Milataxel

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DB12334InvestigationalSmall molecule

Milataxel has been used in trials studying the treatment of Mesothelioma.

Mechanism: Milataxel enhances the rate of tubulin polymerization in vitro and causes the bundling of microtubules in cells.
Curator reviewed
Formula / weight: C₄₄H₅₅NO₁₆ · 853.915 g/mol (avg)
Code names: MAC-321

Resolves to

Compound

UNIIJ41Q4S20GSCAS352425-37-7PubChem6918589

Structure

InChIKeyXIVMHSNIQAICTR-UQYHODNASA-NSMILES

CCC(=O)O[C@H]1C[C@H]2OC[C@@]2(OC(C)=O)[C@H]2[C@H](OC(=O)C3=CC=CC=C3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C4=CC=CO4)C(C)=C([C@@H](O)C(=O)[C@]12C)C3(C)C

Targets

Q9H4B7TUBB1P07437TUBB

What you can answer from here — as of February 21, 2021

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Milataxel, and which of those have an active Phase 3 trial?

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