NAV

Talditercept alfa

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Talditercept alfa
DrugBank Accession Number
DB16337
Background

Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).

Type
Biotech
Groups
Investigational
Synonyms
  • Adnectin, anti-(human growth differentiation factor 8) (synthetic clone prd-1474 fibronectin type iii tenth domain (10fn3)-based isoform
  • Bivalent Anti-Human Myostatin Adnectin-Igg1
  • Bms-986089 (fully human anti-myostatin adnectin)
  • Immunoglobulin g1 (human fc fragment) fusion protein with peptide (synthetic 17-amino acid linker) fusion protein with adnectin, anti-(human growth differentiation factor 8) (human clone bms-986089 fibronectin tenth type iii domain-derived), dimer
  • Taldefgrobep alfa
  • Talditercept alfa
External IDs
  • BMS-986089
  • RO-7239361
  • RO7239361
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
766C38JSAR
CAS number
1580555-26-5

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Active Not RecruitingTreatmentNeuromuscular Disorders / Spinal Muscular Atrophy (SMA)1
2, 3CompletedTreatmentDuchenne Muscular Dystrophy (DMD)1
1CompletedOtherHealthy Adults1
1CompletedOtherHealthy Volunteers (HV)1
1, 2TerminatedBasic ScienceDuchenne Muscular Dystrophy (DMD)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at December 15, 2020 20:02 / Updated at December 01, 2022 11:30