Indoxyl sulfate

DB07992ExperimentalSmall molecule

Indoxyl sulfate: Overview.

Mechanism: Pharmacologically active on Aryl hydrocarbon receptor
Curator reviewed
Formula / weight: C₈H₇NO₄S · 213.21 g/mol (avg)
Also known as: 3-indolyl hydrogen sulfate · 3-indolyl sulfate · 3-Indoxyl sulfate · 3-Indoxylsulfuric acid · Indican

Resolves to

Compound

UNIIKT0QA88913CAS487-94-5ChEMBLCHEMBL1233636ChEBI43355PubChem10258

Clinical / RWD

RxNorm2463933

Structure

InChIKeyBXFFHSIDQOFMLE-UHFFFAOYSA-NSMILESOS(=O)(=O)OC1=CNC2=CC=CC=C12

Targets

P35869AHR

Transporters

Q4U2R8SLC22A6Q9UNQ0ABCG2Q8TCC7SLC22A8

What you can answer from here — as of July 03, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3TransportersSubstrate / inhibitor direction, not just membership

Listed above

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Indoxyl sulfate, and which of those have an active Phase 3 trial?

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