- Accession Number
A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.
Drug Drug Description Peginterferon alfa-2a A modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses. Peginterferon alfa-2b A purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers. Pegaspargase A modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine. Carboprost tromethamine A prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective. Chloramphenicol A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. Chlorphenesin A phenol ether used to treat painful muscular conditions. Felbamate An anticonvulsant used to treat severe epilepsy. Busulfan An alkylating agent used to treat chronic myelogenous leukemia. Dichloralphenazone Dichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing isometheptene and acetaminophen used for the relief of tension... Chloral hydrate A mild hypnotic used for experimental purposes that was previously used for the treatment of insomnia. Propylene glycol A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. 1,4-Butanediol Not Available 2-Ethoxyethanol Not Available 2-Methoxyethanol Not Available Sphingosine An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed) Tromethamine A proton acceptor used for the prevention and correction of metabolic acidosis associated with various clinical conditions, such as cardiac bypass surgery. SP1049C Intended for the treatment of carcinoma of the oesophagus. Lemuteporfin Intended for the treatment of benign prostatic hyperplasia and prostrate disorders. PEG-uricase Investigated for use/treatment in hyperuricemia. LJP 1082 Investigated for use/treatment in autoimmune diseases, strokes, and thrombosis. Maxy-G34 Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics. Pentaerythritol tetranitrate Used for the treatment of angina pectoris . Tyloxapol Tyloxapol is an inhaled surfactant that assists in removing and liquefying and removing bronchopulmonary secretions with mucus and pus. Tyloxapol is administered either through nebulized solution or a stream of... Pegsunercept Investigated for use/treatment in rheumatoid arthritis. Lodoxamide An ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis. Nonoxynol-9 A vaginal spermicide used for the non-hormonal contraception in conjunction with other modes of contraception. Polidocanol A sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity. Bromamphenicol Not Available Chloramphenicol succinate A broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains. Thiamphenicol Not Available Fingolimod A sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19. Peginesatide Peginesatide is used for the treatment of anemia due to chronic kidney disease (CKD) in adult patients on dialysis Certolizumab pegol A tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis. Naloxegol A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. Methoxy polyethylene glycol-epoetin beta A synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease. Florbetapir (18F) A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment. Pegloticase A recombinant uricase used for the treatment of chronic gout in adult patients refractory to conventional therapy. Polyethylene glycol A laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures. Polysorbate 80 It is used as a solubilizer, antimicrobial preservative and disinfectant . Polyethylene glycol 400 An ingredient used in a wide variety of medications, and is not an approved medication. Polyethylene glycol 300 Indicated as a lubricant in over-the-counter ophthalmic solutions to temporarily relieve redness, burning and irritation of the eyes. Polysorbate 20 Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is... Poloxamer 407 Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks,... Phenoxyethanol An antiseptic used as a hand disinfectant or preservative in medications. Poloxamer 188 A medication used to clean wounds. Florfenicol Florfenicol is a fluorinated synthetic analog of thiamphenicol. Poloxalene Ethylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen... Insulin peglispro Not Annotated Treosulfan Treosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood. Safingol Safingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. Secoisolariciresinol Secoisolariciresinol has been used in trials studying the prevention of Breast Cancer. Levodropropizine Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine). Pegamotecan Pegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer. Propatyl nitrate Not Annotated Pentaerithrityl Not Annotated Mephenesin A cresol glyceryl ether used to treat muscle spasticity in Parkinson's and Multiple Sclerosis. Aloglutamol Aloglutamol is an antacid salt of aluminium, gluconic acid, and tris. Proprietary names include Altris, Pyreses, Tasto and Sabro. Dropropizine Not Annotated Nonacog beta pegol A recombinant coagulation Factor IX derivative used to treat hemophilia B. Bronopol An antimicrobial compound used as a biocide and preservative. Tetraglyme Not Annotated Butylene glycol Not Annotated Phytosphingosine Not Annotated Antihemophilic Factor (Recombinant), PEGylated For the management of hemophilia A (congenital factor VIII deficiency) [FDA label], . This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)... Chlorphenesin carbamate Not Annotated Chloramphenicol palmitate Not Annotated Triglyme Triethylene glycol dimethyl ether (also called triglyme) is a glycol ether used as a solvent. Triethylene glycol Not Available Trichloroacetaldehyde Not Available Diglyme Not Available Calaspargase pegol An asparagine specific enzyme used to treat acute lymphoblastic leukemia. Pegargiminase Investigated for use/treatment in melanoma and hepatocellular carcinoma. Peginterferon lambda-1a Peginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs. Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C). Etirinotecan pegol Etirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma). Firtecan pegol Firtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer). Somatropin pegol Somatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083). Lulizumab pegol Lulizumab pegol is under investigation in clinical trial NCT02843659 (Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome). Pegfilgrastim A recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy. Dexketoprofen For short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache . Lipegfilgrastim A medication used to reduce the duration of chemotherapy-induced neutropenia and incidence of febrile neutropenia in cytotoxic chemotherapy. Bempegaldesleukin Bempegaldesleukin is under investigation in clinical trial NCT03729245 (A Study of NKTR-214 in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib... Pegilodecakin Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer). Pegbelfermin Pegbelfermin is under investigation in clinical trial NCT03486899 (A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis). Azidamfenicol Not Annotated Dihydroxyphenylglycine Not Available 1,3-Propanediol Not Available Dapirolizumab pegol Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus). Pegylated synthetic human c-peptide Not Annotated
- Drugs & Drug Targets