- Accession Number
Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)
Drug Drug Description Nicotine A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. Caffeine A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. Reserpine For the treatment of hypertension Trospium An antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). Benzatropine An anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia. Methysergide An ergot alkaloid used for the prophylaxis of migraine and cluster headaches. Cabergoline A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes. Theophylline A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. Morphine An opioid agonist used for the relief of moderate to severe acute and chronic pain. Vindesine A vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL). Codeine An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Dihydroergotamine An ergot alkaloid used in the acute treatment of migraine headache and cluster headache. Hydromorphone An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Ipratropium An anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD). Methylergometrine An ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery. Vinorelbine A vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC. Metocurine iodide For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy. Miglustat A glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement. Hyoscyamine For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease... Quinine An alkaloid used to treat uncomplicated Plasmodium falciparum malaria. Miglitol An oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates. Oxycodone An opioid used in the management of moderate to severe pain. Levallorphan For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids. Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough. Anisotropine methylbromide For use in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcer, to reduce further gastric acid secretion and delay gastric emptying. Vincristine A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. Cisatracurium A skeletal muscle relaxant used to facilitate tracheal intubation, muscle relaxation in surgery, or mechanical ventilation. Vinblastine A vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. Atropine A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. Lisuride For the management of Parkinson's Disease Butorphanol An opioid agonist-antagonist used to treat moderate to severe pain. Dyphylline A theophylline derivative used to treat asthma, bronchospasm, and COPD. Pentazocine An analgesic used to treat moderate to severe pain. Galantamine A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. Ergotamine A alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. Nicergoline For the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration. Naltrexone A narcotic antagonist used in opioid overdose. Apomorphine A morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease. Homatropine methylbromide A muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. Atracurium besylate A non-depolarizing neuromuscular blocker used to facilitate endotracheal intubation and relax skeletal muscles during surgery. Scopolamine An anticholinergic used to treat excessive salivation, colicky abdominal pain, bradycardia, diverticulitis, IBS, and motion sickness. Irinotecan An antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum. Cryptenamine For the treatment of hypertension. Pentoxifylline A methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs. Enprofylline Used in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Nalbuphine An opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery. Levorphanol An opioid analgesic used to treat moderate to severe pain. Cocaine An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Buprenorphine A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction. Hydrocodone An opioid agonist used as an analgesic and antitussive agent. Physostigmine A cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity. Dimenhydrinate A medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness. Topotecan An antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer. Ergoloid mesylate A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. Pilocarpine A muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy. Deserpidine An alkaloid that has been used to manage hypertension. Papaverine An alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms". Rescinnamine For the treatment of hypertension. Naloxone An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. Pergolide A long-acting dopamine agonist that is uncommonly used for the management of Parkinson's disease, due to the risk for cardiac valvulopathy. Oxymorphone An opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies. Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to... Bromocriptine A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Ergometrine An ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony. Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema. Metocurine Metocurine is a muscle relaxant. Yohimbine An alpha-2-adrenergic blocker and sympatholytic found in supplements used to. Colchicine An alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF). Tiotropium A long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Theobromine theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension. Ajmaline For use as an antiarrhythmic agent. 5-Methoxy-N,N-diisopropyltryptamine 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a... Dihydroetorphine Not Available Diamorphine An opioid analgesic agent used in the relief of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnea in acute pulmonary edema. Ethylmorphine Ethylmorphine is an analgesic used for pain relief. Cyprenorphine Not Available Fenethylline Not Available Etorphine Etorphine is only available for its use in veterinary. This main usage is related to the immobilization of large mammals. Benzoylecgonine Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after... Ecgonine Not Available Desomorphine Not Available Drotebanol Not Available Diprenorphine Diprenorphine is indicated to reverse the effects of powerful opioids including etorphine and carfentanil, often used for tranquilizing large animals. This drug is not approved for use in humans. Dihydrocodeine An opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Dihydromorphine Dihydromorphine is an opioid analgesic used for moderate to severe pain relief. Tropinone Not Available 8-azaxanthine Not Available 7-Hydroxystaurosporine Not Available Staurosporine An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20) Xanthine A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being... K-252a Not Available Duvoglustat An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity. Pseudotropine Not Available Berberine An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal... Arecoline An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the... Methylecgonine Not Available Camptothecin Investigated for the treatment of cancer. Lysergic acid diethylamide Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by... Omacetaxine mepesuccinate A cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors. Voacamine For the treatment of malaria. Also under investigation for the modulation of multidrug resistance in cancer cells. Phenserine For the treatment of Alzheimer's disease (AD). Altropane Investigated for use/treatment in attention deficit/hyperactivity disorder (ADHD), parkinson's disease, and pediatric indications. Migalastat An alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant. Lobeline Investigated for use/treatment in addictions. Vintafolide Investigated for use/treatment in solid tumors. NS-2359 Investigated for use/treatment in addictions, attention deficit/hyperactivity disorder (ADHD), and depression. Cositecan Investigated for use/treatment in brain cancer, lung cancer, and melanoma. Rivanicline Investigated for use/treatment in ulcerative colitis. IT-101 Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors. XMT-1001 Investigated for use/treatment in solid tumors. Rubitecan Investigated for use/treatment in pancreatic cancer, leukemia (unspecified), melanoma, ovarian cancer, and cancer/tumors (unspecified). Noscapine Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma. Nalmefene An opioid antagonist used in conjunction with psychosocial support to help adults with alcohol dependence reduce alcohol consumption. Naxifylline Investigated for use/treatment in congestive heart failure. Propentofylline Investigated for use/treatment in alzheimer's disease. Midostaurin An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). Gimatecan Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative. Sparteine Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker so it falls under the category... Drotaverine Used in the treatment of functional bowel disorders and alleviating pain in renal colic. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Methylnaltrexone A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. 3-isobutyl-1-methyl-7H-xanthine Not Available Ioflupane I-123 A radiopharmaceutical used in single photon emission computed tomography (SPECT) brain imaging to help diagnose patients with suspected Parkinsonian syndromes. Uric acid At present (August 2013), there is no approved indication for uric acid. The potential therapeutic use for uric acid is as an adjunct in acute ischemic stroke. Aclidinium An inhaled long-acting anticholinergic used as a maintenance bronchodilator in patients with chronic obstructive pulmonary disease (COPD). Fentonium Fentonium is an atropine derivative. Naloxegol A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. Xanthinol A vasodilatory niacin found in diet supplements. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. Pholcodine Pholcodine is indicated as a cough suppressant for the temporary relief of non-productive dry cough. It is stated to present a required label indication of "temporary relief of dry cough."... Cimetropium Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which... Doxofylline Indicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component. Butylscopolamine An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain. Homatropine An anticholinergic agent used to dilate the pupil, treat inflammation of the uveal tract, and suppress a cough. Dihydroergocornine A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. Epicriptine Methscopolamine Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The... Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Nalorphine Used to reverse opioid overdose. Metoserpate Not Annotated Bicuculline Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and... Thiocolchicoside Thiocolchicoside is a skeletal muscle-relaxant drug used in the treatment of orthopedic, traumatic and rheumatologic disorders . It is indicated as an adjuvant drug in the treatment of painful muscle... Vinflunine A vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed. Psilocybin Psilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA. Anisodamine Anisodamine has been investigated for the treatment of Intestinal Diseases. Axelopran Axelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation. Oxitropium Oxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive. Tetrahydropalmatine Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity). Namitecan Namitecan has been used in trials studying the treatment of Solid Tumors. Vinpocetine Vinpocetine has been investigated for the treatment of Epilepsy. Exatecan Exatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others. Lurtotecan Lurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer). Moxaverine Moxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow. AR-67 AR-67 has been used in trials studying the treatment of GBM, Tumors, Gliosarcoma, Solid Malignancies, and Glioblastoma Multiforme, among others. 10-hydroxycamptothecin 10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)). Lisofylline Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus. Zalypsis Zalypsis has been used in trials studying the treatment of Lymphoma, Solid Tumors, Ewing's Sarcoma, Endometrial Cancer, and Uterine Cervical Cancer, among others. Belotecan Belotecan has been investigated for the treatment of Epithelial Ovarian Cancer. 9-aminocamptothecin Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others. Samidorphan Samidorphan has been used in trials studying the treatment of Schizophrenia, Alcohol Dependence, and Binge Eating Disorder. Tonapofylline Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure. Patidegib Patidegib has been investigated for the treatment of Conventional Chondrosarcoma. Rolofylline Rolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure. Solamargine Solamargine has been used in trials studying the treatment of Actinic Keratosis. Pegamotecan Pegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer. Reproterol Reproterol has been used in trials studying the treatment of Asthma, Exercise-Induced. Sacituzumab govitecan Sacituzumab govitecan targets TROP-2-expressing cancer cells through a humanized antibody (RS7) before subsequently becoming internalized and releasing the topoisomerase I inhibitor SN-38 to induce DNA damage-mediated apoptosis.[L13002] Cafedrine Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Theodrenaline Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). 8-cyclopentyl-1,3-dipropylxanthine CPX has been used in trials studying the treatment of Cystic Fibrosis. CT-2584 CT-2584 has been used in trials studying the treatment of Prostate Cancer. Ambroxol acefyllinate Not Annotated Bamifylline Bamifylline is a selective A1 adenosine receptor antagonist. Atracurium Not Annotated Demecolcine Not Annotated Dihydroergocristine An ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's. Vincamine Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow. Dihydroergocryptine Not Annotated Emetine Not Annotated Terguride Not Annotated Proxyphylline Not Annotated Nicomorphine Not Annotated Etybenzatropine Not Annotated Nalfurafine Not Annotated Metergoline Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration... Prajmaline Not Annotated Acefylline Not Annotated Bietaserpine Not Annotated Etamiphylline Not Annotated Phenazocine Not Annotated Pentifylline Not Annotated Alcuronium A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant. Lorajmine Not Annotated Tretoquinol Not Annotated Hydroquinine Not Annotated Vinburnine Not Annotated Dimemorfan Not Annotated Bufylline Not Annotated Methylatropine Not Annotated Dehydroemetine Not Annotated Harmaline Not Annotated Bromotheophylline Bromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with... Furafylline Furafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline. Tetrandrine Not Annotated 8-chlorotheophylline When used in combination with DB01075 as the antiemetic DB00985, 8-chlorotheophylline is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness. Dextrorphan Not Annotated 7-ethyl-10-hydroxycamptothecin Investigated for use/treatment in colorectal cancer. Rauwolfia serpentina root Rauwolfia alkaloids are indicated in the treatment of hypertension . Rauwolfia alkaloids have been used for relief of symptoms in agitated psychotic states such as schizophrenia; however, use as antipsychotics... Almitrine For the treatment of chronic obstructive pulmonary disease. Morphine glucuronide Investigated for use/treatment in pain (acute or chronic). Firtecan pegol Firtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer). 18-methoxycoronaridine 18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients). Hydroquinidine Hydroquinidine is under investigation in clinical trial NCT00927732 (Hydroquinidine Versus Placebo in Patients With Brugada Syndrome). Posiphen Posiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease). Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate). Naldemedine An opioid antagonist used to to treat opioid-induced constipation. Deptropine Not Annotated Tenidap Not Annotated Loxicodegol Loxicodegol was developed as an opioid analgesic with low abuse potential for use in treating chronic pain . An application has been filed for FDA approval of Loxicodegol for use... Lucerastat Lucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease). PCS-499 PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients). Colchiceine Colchiceine is one of several metabolites of the anti-gout medication colchicine. Variolin B Not Available Deacetoxyvinzolidine Not Available Harmine Not Available Raubasine Not Annotated Strychnine Not Annotated Butropium Not Annotated Diflomotecan Diflomotecan is under investigation in clinical trial NCT00080015 (Diflomotecan (BN80915) Administered Once Every 3 Weeks in Treating Patients With Sensitive Small Cell Lung Cancer (SCLC)). Nazartinib Nazartinib is under investigation in clinical trial NCT03529084 (Phase III Study of Nazartinib (EGF816) Versus Erlotinib/gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating Mutations).
- Drugs & Drug Targets