Dimethylaminomicheliolide

DB17111InvestigationalSmall molecule

Dimethylaminomicheliolide: Overview.

Mechanism: Pharmacologically active on Inhibitor of nuclear factor kappa-B kinase subunit beta, Signal transducer and activator of transcription 3, and Nuclear factor NF-kappa-B
Curator reviewed
Formula / weight: C₁₇H₂₇NO₃ · 293.407 g/mol (avg)
Also known as: 11.BETA.,13-DIHYDRO-13-(DIMETHYLAMINO)MICHELIOLIDE · AZULENO(4,5-B)FURAN-2(3H)-ONE, 3-((DIMETHYLAMINO)METHYL)-3A,4,5,7,8,9,9A,9B-OCTAHYDRO-9-HYDROXY-6,9-DIMETHYL-, (3R,3AS,9R,9AS,9BS)-
Code names: ACT-001

Resolves to

Compound

Structure

InChIKeyZPBIJIIQXPRJSS-WNZSCWOMSA-NSMILES[H][C@@]12CCC(C)=C3CC[C@@](C)(O)[C@]3([H])[C@@]1([H])OC(=O)[C@H]2CN(C)C

Targets

What you can answer from here — as of August 29, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Dimethylaminomicheliolide, and which of those have an active Phase 3 trial?

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