Dotarizine

DB06446ExperimentalSmall molecule

Dotarizine is a calcium antagonist used to treat and prevent migraines.

Chemical structure of Dotarizine
Primary indication
Investigated for use/treatment in migraine and cluster headaches.Curator reviewed
Formula / weight
C29H34N2O2 · 442.5925 g/mol (avg)

Resolves to

Compound
UNIIIO7663S6D3CAS84625-59-2ChEMBLCHEMBL2106316ChEBI138033PubChem55285
Structure
InChIKeyLRMJAFKKJLRDLE-UHFFFAOYSA-NSMILESC(CN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1)CC1(OCCO1)C1=CC=CC=C1
Targets
P28223HTR2AP08908HTR1AO00555CACNA1AP28335HTR2C

What you can answer from here — as of March 06, 2025

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1,330Drug interactionsStructured to mechanism, not free text
Sign in
6+ReferencesStructured and connected to the statements they support
Sign in

Which drugs share a target with Dotarizine, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In