5-hydroxytryptamine receptor 2C

BE0000533ProteinHumansHTR2C

G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:12970106, PubMed:18703043, PubMed:19057895, PubMed:29398112, PubMed:7895773). It is acted on by 99 drugs in DrugBank.

Gene name
HTR2C
UniProtKB entry
P28335Swiss-Prot
Cellular location
Cell membrane
Residues / weight
458 residues · 51,805 Da
Also known as
5-HT-1C · 5-HT-2C · 5-HT1C · 5-HT2C · 5-HTR2C

Resolves to

Protein
UniProtP28335UniProt name5HT2C_HUMAN
Gene
HGNCHGNC:5295NCBI Gene3358GenBank338028GeneCardsHTR2C
Pharmacology
IUPHAR/GtoPdb8KEGGhsa:3358
Structure
PDB6BQGPDB6BQHPDB8DPF
Drugs

What you can answer from here — as of September 07, 2019

99DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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321+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 5-hydroxytryptamine receptor 2C, how selective are they, and which programs against it are still in active trials?

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