Nitrite

DB12529ApprovedWithdrawnSmall molecule

Nitrite is under investigation for the treatment of Heart Failure.

Chemical structure of Nitrite
Mechanism
Curator reviewed
Formula / weight
NO2 · 46.0055 g/mol (avg)
Also known as
Nitrite anion · Nitrite ion

Resolves to

Compound
UNIIJ39976L608CAS14797-65-0ChEBI16301PubChem946
Clinical / RWD
RxNorm1546424
Structure
InChIKeyIOVCWXUNBOPUCH-UHFFFAOYSA-MSMILES[O-]N=O
Targets
P29474NOS3P47989XDHP02144MBQ8WWM9CYGBQ9NPG2NGB

What you can answer from here — as of July 07, 2026

7Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
12Clinical trialsPhase, status and sponsor resolved per trial
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8+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Nitrite, and which of those have an active Phase 3 trial?

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