dexmethylphenidate used as a first-line treatment for Attention Deficit Hyperactivity Disorder (ADHD).
NavtemadlinNavtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia).
Drugs & Drug Targets
ArgatrobanCytochrome P450 3A4enzyme
ArgatrobanCytochrome P450 3A5enzyme
ArgatrobanSerum albumincarrier
Argatrobanalpha1-acid glycoproteincarrier
TerfenadineHistamine H1 receptortarget
TerfenadinePotassium voltage-gated channel subfamily H member 2target
TerfenadineCytochrome P450 3A4enzyme
TerfenadineCytochrome P450 2D6enzyme
TerfenadineMuscarinic acetylcholine receptor M3target
TerfenadineCytochrome P450 3A5enzyme
TerfenadineCytochrome P450 3A7enzyme
TerfenadineP-glycoprotein 1transporter
TerfenadineCytochrome P450 2C8enzyme
TerfenadineCytochrome P450 2J2enzyme
TerfenadineMuscarinic acetylcholine receptor M1target
TerfenadineMuscarinic acetylcholine receptor M5target
TerfenadineMuscarinic acetylcholine receptor M4target
TerfenadineMuscarinic acetylcholine receptor M2target
TerfenadineBile salt export pumptransporter
MinoxidilATP-sensitive inward rectifier potassium channel 1target
MinoxidilProstaglandin G/H synthase 1target
MinoxidilUDP-glucuronosyltransferase 1-1enzyme
AminoglutethimideCytochrome P450 19A1target
AminoglutethimideCytochrome P450 2C19enzyme
AminoglutethimideCytochrome P450 3A4enzyme
AminoglutethimideCholesterol side-chain cleavage enzyme, mitochondrialtarget
TrihexyphenidylMuscarinic acetylcholine receptor M1target
TrihexyphenidylMuscarinic acetylcholine receptor M2target
TrihexyphenidylMuscarinic acetylcholine receptor M3target
TrihexyphenidylMuscarinic acetylcholine receptor M4target
TrihexyphenidylMuscarinic acetylcholine receptor M5target
TrihexyphenidylSerum albumincarrier
MiglustatCeramide glucosyltransferasetarget
MethylphenidateSodium-dependent dopamine transportertarget
MethylphenidateSodium-dependent noradrenaline transportertarget
Methylphenidate5-hydroxytryptamine receptor 1Atarget
Cyproheptadine5-hydroxytryptamine receptor 2Atarget
CyproheptadineHistamine H1 receptortarget
CyproheptadineMuscarinic acetylcholine receptor M1target
CyproheptadineMuscarinic acetylcholine receptor M2target
CyproheptadineMuscarinic acetylcholine receptor M3target
Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
Cyproheptadine5-hydroxytryptamine receptor 7target
CyproheptadineUDP-glucuronosyltransferase 2B10enzyme
CyproheptadineUDP-glucuronosyltransferase 1-4enzyme
Cyproheptadine5-hydroxytryptamine receptor 2Btarget
CyproheptadineHistamine H2 receptortarget
CyproheptadineSolute carrier family 22 member 1transporter
CyproheptadineSerum albumincarrier
MeperidineKappa-type opioid receptortarget
MeperidineCytochrome P450 2D6enzyme
MeperidineCytochrome P450 2B6enzyme
MeperidineGlutamate receptor ionotropic, NMDA 1target
MeperidineGlutamate receptor ionotropic, NMDA 2Btarget
MeperidineGlutamate receptor ionotropic, NMDA 2Atarget
MeperidineGlutamate receptor ionotropic, NMDA 2Ctarget
MeperidineGlutamate receptor ionotropic, NMDA 2Dtarget
MeperidineCytochrome P450 2C19enzyme
MeperidineCytochrome P450 3A4enzyme
MeperidineSerum albumincarrier
MeperidineAlpha-1-acid glycoprotein 1carrier
MeperidineMuscarinic acetylcholine receptortarget
MeperidineMu-type opioid receptortarget
MeperidineSodium-dependent dopamine transportertarget
MeperidineSodium-dependent noradrenaline transportertarget
MeperidineSodium-dependent serotonin transportertarget
MeperidineLiver carboxylesterase 1target
MeperidineCytochrome P450 1A2enzyme
MeperidineP-glycoprotein 1transporter
LoratadineHistamine H1 receptortarget
LoratadineCytochrome P450 3A4enzyme
LoratadineCytochrome P450 2C19enzyme
LoratadineCytochrome P450 2D6enzyme
LoratadineCytochrome P450 2C8enzyme
LoratadineP-glycoprotein 1transporter
LoratadinePotassium voltage-gated channel subfamily H member 2target
LoratadineBile salt export pumptransporter
LoratadineCytochrome P450 1A1enzyme
LoratadineCytochrome P450 1A2enzyme
LoratadineCytochrome P450 2B6enzyme
LoratadineCytochrome P450 2C9enzyme
LoratadineCytochrome P450 3A5enzyme
LoratadineUDP-glucuronosyltransferase 2B10enzyme
LoratadineUDP-glucuronosyltransferase 1-1enzyme
LoratadineUDP-glucuronosyltransferase 1-3enzyme
LoratadineUDP-glucuronosyltransferase 2B15enzyme
LenalidomideProstaglandin G/H synthase 2target
LenalidomideTumor necrosis factor ligand superfamily member 11target
LenalidomideProtein cereblontarget
LenalidomideP-glycoprotein 1transporter
MiglitolMaltase-glucoamylase, intestinaltarget
MiglitolPancreatic alpha-amylaseenzyme
MiglitolLysosomal alpha-glucosidasetarget
MiglitolNeutral alpha-glucosidase ABtarget
MiglitolNeutral alpha-glucosidase Ctarget
Cisapride5-hydroxytryptamine receptor 4target
Cisapride5-hydroxytryptamine receptor 3Atarget
CisapridePotassium voltage-gated channel subfamily H member 2target
Cisapride5-hydroxytryptamine receptor 2Atarget
CisaprideCytochrome P450 3A4enzyme
CisaprideCytochrome P450 3A5enzyme
CisaprideCytochrome P450 3A7enzyme
CisaprideCytochrome P450 2A6enzyme
CisaprideCytochrome P450 2B6enzyme
CisaprideCytochrome P450 2C19enzyme
CisaprideCytochrome P450 2C8enzyme
CisaprideCytochrome P450 2C9enzyme
CisaprideCytochrome P450 2D6enzyme
SufentanilMu-type opioid receptortarget
SufentanilDelta-type opioid receptortarget
SufentanilKappa-type opioid receptortarget
SufentanilCytochrome P450 3A4enzyme
ParoxetineSodium-dependent serotonin transportertarget
ParoxetineSodium-dependent noradrenaline transportertarget
Paroxetine5-hydroxytryptamine receptor 2Atarget
ParoxetineCytochrome P450 2D6enzyme
ParoxetineCytochrome P450 2C9enzyme
ParoxetineP-glycoprotein 1transporter
ParoxetineCytochrome P450 2B6enzyme
ParoxetineCytochrome P450 1A2enzyme
ParoxetineCytochrome P450 3A4enzyme
ParoxetineAlpha-1 adrenergic receptorstarget
ParoxetineAlpha-2 adrenergic receptorstarget
ParoxetineBeta adrenergic receptortarget
ParoxetineDopamine D2 receptortarget
ParoxetineHistamine H1 receptortarget
ParoxetineSerotonin Receptorstarget
ParoxetineMuscarinic acetylcholine receptortarget
Paroxetine5-hydroxytryptamine receptor 2Btarget
ParoxetineD(1) dopamine receptortarget
ParoxetineCytochrome P450 2C19enzyme
AzatadineHistamine H1 receptortarget
AzatadineCytochrome P450 3A4enzyme
AlfentanilMu-type opioid receptortarget
AlfentanilCytochrome P450 3A4enzyme
AlfentanilCytochrome P450 3A5enzyme
AlfentanilAlpha-1-acid glycoprotein 1carrier
AlfentanilSerum albumincarrier
AlfentanilCytochrome P450 3A7enzyme
AlfentanilP-glycoprotein 1transporter
BiperidenMuscarinic acetylcholine receptor M1target
BiperidenCytochrome P450 2D6enzyme
FentanylMu-type opioid receptortarget
FentanylDelta-type opioid receptortarget
FentanylCytochrome P450 3A4enzyme
FentanylCytochrome P450 3A7enzyme
FentanylP-glycoprotein 1transporter
FentanylKappa-type opioid receptortarget
FentanylP-glycoprotein 1target
FentanylSerum albumincarrier
Fentanylalpha1-acid glycoproteincarrier
LoperamideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
LoperamideMu-type opioid receptortarget
LoperamideDelta-type opioid receptortarget
LoperamideCytochrome P450 3A4enzyme
LoperamideP-glycoprotein 1transporter
LoperamideKappa-type opioid receptortarget
LoperamideCytochrome P450 2C8enzyme
LoperamideCytochrome P450 2B6enzyme
LoperamideCytochrome P450 2D6enzyme
LoperamideNuclear receptor subfamily 1 group I member 3target
TiagabineSodium- and chloride-dependent GABA transporter 1target
TiagabineCytochrome P450 3A4enzyme
TiagabineUDP-glucuronosyltransferase 1-1enzyme
AnileridineMu-type opioid receptortarget
KetotifenHistamine H1 receptortarget
Ketotifen6-phosphogluconate dehydrogenase, decarboxylatingtarget
KetotifenUDP-glucuronosyltransferase 1-3enzyme
KetotifenUDP-glucuronosyltransferase 1-4enzyme
KetotifenUDP-glucuronosyltransferase 2B10enzyme
FexofenadineHistamine H1 receptortarget
FexofenadineP-glycoprotein 1transporter
FexofenadineSolute carrier organic anion transporter family member 2B1transporter
FexofenadineSolute carrier organic anion transporter family member 1A2transporter
FexofenadineSolute carrier organic anion transporter family member 1B1transporter
FexofenadineSolute carrier organic anion transporter family member 1B3transporter
FexofenadineSolute carrier family 22 member 8transporter
FexofenadineCanalicular multispecific organic anion transporter 1transporter
FexofenadineCanalicular multispecific organic anion transporter 2transporter
FexofenadineSerum albumincarrier
Fexofenadinealpha1-acid glycoproteincarrier
MepivacaineSodium channel protein type 10 subunit alphatarget
DesloratadineHistamine H1 receptortarget
DesloratadineP-glycoprotein 1transporter
ThalidomideTumor necrosis factortarget
ThalidomideNuclear factor NF-kappa-B p105 subunittarget
ThalidomideProstaglandin G/H synthase 2target
ThalidomideCytochrome P450 2C19enzyme
ThalidomideCytochrome P450 2C9enzyme
ThalidomideProstaglandin G/H synthase 1enzyme
ThalidomideProstaglandin G/H synthase 2enzyme
ThalidomideCytochrome P450 3A5enzyme
ThalidomideFibroblast growth factor receptor 2target
ThalidomideProtein cereblontarget
Thalidomidealpha1-acid glycoproteintarget
PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformtarget
PerhexilineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
PerhexilineCytochrome P450 2D6enzyme
PerhexilineCytochrome P450 2B6enzyme
PerhexilineCytochrome P450 3A4enzyme
PerhexilinePotassium voltage-gated channel subfamily H member 2target
DiphenoxylateMu-type opioid receptortarget
DiphenoxylateDelta-type opioid receptortarget
MethyprylonGamma-aminobutyric acid receptor subunit alpha-1target
MethyprylonGABA(A) Receptortarget
DomperidoneDopamine D2 receptortarget
DomperidoneCytochrome P450 3A4enzyme
DomperidoneCytochrome P450 3A5enzyme
DomperidoneCytochrome P450 3A7enzyme
DomperidoneP-glycoprotein 1transporter
DomperidoneCytochrome P450 1A2enzyme
DomperidoneCytochrome P450 2B6enzyme
DomperidoneCytochrome P450 2C8enzyme
DomperidoneCytochrome P450 2D6enzyme
DomperidoneDopamine D3 receptortarget
FlecainideSodium channel protein type 5 subunit alphatarget
FlecainideCytochrome P450 2D6enzyme
FlecainideSodium channel protein type 4 subunit alphatarget
FlecainideCytochrome P450 2C9enzyme
FlecainidePotassium voltage-gated channel subfamily H member 2target
Flecainidealpha1-acid glycoproteincarrier
FlecainideSerum albumincarrier
FlecainideCytochrome P450 1A2enzyme
FlecainideP-glycoprotein 1transporter
FlecainideMultidrug and toxin extrusion protein 1transporter
FlecainideRyanodine receptor 2target
GlutethimideCholesterol side-chain cleavage enzyme, mitochondrialenzyme
GlutethimideGamma-aminobutyric acid receptor subunit alpha-1target
GlutethimideGABA(A) Receptortarget
TenocyclidineGlutamate receptor ionotropic, NMDA 3Atarget
TenocyclidineGlutamate receptor ionotropic, NMDA 3Btarget
TenocyclidineGlutamate receptor ionotropic, NMDA 2Atarget
TenocyclidineGlutamate receptor ionotropic, NMDA 2Ctarget
TenocyclidineGlutamate receptor ionotropic, NMDA 2Btarget
TenocyclidineGlutamate receptor ionotropic, NMDA 2Dtarget
TenocyclidineAlpha-7 nicotinic cholinergic receptor subunittarget
CarfentanilMu-type opioid receptortarget
CarfentanilKappa-type opioid receptortarget
CarfentanilDelta-type opioid receptortarget
RolicyclidineGlutamate receptor ionotropic, NMDA 3Atarget
RolicyclidineDopamine D2 receptortarget
3-MethylfentanylMu-type opioid receptortarget
3-MethylfentanylDelta-type opioid receptortarget
3-MethylfentanylKappa-type opioid receptortarget
DuvoglustatCyclomaltodextrin glucanotransferasetarget
DuvoglustatBeta-glucosidase Atarget
DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DuvoglustatXylose isomerasetarget
PhencyclidineGlutamate receptor ionotropic, NMDA 3Atarget
PhencyclidineSigma non-opioid intracellular receptor 1target
PhencyclidineCytochrome P450 2B6enzyme
FluspirileneDopamine D2 receptortarget
Fluspirilene5-hydroxytryptamine receptor 2Atarget
FluspirileneVoltage-dependent calcium channel gamma-1 subunittarget
FluspirileneCytochrome P450 3A4enzyme
MigalastatAlpha-galactosidase Atarget
MigalastatUDP-glucuronosyltransferase 1-1enzyme
AmonafideDNA topoisomerase 2-alphatarget
AmonafideDNA topoisomerase 2-betatarget
LobelineNeuronal acetylcholine receptor subunit alpha-9target
LobelineNeuronal acetylcholine receptor subunit alpha-10target
LobelineNeuronal acetylcholine receptor subunit alpha-7target
DexmethylphenidateSodium-dependent dopamine transportertarget
DexmethylphenidateSodium-dependent noradrenaline transportertarget
DexmethylphenidateSodium-dependent serotonin transportertarget
KetobemidoneProstaglandin G/H synthase 1enzyme
KetobemidoneCytochrome P450 2C9enzyme
KetobemidoneCytochrome P450 3A4enzyme
KetobemidoneUDP-glucuronosyltransferase 1-9enzyme
KetobemidoneCytochrome P450 2B6enzyme
KetobemidoneCytochrome P450 2C19enzyme
KetobemidoneCytochrome P450 2C8enzyme
KetobemidoneMu-type opioid receptortarget
KetobemidoneKappa-type opioid receptortarget
KetobemidoneDelta-type opioid receptortarget
KetobemidoneNMDA receptortarget
Nipecotic acidProton-coupled amino acid transporter 1transporter
PomalidomideCytochrome P450 1A2enzyme
PomalidomideCytochrome P450 3A4enzyme
PomalidomideP-glycoprotein 1transporter
PomalidomideProtein cereblontarget
PomalidomideTumor necrosis factortarget
PomalidomideProstaglandin G/H synthase 2target
IndoraminAlpha-1A adrenergic receptortarget
RupatadineCytochrome P450 3A4enzyme
RupatadineCytochrome P450 2C9enzyme
RupatadineCytochrome P450 2C19enzyme
RupatadineCytochrome P450 2D6enzyme
RupatadinePlatelet-activating factor receptortarget
RupatadineHistamine H1 receptortarget
Ketanserin5-hydroxytryptamine receptor 2Atarget
Ritanserin5-hydroxytryptamine receptor 2Atarget
RitanserinCytochrome P450 2D6enzyme
PenfluridolCytochrome P450 3A4enzyme
Ticalopride5-hydroxytryptamine receptor 4target
Ticalopride5-hydroxytryptamine receptor 3Atarget
IcaridinOdorant binding proteintarget
AfegostatEndoglucanase 5Atarget
AfegostatBeta-glucosidase Atarget
AfegostatPossible cellulase CelA1 (Endoglucanase) (Endo-1,4-beta-glucanase) (FI-cmcase) (Carboxymethyl cellulase)target
Donepezil5-hydroxytryptamine receptor 2Atarget
DonepezilCytochrome P450 3A4enzyme
DonepezilCytochrome P450 2D6enzyme
DonepezilCytochrome P450 2C9enzyme
DonepezilNitric oxide synthase, braintarget
DonepezilTumor necrosis factor-inducible gene 6 proteintarget
DonepezilInterleukin-1 betatarget
DonepezilNuclear factor NF-kappa-Btarget
DonepezilATP-binding cassette sub-family G member 2transporter
DonepezilNMDA receptortarget
RemifentanilMu-type opioid receptortarget
RemifentanilDelta-type opioid receptortarget
RemifentanilKappa-type opioid receptortarget
RimonabantCannabinoid receptor 1target
RimonabantCytochrome P450 3A4enzyme
RimonabantG-protein coupled receptor 55target
CrizotinibCytochrome P450 3A4enzyme
CrizotinibCytochrome P450 3A5enzyme
CrizotinibP-glycoprotein 1transporter
CrizotinibALK tyrosine kinase receptortarget
CrizotinibHepatocyte growth factor receptortarget
CrizotinibCytochrome P450 2B6enzyme
CrizotinibCytochrome P450 3A Subfamilyenzyme
ButyrfentanylMu-type opioid receptortarget
ButyrfentanylKappa-type opioid receptortarget
ButyrfentanylDelta-type opioid receptortarget
ButyrfentanylCytochrome P450 3A4enzyme
ButyrfentanylCytochrome P450 2D6enzyme
SerdexmethylphenidateSodium-dependent dopamine transportertarget
SerdexmethylphenidateSodium-dependent noradrenaline transportertarget
Serdexmethylphenidate5-hydroxytryptamine receptor 1Atarget