Pyridines
- Name
- Pyridines
- Accession Number
- DBCAT000227
- Description
Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
- Drugs
Drug Drug Description Pyridoxal phosphate A vitamin available in many formulations to correct vitamin B6 deficiency. Pyridoxine A vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy. Nicotine A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. Pantoprazole A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. Indinavir A protease inhibitor used to treat HIV infection. Milrinone A PDE-III inhibitor with inotropic, lusitropic, and vasodilatory properties used for the short-term treatment of acute decompensated heart failure. Nevirapine A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. Disopyramide A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. Omeprazole A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. Doxylamine An antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy. Amlodipine A calcium channel blocker used to treat hypertension and angina. Eszopiclone A sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. Dexbrompheniramine An antihistamine used to treat allergy symptoms including upper respiratory tract symptoms. Triprolidine A sedating antihistamine combined with pseudoephedrine and guaifenesin in various types of cold and allergy medications to relieve allergy symptoms, hay fever and common cold symptoms, and to aid in sleep. Lansoprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Pyridostigmine A cholinesterase inhibitor used for symptomatic treatment of myasthenia gravis and congenital myasthenic syndromes and to reverse neuromuscular blockade by nondepolarizing muscle relaxants. Niacin A B vitamin used to treat hypertriglyceridemia and pellagra. Trazodone A serotonin uptake inhibitor used to treat major depressive disorder. Clopidogrel An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. Tripelennamine A histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold. Tropicamide A muscarinic receptor antagonist used to induce mydriasis and cycloplegia for diagnostic procedures. Tadalafil A phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. Brompheniramine A histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold. Metyrapone A steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function. Atazanavir An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. Chlorpheniramine A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. Nifedipine A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. Phenazopyridine A local anesthetic used for the symptomatic relief of pain, burning, urgency, frequency, and general discomfort caused by lower urinary tract irritations that are a result of infection, trauma, surgery, endoscopic procedures, or the passage of equipment or catheters. Pheniramine An antihistamine used to treat allergic rhinitis and pruritus. Tolperisone A muscle relaxant used to relieve spasticity after stroke in adults. Apixaban An anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery. Mepyramine An antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. Dabigatran etexilate An anticoagulant used for the prevention of venous thromboembolic events or stroke in patients with recent elective hip or knee replacement surgery and atrial fibrillation. Betahistine An antivertigo agent used for the reduction of episodes of vertigo association with Ménière's disease. Dimetindene A 1st generation selective H1 antagonist used topically as an antipruritic and orally to treat allergies. Levamlodipine A calcium channel blocker used to treat hypertension. Acrivastine An antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion. Dexchlorpheniramine maleate A first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema. Flunixin Flunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form.... Cabotegravir An HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV-1 infection. Abemaciclib A medication used to treat HR+ HER2- advanced or metastatic breast cancer. Doravirine A non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections. Lurbinectedin A chemotherapeutic DNA alkylating agent used in the treatment of metastatic small-cell lung cancer. Tazemetostat A methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection. Pyritinol A vitamin B6 analog indicated as an adjunct therapy in the treatment of a wide variety of disorders of the brain. Methyl nicotinate A methyl ester of niacin used to treat muscle and joint pain. Nicotinyl alcohol A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. [PubChem] Torasemide A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease. Zolpidem A sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency. Risedronic acid A bisphosphonate used to treat osteoporosis and Paget's disease. Etoricoxib A selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis. Asciminib An inhibitor of ABL/BCR-ABL1 tyrosine kinase for the treatment of patients with Philadelphia chromosome-positive CML, including those with the T315I mutation. Flortaucipir F-18 A small lipophilic tracer containing [18F]fluoride capable of crossing the blood-brain barrier and binding to aggregated tau protein; used in PET imaging for the diagnosis of Alzheimer's disease. Abametapir A pediculicide metalloproteinase used topically in the treatment of head lice infection. Fostamatinib A spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment. Amlexanox Used as a paste in the mouth to treat aphthous ulcers (canker sores). Amrinone A positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure. Roflumilast A selective phosphodiesterase-4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) and to treat plaque psoriasis. 3-Methylpyridine Not Available 4-O-Demethylpenclomedine Investigated for use/treatment in solid tumors. Tucidinostat Investigated for use/treatment in cancer/tumors (unspecified). Flupirtine Investigated for use/treatment in fibromyalgia. Picosulfuric acid A stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults. Lumacaftor A protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene. Amprolium Amprolium is a coccidiostat used in poultry. Buparlisib Buparlisib has been used in trials studying the treatment and basic science of Lymphoma, Metastases, Lung Cancer, Solid Tumors, and Breast Cancer, among others. Ilorasertib Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others. Ribociclib A kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer. Flumatinib Flumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic. Golvatinib Golvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck. BMS-777607 BMS-777607 has been investigated for the basic science of Malignant Solid Tumour. Lorlatinib An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. Pyroxamide Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others. Pradigastat Pradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD). Ozenoxacin A quinolone antibiotic used to treat impetigo caused by susceptible bacteria. Pexidartinib An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. Penclomedine Penclomedine has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific. Enasidenib An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. Ulixertinib Ulixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity . It is currently in clinical trials for the treatment of a wide range of... Dabigatran Dabigatran is the active form of the orally bioavailable prodrug dabigatran etexilate. Miransertib Miransertib is under investigation in clinical trial NCT01473095 (Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma). VS-4718 VS-4718 is under investigation in clinical trial NCT02215629 (Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia). Danicopan Danicopan is under investigation in clinical trial NCT03459443 (A Proof of Concept Study for a 12 Month Treatment in Patients With C3 Glomerulopathy (C3G) or Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN)). V116517 V116517 is under investigation in clinical trial NCT01688947 (Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)). GSK2256098 GSK2256098 is under investigation in clinical trial NCT02523014 (Vismodegib and FAK Inhibitor GSK2256098 in Treating Patients With Progressive Meningiomas). Capadenoson Capadenoson is under investigation in clinical trial NCT00518921 (Capadenoson in Angina Pectoris). NSI-189 NSI-189 is under investigation in clinical trial NCT02695472 (Study of NSI-189 for Major Depressive Disorder). Pyridoxal Pyridoxal is one of the natural forms available of vitamin B6, therefore, it is used for nutritional supplementation and for treating dietary shortage or imbalances. Ticlopidine A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). Isradipine A dihydropyridine calcium channel blocker used for the treatment of hypertension. Nimodipine A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. Sorafenib A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma. Nisoldipine A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension. Lercanidipine A calcium channel blocker for the management of hypertension. Ethionamide A second line antitubercular agent used to treat tuberculosis when other treatments have failed. Nicardipine A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. Esomeprazole A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion. Tazarotene An acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis. Isoniazid An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. Alosetron A 5-HT3 antagonist used to treat diarrhea-predominant IBS. Felodipine A calcium channel blocker used to treat hypertension. Nitrendipine A dihydropyridine calcium channel blocker indicated in the treatment of arterial hypertension. Mimosine Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca. Rabeprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Ciclopirox A broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients. Quinolinic Acid A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.... LG-100268 LG-100268 is a retinoid X receptor (RXR) selective compound. Pyridoxine phosphate Not Available PD173955 Not Available Nicotinamide An ingredient found in a variety of cosmetic products. Dipicolinic acid Not Available Arecoline An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the... Niflumic acid A cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma. Atpenin A5 Not Available 2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one Not Available Iproniazid For the treatment of depression (originally intended to treat tuberculosis). Methapyrilene Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. Nialamide Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine. Zimelidine For the treatment of depression. Pirfenidone An agent used for the treatment of idiopathic pulmonary fibrosis (IPF). Dexlansoprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Motesanib Investigated for use/treatment in solid tumors. Rivanicline Investigated for use/treatment in ulcerative colitis. AZD-8330 Investigated for use/treatment in cancer/tumors (unspecified). Hydronidone Investigated for use/treatment in liver disease. Nicaraven Investigated for use/treatment in cerebrovascular disease (unspecified). R-1487 Investigated for use/treatment in rheumatoid arthritis. Dalfampridine A potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS). Nilvadipine A calcium channel blocker used to manage arterial hypertension. Mangafodipir An organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas. PH-797804 PH-797804 has been investigated for the treatment of Osteoarthritis. Deferiprone An iron chelator used to treat patients with transfusional iron overload caused by thalassemia syndromes. N-methylnicotinamide N-methylnicotinamide is an experimental drug with no approved indication. Guvacine There is no approved indication for guvacine. Crizotinib A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive. Perampanel A non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy. Trametinib A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. Inositol nicotinate A vasodilator and source of niacin found in dietary supplements. Xanthinol A vasodilatory niacin found in diet supplements. Phenaridine Phenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. It was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl. In rat studies,... Etoperidone Etoperidone has been studied for the treatment of depression , tremors in Parkinson, extrapyramidal symptoms and male impotence . It is not certain if it was ever approved and marketed... Clonixin An NSAID used to relieve pain associated with arthritis, migraines, and various soft tissue disorders. Nicorandil A vasodilatory drug that functions through potassium channels and intracellular cGMP concentrations commonly used to treat angina. Barnidipine A calcium channel blocker used to treat various forms of hypertension. Aranidipine Aranidipine has been used for many years to treat angina pectoris and hypertension. Azelnidipine For the treatment of hypertension. Benidipine A synthetic dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. Cilnidipine A dihydropyridine calcium channel blocker with action on both N- and L-type calcium channels used to treat hypertension. Darodipine Darodipine is a calcium channel blocker. Efonidipine For the treatment of hypertension. Lacidipine A lipophilic dihydropyridine calcium channel blocker with a slow onset of action used to treat hypertension. Manidipine A dihydropyridine calcium channel blocker used to treat hypertension. Niguldipine Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties. Niludipine Niludipine is a calcium channel blocker. Morniflumate An NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems. Metralindole Investigated for the treatment of depression. Propyliodone Radiopaque medium usually in oil; used in bronchography. Lapyrium Used as a surfactant, antistatic agent, and biocide in cosmetic products . Cetylpyridinium A compound used to reduce plaque and gingivitis, as well as whiten teeth. Zinc picolinate Zinc picolinate is a zinc salt of picolinic acid. It is available as OTC dietary supplements as a source of zinc to treat and prevent zinc deficiency. The absorption of... Chromium picolinate Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. Chromium picolinate is used as a nutritional supplement for... Efrotomycin Not Annotated Amifampridine A voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome. Pyridoxamine Pyridoxamine has been used in trials studying the treatment of Kidney Stones. Peficitinib Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others. Trigonellamide Trigonellamide is under investigation in clinical trial NCT01930240 (The Safety of a Hypolipidemic Agent in Healthy Normal Volunteers). PF-04991532 PF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders. BMS-903452 BMS-903452 has been used in trials studying the treatment of Diabetes. Bictegravir An integrase inhibitor used to treat HIV infections. Alvelestat Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease. Ilaprazole Ilaprazole has been investigated in Helicobacter Infections. PF-04691502 PF-04691502 has been used in trials studying the treatment of Cancer, Breast Neoplasms, Early Breast Cancer (Phase 2), and Advanced Breast Cancer (Phase 1b). GDC-0623 GDC-0623 has been used in trials studying the treatment of Solid Cancers. Dinaciclib Dinaciclib has been used in trials studying the treatment of rrMM, rrCLL, rrDLBCL, Solid Tumors, and Solid Neoplasm, among others. JNJ-40411813 JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia, Perceptual Disorders, and Major Depressive Disorder. Dilmapimod Dilmapimod has been used in trials studying the treatment and diagnostic of Nerve Trauma, Inflammation, Pain, Neuropathic, Arthritis, Rheumatoid, and Coronary Heart Disease, among others. Itacitinib Itacitinib has been used in trials studying the treatment of Melanoma, Carcinoma, Metastatic Cancer, Endometrial Cancer, and B-cell Malignancies, among others. TAK-733 TAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and Advanced Non-hematologic Malignancies. Vadadustat An oral hypoxia-inducible factor prolyl-hydroxylase inhibitor being investigated in the treatment of anemia secondary to chronic kidney disease. Merestinib Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others. LY-2886721 LY2886721 has been used in trials studying the basic science of Alzheimer's Disease. Ondelopran Ondelopran has been used in trials studying the treatment of Alcohol Dependence. Protionamide An antitubercular thioamide-derivative used in the treatment of multi-drug resistant (MDR) tuberculosis and leprosy. TAK-901 TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others. Boscalid Boscalid has been investigated for the treatment of OSDI, Glaucoma, Staining, Schirmers, and Disease Severity, among others. Nicoboxil A medication used to treat acute back pain. Tinoridine Tinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults). AGN-201904 Agn 201904 has been used in trials studying the prevention of Peptic Ulcer. Pyrithyldione Not Annotated Nifenazone Not Annotated Nicofuranose Not Annotated Niceritrol Not Annotated Nicomorphine Not Annotated Diodone Not Annotated Nikethamide A nicotinic acid derivative indicated as a respiratory stimulant. Dexchlorpheniramine A chlorpheniramine enantiomer antihistamine indicated in the treatment of sunburns, insect bites, and allergic reactions of the skin. Niaprazine Niaprazine is a selective brain catecholamine depletor. Distigmine A cholinesterase inhibitor indicated in the treatment of neurogenic bladder dysfunction or myasthenia gravis. Ciclonicate Not Annotated Bemegride Bemegride is a CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose. Piromidic acid Not Annotated Fazadinium bromide Not Annotated Obidoxime Not Annotated Dexrabeprazole A proton pump inhibitor indicated in the treatment of gastroesophageal reflux disease and gastrointestinal ulcers. Mebhydrolin An antihistamine indicated in the treatment of allergies. Pipemidic acid A quinolone antibiotic indicated in the treatment of susceptible urinary tract infections. Baloxavir marboxil A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza. Dexniguldipine Not Annotated Fenebrutinib Fenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin). AZD-4017 AZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure). Pimasertib Pimasertib is under investigation in clinical trial NCT01378377 (Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus). Nicotinamide riboside Nicotinamide riboside is under investigation in clinical trial NCT03432871 (Nicotinamide Riboside and Mitochondrial Biogenesis). Flortaucipir Flortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol). Cilofexor Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis). Ravoxertinib Ravoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors). Modimelanotide Modimelanotide is under investigation in clinical trial NCT01897519 (A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High... AMG-337 AMG-337 is under investigation in clinical trial NCT03147976 (QUILT-3.036: AMG 337 in Subjects With Advanced or Metastatic Solid Tumors). Baloxavir Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)). Benzyl nicotinate A rubefacient and vasodilator used in combination with analgesics in topical preparations. MK-0668 Not Annotated Tocopheryl nicotinate A vitamin E supplement indicated in the treatment of high cholesterol and narrowing of peripheral arteries. Piroctone Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. Recently... Modipafant Modipafant is under investigation in clinical trial NCT02569827 (Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore). Nazartinib Nazartinib is under investigation in clinical trial NCT03529084 (Phase III Study of Nazartinib (EGF816) Versus Erlotinib/gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating Mutations). S-777469 S-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis). Metadoxine A medication used to increase the clearance of alcohol in patients with chronic alcohol dependancy. BLZ-945 Not Annotated Picolinic acid Investigated for use/treatment in acne, herpes labialis infections (cold sores), and venereal disease. Olprinone Not Annotated Setanaxib Not Annotated Isonicotinic acid Not Annotated ZK-93423 ZK-93423 is a beta-carboline with muscle relaxant activity with agonistic properties at the benzodiazepine receptor. Omidenepag isopropyl An agonist of the prostaglandin EP2 receptor indicated for the reduction of elevated intraocular pressure. Farudodstat Farudodstat (ASLAN003) is under investigation in clinical trial NCT03451084 (A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia). Lansoprazole sulfone Not Annotated Altiratinib Not Annotated - Drugs & Drug Targets