This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Tenonitrozole
- DrugBank Accession Number
- DB13659
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Tenonitrozole (DB13659)
- Weight
- Average: 255.27
Monoisotopic: 254.977233381 - Chemical Formula
- C8H5N3O3S2
- Synonyms
- Tenonitrozole
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- ATC Codes
- P01AX08 — Tenonitrozole
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as nitrothiazoles. These are compounds containing a thiazole ring which bears a nitro group.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Azoles
- Sub Class
- Thiazoles
- Direct Parent
- Nitrothiazoles
- Alternative Parents
- Thiophene carboxamides / Nitroaromatic compounds / 2-heteroaryl carboxamides / 2,5-disubstituted thiazoles / Heteroaromatic compounds / Secondary carboxylic acid amides / Propargyl-type 1,3-dipolar organic compounds / Organic oxoazanium compounds / Azacyclic compounds / Organopnictogen compounds show 5 more
- Substituents
- 2,5-disubstituted 1,3-thiazole / 2-heteroaryl carboxamide / Allyl-type 1,3-dipolar organic compound / Aromatic heteromonocyclic compound / Azacycle / C-nitro compound / Carboxamide group / Carboxylic acid derivative / Heteroaromatic compound / Hydrocarbon derivative show 17 more
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- PBQ7WLE1WP
- CAS number
- 3810-35-3
- InChI Key
- ZLOXYEZYWCTXHU-UHFFFAOYSA-N
- InChI
- InChI=1S/C8H5N3O3S2/c12-7(5-2-1-3-15-5)10-8-9-4-6(16-8)11(13)14/h1-4H,(H,9,10,12)
- IUPAC Name
- N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide
- SMILES
- O=C(NC1=NC=C(S1)N(=O)=O)C1=CC=CS1
References
- General References
- Not Available
- External Links
- ChemSpider
- 18505
- 236186
- ChEBI
- 135042
- ChEMBL
- CHEMBL1082354
- ZINC
- ZINC000004217523
- Wikipedia
- Tenonitrozole
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.21 mg/mL ALOGPS logP 2.13 ALOGPS logP 2.43 Chemaxon logS -3.1 ALOGPS pKa (Strongest Acidic) 10.08 Chemaxon pKa (Strongest Basic) -4.2 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 87.81 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 59.65 m3·mol-1 Chemaxon Polarizability 22.93 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 159.1219295 predictedDarkChem Lite v0.1.0 [M-H]- 150.87428 predictedDeepCCS 1.0 (2019) [M+H]+ 159.4014295 predictedDarkChem Lite v0.1.0 [M+H]+ 153.26984 predictedDeepCCS 1.0 (2019) [M+Na]+ 159.2434295 predictedDarkChem Lite v0.1.0 [M+Na]+ 159.34883 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:46 / Updated at February 21, 2021 18:54