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Technetium TC-99M trofolastat

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Data Packages
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Overview

Structure
DrugBank ID
DB18803
Type
Small Molecule
US Approved
NO
Other Approved
NO
Patents
0
Indicated Conditions
0
Clinical Trials
Phase 0
0
Phase 1
3
Phase 2
1
Phase 3
1
Phase 4
0

Identification

Generic Name
Technetium TC-99M trofolastat
DrugBank Accession Number
DB18803
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
Similar Structures
Weight
Average: 1134.769
Monoisotopic: 1134.187258788
Chemical Formula
C40H47N10O23Tc
Synonyms
  • (oc-6-33)-tricarbonyl(n2-(((1s)-1,3-dicarboxypropyl)carbamoyl)-l-.gamma.-glutamyl-n6,n6-bis((1-(2-(bis(carboxymethyl)amino)-2-oxoethyl)-1h-imidazol-2-yl-.kappa.n3)methyl)-l-lysine-.kappa.n6)(99mtc)technetium(+)
  • 99mTc-MIP-1404
  • Technetium tc-99m trofolastat cation
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available
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Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
W23EFJ3KDD
CAS number
1333204-77-5
InChI Key
RQPDXUDTXCPYGU-OIOJJZKLSA-K
InChI
InChI=1S/C37H50N10O20.3CO.Tc/c48-26(6-4-22(35(63)64)41-37(67)42-23(36(65)66)5-7-29(51)52)40-21(34(61)62)3-1-2-10-43(13-24-38-8-11-44(24)15-27(49)46(17-30(53)54)18-31(55)56)14-25-39-9-12-45(25)16-28(50)47(19-32(57)58)20-33(59)60;3*1-2;/h8-9,11-12,21-23H,1-7,10,13-20H2,(H,40,48)(H,51,52)(H,53,54)(H,55,56)(H,57,58)(H,59,60)(H,61,62)(H,63,64)(H,65,66)(H2,41,42,67);;;;/q;;;;+4/p-3/t21-,22-,23-;;;;/m0..../s1/i;;;;1+1
IUPAC Name
SMILES
[H+].[H+].[H+].[H+].[H+].[99Tc+4].[C-]#[O+].[C-]#[O+].[C-]#[O+].[O-]C(=O)CC[C@H](NC(=O)N[C@@H](CCC(=O)N[C@@H](CCCCN(CC1=NC=CN1CC(=O)N(CC([O-])=O)CC([O-])=O)CC1=NC=CN1CC(=O)N(CC([O-])=O)CC([O-])=O)C([O-])=O)C([O-])=O)C([O-])=O

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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3CompletedDiagnosticProstate Cancer1somestatusstop reasonjust information to hide
2CompletedDiagnosticProstate Cancer1somestatusstop reasonjust information to hide
1CompletedDiagnosticProstate Cancer3somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 21, 2024 19:33 / Updated at November 05, 2024 05:15