Type 2 Diabetes Mellitus

Also known as: Non-Insulin-Dependent Diabetes Mellitus / Type 2 Diabetes Mellitus (T2DM) / Type 2 Diabetes / Diabetes, Type II / Type II Diabetes Mellitus / T2DM / Type Two Diabetes Mellitus / Diabetes mellitus non-insulin-dependent / NIDDM / Diabetes mellitus: [adult onset] or [noninsulin dependent] / Diabetes mellitus type 2 (disorder) / Diabetes mellitus: [adult onset, with no mention of complication] or [maturity onset] or [non-insulin dependent] / Diabetes Mellitus, Type 2 / Diabetes mellitus non insulin-dep / Maturity onset diabetes / Diabetes mellitus maturity onset

DrugDrug NameDrug Description
DB00284AcarboseAn alpha-glucosidase inhibitor used in adjunctly with diet and exercise for the management of glycemic control in patients with type 2 diabetes mellitus.
DB09043AlbiglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
DB06203AlogliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus.
DB01076AtorvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DB01200BromocriptineA dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome.
DB08907CanagliflozinA sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM.
DB00672ChlorpropamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
DB00930ColesevelamA bile acid sequestrant used to lower LDL-C in adults with hyperlipidemia and pediatric patients with heterozygous familial hypercholesterolemia, and to improve glycemic control in type 2 diabetes.
DB06292DapagliflozinA sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus.
DB09045DulaglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
DB09038EmpagliflozinAn SGLT2 inhibitor used to manage type 2 diabetes mellitus.
DB11827ErtugliflozinA SGLT2 inhibitor used to treat type 2 diabetes mellitus.
DB01276ExenatideA GLP-1 agonist used in the management of type 2 diabetes mellitus.
DB12412GemigliptinGemigliptin is under investigation in Type 2 Diabetes Mellitus. Gemigliptin has been investigated for the treatment of Cancer and Cisplatin Adverse Reaction.
DB01120GliclazideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
DB00222GlimepirideA sulfonylurea drug used to treat type 2 diabetes mellitus.
DB01067GlipizideA sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release.
DB01251GliquidoneUsed in the treatment of diabetes mellitus type 2.
DB00040GlucagonA form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures.
DB01016GlyburideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
DB09564Insulin degludecA long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus.
DB01307Insulin detemirA long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus.
DB00047Insulin glargineA modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus.
DB00046Insulin lisproA modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus.
DB08882LinagliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.
DB00166Lipoic acidFor nutritional supplementation, also for treating dietary shortage or imbalance.
DB06655LiraglutideA GLP-1 analog used in the management of type 2 diabetes mellitus and prevention of cardiovascular complications associated with diabetes.
DB09265LixisenatideA GLP-1 receptor agonist used for the management of type 2 diabetes mellitus.
DB12214LuseogliflozinLuseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
DB00331MetforminA biguanide drug used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus and used off-label for insulin resistance in polycystic ovary syndrome (PCOS).
DB00491MiglitolAn oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
DB01252MitiglinideFor the treatment of type 2 diabetes.
DB00731NateglinideA meglitinide used to treat non insulin dependent diabetes mellitus.
DB01132PioglitazoneA thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus.
DB01278PramlintideAn amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy.
DB00912RepaglinideA antihyperglycemic used to improve glycemic control in diabetes.
DB00412RosiglitazoneA thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes.
DB06335SaxagliptinAn DPP-4 inhibitor used for the management of type 2 diabetes mellitus.
DB13928SemaglutideA glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus.
DB00641SimvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
DB01261SitagliptinAn oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.
DB11950TeneligliptinTeneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus.
DB00839TolazamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
DB01124TolbutamideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
DB00273TopiramateAn anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines.
DB15323TrelagliptinTrelagliptin is under investigation in clinical trial NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus").
DB04876VildagliptinA once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus.
DB04878VogliboseFor the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.
DrugDrug NameTargetType
DB00284AcarboseMaltase-glucoamylase, intestinaltarget
DB00284AcarboseLysosomal alpha-glucosidasetarget
DB00284AcarboseSucrase-isomaltase, intestinaltarget
DB00284AcarbosePancreatic alpha-amylasetarget
DB09043AlbiglutideGlucagon-like peptide 1 receptortarget
DB06203AlogliptinDipeptidyl peptidase 4target
DB06203AlogliptinCytochrome P450 3A4enzyme
DB06203AlogliptinCytochrome P450 2D6enzyme
DB01076Atorvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01076AtorvastatinCytochrome P450 3A4enzyme
DB01076AtorvastatinDipeptidyl peptidase 4target
DB01076AtorvastatinCytochrome P450 2D6enzyme
DB01076AtorvastatinCytochrome P450 2C9enzyme
DB01076AtorvastatinCytochrome P450 2C19enzyme
DB01076AtorvastatinCytochrome P450 3A5enzyme
DB01076AtorvastatinCytochrome P450 3A7enzyme
DB01076AtorvastatinP-glycoprotein 1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01076AtorvastatinMultidrug resistance-associated protein 4transporter
DB01076AtorvastatinMultidrug resistance-associated protein 5transporter
DB01076AtorvastatinMultidrug resistance-associated protein 1transporter
DB01076AtorvastatinCytochrome P450 2B6enzyme
DB01076AtorvastatinCytochrome P450 2C8enzyme
DB01076AtorvastatinAryl hydrocarbon receptortarget
DB01076AtorvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01076AtorvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01076AtorvastatinCanalicular multispecific organic anion transporter 1transporter
DB01076AtorvastatinBile salt export pumptransporter
DB01076AtorvastatinSerum albumincarrier
DB01076AtorvastatinHistone deacetylase 2target
DB01076AtorvastatinNuclear receptor subfamily 1 group I member 3target
DB01200BromocriptineDopamine D2 receptortarget
DB01200BromocriptineCytochrome P450 3A4enzyme
DB01200Bromocriptine5-hydroxytryptamine receptor 1Dtarget
DB01200BromocriptineAlpha-2A adrenergic receptortarget
DB01200BromocriptineDopamine D3 receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 1Atarget
DB01200BromocriptineAlpha-2C adrenergic receptortarget
DB01200BromocriptineAlpha-2B adrenergic receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Btarget
DB01200BromocriptineDopamine D4 receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Atarget
DB01200Bromocriptine5-hydroxytryptamine receptor 1Btarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Ctarget
DB01200BromocriptineDopamine D5 receptortarget
DB01200BromocriptineDopamine D1 receptortarget
DB01200BromocriptineAlpha-1A adrenergic receptortarget
DB01200BromocriptineAlpha-1B adrenergic receptortarget
DB01200BromocriptineAlpha-1D adrenergic receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 7target
DB01200BromocriptineP-glycoprotein 1transporter
DB08907CanagliflozinUDP-glucuronosyltransferase 1-9enzyme
DB08907CanagliflozinUDP-glucuronosyltransferase 2B4enzyme
DB08907CanagliflozinCytochrome P450 3A4enzyme
DB08907CanagliflozinSodium/glucose cotransporter 2target
DB08907CanagliflozinP-glycoprotein 1transporter
DB08907CanagliflozinCanalicular multispecific organic anion transporter 1transporter
DB08907CanagliflozinAlpha-1-acid glycoprotein 1carrier
DB08907CanagliflozinATP-binding cassette sub-family G member 2transporter
DB00672ChlorpropamideATP-binding cassette sub-family C member 8target
DB00672ChlorpropamideSolute carrier family 15 member 1transporter
DB00672ChlorpropamideSolute carrier family 15 member 2transporter
DB00672ChlorpropamideSolute carrier family 22 member 6transporter
DB00672ChlorpropamideCytochrome P450 2C9enzyme
DB00672ChlorpropamideCytochrome P450 2C19enzyme
DB00672ChlorpropamideProstaglandin G/H synthase 1enzyme
DB00930ColesevelamBile acidstarget
DB06292DapagliflozinSodium/glucose cotransporter 2target
DB06292DapagliflozinCytochrome P450 1A1enzyme
DB06292DapagliflozinCytochrome P450 1A2enzyme
DB06292DapagliflozinCytochrome P450 2A6enzyme
DB06292DapagliflozinCytochrome P450 2C9enzyme
DB06292DapagliflozinCytochrome P450 2D6enzyme
DB06292DapagliflozinCytochrome P450 3A4enzyme
DB06292DapagliflozinUDP-glucuronosyltransferase 1-9enzyme
DB06292DapagliflozinUDP-glucuronosyltransferase 2B4enzyme
DB06292DapagliflozinUDP-glucuronosyltransferase 2B7enzyme
DB06292DapagliflozinP-glycoprotein 1transporter
DB09045DulaglutideGlucagon-like peptide 1 receptortarget
DB09038EmpagliflozinSodium/glucose cotransporter 2target
DB09038EmpagliflozinUDP-glucuronosyltransferase 2B7enzyme
DB09038EmpagliflozinUDP-glucuronosyltransferase 1-3enzyme
DB09038EmpagliflozinUDP-glucuronosyltransferase 1-8enzyme
DB09038EmpagliflozinUDP-glucuronosyltransferase 1-9enzyme
DB09038EmpagliflozinP-glycoprotein 1transporter
DB09038EmpagliflozinATP-binding cassette sub-family G member 2transporter
DB09038EmpagliflozinSolute carrier family 22 member 8transporter
DB09038EmpagliflozinSolute carrier organic anion transporter family member 1B1transporter
DB09038EmpagliflozinSolute carrier organic anion transporter family member 1B3transporter
DB11827ErtugliflozinUDP-glucuronosyltransferase 1-9enzyme
DB11827ErtugliflozinUDP-glucuronosyltransferase 2B7enzyme
DB11827ErtugliflozinSodium/glucose cotransporter 2target
DB11827ErtugliflozinP-glycoprotein 1transporter
DB11827ErtugliflozinATP-binding cassette sub-family G member 2transporter
DB11827ErtugliflozinSerum albumincarrier
DB11827ErtugliflozinUDP-glucuronosyltransferase 1-1enzyme
DB11827ErtugliflozinUDP-glucuronosyltransferase 1-4enzyme
DB01276ExenatideGlucagon-like peptide 1 receptortarget
DB01276ExenatideSerum albumincarrier
DB01276ExenatideDipeptidyl peptidase 4enzyme
DB01120GliclazideATP-binding cassette sub-family C member 8target
DB01120GliclazideSerum albumincarrier
DB01120GliclazideVascular endothelial growth factor Atarget
DB01120GliclazideCytochrome P450 2C9enzyme
DB01120GliclazideCytochrome P450 2C19enzyme
DB00222GlimepirideATP-sensitive inward rectifier potassium channel 1target
DB00222GlimepirideATP-sensitive inward rectifier potassium channel 11target
DB00222GlimepirideCytochrome P450 2C9enzyme
DB00222GlimepirideATP-binding cassette sub-family C member 8target
DB00222GlimepirideBile salt export pumptransporter
DB01067GlipizideCytochrome P450 2C9enzyme
DB01067GlipizidePeroxisome proliferator-activated receptor gammatarget
DB01067GlipizideATP-binding cassette sub-family C member 8target
DB01067GlipizideUDP-glucuronosyltransferase 1-1enzyme
DB01067GlipizideBile salt export pumptransporter
DB01067GlipizideSerum albumincarrier
DB01251GliquidoneATP-binding cassette sub-family C member 8target
DB01251GliquidoneATP-sensitive inward rectifier potassium channel 8target
DB01251GliquidoneCytochrome P450 2C9enzyme
DB00040GlucagonGlucagon receptortarget
DB00040GlucagonGlucagon-like peptide 2 receptortarget
DB00040GlucagonGlucagon-like peptide 1 receptortarget
DB01016GlyburideATP-binding cassette sub-family C member 9target
DB01016GlyburideBile salt export pumptarget
DB01016GlyburideATP-binding cassette sub-family A member 1target
DB01016GlyburideCystic fibrosis transmembrane conductance regulatortarget
DB01016GlyburideSulfonylurea receptor 1, Kir6.2target
DB01016GlyburideCytochrome P450 2C9enzyme
DB01016GlyburideCanalicular multispecific organic anion transporter 2transporter
DB01016GlyburideBile salt export pumptransporter
DB01016GlyburideP-glycoprotein 1transporter
DB01016GlyburideMultidrug resistance-associated protein 1transporter
DB01016GlyburideSolute carrier family 15 member 1transporter
DB01016GlyburideSolute carrier organic anion transporter family member 1A2transporter
DB01016GlyburideSolute carrier family 15 member 2transporter
DB01016GlyburideSolute carrier family 22 member 6transporter
DB01016GlyburideCanalicular multispecific organic anion transporter 1transporter
DB01016GlyburideATP-binding cassette sub-family G member 2transporter
DB01016GlyburideSolute carrier family 22 member 7transporter
DB01016GlyburideSolute carrier organic anion transporter family member 2B1transporter
DB01016GlyburideCytochrome P450 2C19enzyme
DB01016GlyburideCytochrome P450 3A4enzyme
DB01016GlyburideSerum albumincarrier
DB01016GlyburideMitochondrial ATP-sensitive potassium channeltarget
DB01016GlyburideCarnitine O-palmitoyltransferase 1, liver isoformtarget
DB01016GlyburideCytochrome P450 3A7enzyme
DB01016GlyburideCytochrome P450 3A5enzyme
DB01016GlyburideTransient receptor potential cation channel subfamily M member 4target
DB09564Insulin degludecInsulin receptortarget
DB09564Insulin degludecInsulin-like growth factor 1 receptortarget
DB09564Insulin degludecSerum albumincarrier
DB09564Insulin degludecCytochrome P450 1A2enzyme
DB01307Insulin detemirInsulin receptortarget
DB01307Insulin detemirSerum albumincarrier
DB01307Insulin detemirInsulin-like growth factor 1 receptortarget
DB01307Insulin detemirCytochrome P450 1A2enzyme
DB00047Insulin glargineInsulin receptortarget
DB00047Insulin glargineInsulin-like growth factor 1 receptortarget
DB00047Insulin glargineCytochrome P450 1A2enzyme
DB00046Insulin lisproInsulin receptortarget
DB00046Insulin lisproInsulin-like growth factor 1 receptortarget
DB00046Insulin lisproCytochrome P450 1A2enzyme
DB00046Insulin lisproInsulin-degrading enzymeenzyme
DB08882LinagliptinDipeptidyl peptidase 4target
DB08882LinagliptinCytochrome P450 3A4enzyme
DB08882LinagliptinP-glycoprotein 1transporter
DB08882LinagliptinSolute carrier family 22 member 1transporter
DB08882LinagliptinSolute carrier family 22 member 2transporter
DB08882LinagliptinSolute carrier family 22 member 3transporter
DB00166Lipoic acidLipoyltransferase 1, mitochondrialtarget
DB00166Lipoic acidSodium-dependent multivitamin transportertarget
DB00166Lipoic acidLipoyl synthase, mitochondrialtarget
DB00166Lipoic acidNADPH--cytochrome P450 reductaseenzyme
DB06655LiraglutideGlucagon-like peptide 1 receptortarget
DB06655LiraglutideDipeptidyl peptidase 4enzyme
DB06655LiraglutideNeprilysinenzyme
DB06655LiraglutideSerum albumincarrier
DB09265LixisenatideGlucagon-like peptide 1 receptortarget
DB00331Metformin5'-AMP-activated protein kinase subunit beta-1target
DB00331MetforminSolute carrier family 22 member 2transporter
DB00331MetforminSolute carrier family 22 member 1transporter
DB00331MetforminMultidrug and toxin extrusion protein 1transporter
DB00331MetforminEquilibrative nucleoside transporter 4transporter
DB00331MetforminSolute carrier family 22 member 3transporter
DB00331MetforminMultidrug and toxin extrusion protein 2transporter
DB00331MetforminElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrialtarget
DB00331MetforminGlycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmictarget
DB00491MiglitolMaltase-glucoamylase, intestinaltarget
DB00491MiglitolPancreatic alpha-amylaseenzyme
DB00491MiglitolLysosomal alpha-glucosidasetarget
DB00491MiglitolNeutral alpha-glucosidase ABtarget
DB00491MiglitolNeutral alpha-glucosidase Ctarget
DB01252MitiglinideATP-binding cassette sub-family C member 8target
DB01252MitiglinidePeroxisome proliferator-activated receptor gammatarget
DB01252MitiglinideUDP-glucuronosyltransferase 1-3enzyme
DB01252MitiglinideUDP-glucuronosyltransferase 2B7enzyme
DB00731NateglinideATP-binding cassette sub-family C member 8target
DB00731NateglinideCytochrome P450 3A4enzyme
DB00731NateglinideCytochrome P450 2C9enzyme
DB00731NateglinidePeroxisome proliferator-activated receptor gammatarget
DB00731NateglinideCytochrome P450 3A5enzyme
DB00731NateglinideCytochrome P450 3A7enzyme
DB00731NateglinideSolute carrier family 15 member 1transporter
DB00731NateglinideSolute carrier family 15 member 2transporter
DB00731NateglinideSolute carrier family 22 member 6transporter
DB00731NateglinideMonocarboxylate transporter 1transporter
DB00731NateglinideProstaglandin G/H synthase 1enzyme
DB00731NateglinideUDP-glucuronosyltransferase 1-9enzyme
DB00731NateglinideCytochrome P450 2D6enzyme
DB00731NateglinideMultidrug resistance-associated protein 4transporter
DB00731NateglinideSerum albumincarrier
DB00731NateglinideAlpha-1-acid glycoprotein 1carrier
DB01132PioglitazonePeroxisome proliferator-activated receptor gammatarget
DB01132PioglitazoneCytochrome P450 2C8enzyme
DB01132PioglitazoneCytochrome P450 3A4enzyme
DB01132PioglitazoneSolute carrier organic anion transporter family member 1B3transporter
DB01132PioglitazoneSolute carrier organic anion transporter family member 1B1transporter
DB01132PioglitazoneAmine oxidase [flavin-containing] Btarget
DB01132PioglitazoneSerum albumincarrier
DB01132PioglitazoneCytochrome P450 1A1enzyme
DB01278PramlintideReceptor activity-modifying protein 1target
DB01278PramlintideReceptor activity-modifying protein 2target
DB01278PramlintideReceptor activity-modifying protein 3target
DB01278PramlintideCalcitonin receptortarget
DB00912RepaglinideATP-binding cassette sub-family C member 8target
DB00912RepaglinideCytochrome P450 2C8enzyme
DB00912RepaglinidePeroxisome proliferator-activated receptor gammatarget
DB00912RepaglinideCytochrome P450 3A4enzyme
DB00912RepaglinideSerum albumincarrier
DB00912RepaglinideSolute carrier organic anion transporter family member 1B1transporter
DB00912RepaglinideBile salt export pumptransporter
DB00412RosiglitazonePeroxisome proliferator-activated receptor gammatarget
DB00412RosiglitazoneCytochrome P450 2C8enzyme
DB00412RosiglitazoneCytochrome P450 2C9enzyme
DB00412RosiglitazoneLong-chain-fatty-acid--CoA ligase 4target
DB00412RosiglitazoneSolute carrier organic anion transporter family member 1B1transporter
DB00412RosiglitazoneProstaglandin G/H synthase 1enzyme
DB00412RosiglitazoneCytochrome P450 1A2enzyme
DB00412RosiglitazoneCytochrome P450 2A6enzyme
DB00412RosiglitazoneCytochrome P450 2D6enzyme
DB00412RosiglitazoneSerum albumincarrier
DB00412RosiglitazonePeroxisome proliferator-activated receptor alphatarget
DB00412RosiglitazonePeroxisome proliferator-activated receptor deltatarget
DB00412RosiglitazoneRetinoic acid receptor RXR-alphatarget
DB00412RosiglitazoneRetinoic acid receptor RXR-betatarget
DB00412RosiglitazoneRetinoic acid receptor RXR-gammatarget
DB00412RosiglitazoneCytochrome P450 3A4enzyme
DB00412RosiglitazoneBile salt export pumptransporter
DB06335SaxagliptinDipeptidyl peptidase 4target
DB06335SaxagliptinCytochrome P450 3A4enzyme
DB06335SaxagliptinCytochrome P450 3A5enzyme
DB06335SaxagliptinMultidrug resistance-associated protein 1transporter
DB06335SaxagliptinSolute carrier organic anion transporter family member 4C1transporter
DB06335SaxagliptinSolute carrier family 22 member 8transporter
DB13928SemaglutideSerum albumincarrier
DB13928SemaglutideDipeptidyl peptidase 4enzyme
DB13928SemaglutideNeprilysinenzyme
DB13928SemaglutideGlucagon-like peptide 1 receptortarget
DB13928SemaglutideLipoprotein lipaseenzyme
DB13928SemaglutideAlpha-amylase 1enzyme
DB00641Simvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00641SimvastatinCytochrome P450 3A4enzyme
DB00641SimvastatinCytochrome P450 2C8enzyme
DB00641SimvastatinCytochrome P450 2C9enzyme
DB00641SimvastatinCytochrome P450 3A5enzyme
DB00641SimvastatinP-glycoprotein 1transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1A2transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1B1transporter
DB00641SimvastatinCytochrome P450 2B6enzyme
DB00641SimvastatinCytochrome P450 2D6enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-1enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-3enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 2B7enzyme
DB00641SimvastatinCanalicular multispecific organic anion transporter 1transporter
DB00641SimvastatinIntegrin alpha-Ltarget
DB00641SimvastatinBile salt export pumptransporter
DB00641SimvastatinCytochrome P450 2C19enzyme
DB00641SimvastatinSolute carrier organic anion transporter family member 2B1transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1B3transporter
DB00641SimvastatinHistone deacetylase 2target
DB01261SitagliptinDipeptidyl peptidase 4target
DB01261SitagliptinCytochrome P450 3A4enzyme
DB01261SitagliptinCytochrome P450 2C8enzyme
DB01261SitagliptinP-glycoprotein 1transporter
DB01261SitagliptinSolute carrier family 22 member 8transporter
DB00839TolazamideSulfonylurea receptor 1, Kir6.2target
DB00839TolazamideCytochrome P450 2C9enzyme
DB01124TolbutamideATP-sensitive inward rectifier potassium channel 1target
DB01124TolbutamideCytochrome P450 2C19enzyme
DB01124TolbutamideCytochrome P450 2C9enzyme
DB01124TolbutamideCytochrome P450 2C8enzyme
DB01124TolbutamideATP-binding cassette sub-family C member 8target
DB01124TolbutamideSolute carrier family 15 member 1transporter
DB01124TolbutamideSolute carrier organic anion transporter family member 1A2transporter
DB01124TolbutamideSolute carrier family 15 member 2transporter
DB01124TolbutamideSolute carrier family 22 member 6transporter
DB01124TolbutamideSolute carrier organic anion transporter family member 2B1transporter
DB01124TolbutamideCytochrome P450 2C18enzyme
DB01124TolbutamideSerum albumincarrier
DB00273TopiramateGamma-aminobutyric acid receptor subunit alpha-1target
DB00273TopiramateVoltage-gated sodium channel alpha subunittarget
DB00273TopiramateCarbonic anhydrase 2target
DB00273TopiramateCarbonic anhydrase 4target
DB00273TopiramateKainate receptorstarget
DB00273TopiramateCytochrome P450 2C19enzyme
DB00273TopiramateCytochrome P450 3A4enzyme
DB00273TopiramateCarbonic anhydrase 1target
DB00273TopiramateCarbonic anhydrase 3target
DB00273TopiramateVoltage gated L-type calcium channeltarget
DB00273TopiramateVoltage-dependent R-type calcium channeltarget
DB00273TopiramateSerum albumincarrier
DB00273TopiramateP-glycoprotein 1transporter
DB00273Topiramate5'-AMP-activated protein kinasetransporter
DB04876VildagliptinDipeptidyl peptidase 4target
DB04876VildagliptinP-glycoprotein 1transporter
DB04878VogliboseMaltase-glucoamylase, intestinaltarget
DrugDrug NamePhaseStatusCount
DB06151Acetylcysteine0Completed1
DB00594Amiloride0Terminated1
DB14806Avexitide0Completed1
DB00201Caffeine0Completed1
DB09038Empagliflozin0Recruiting1
DB00999Hydrochlorothiazide0Terminated1
DB00030Insulin human0Completed1
DB00030Insulin human0Not Yet Recruiting1
DB00331Metformin0Completed1
DB00627Niacin0Recruiting1
DB00635Prednisone0Not Yet Recruiting1
DB01261Sitagliptin0Withdrawn1
DB09422Soybean oil0Recruiting1
DB12084ADP-5971Completed3
DB14810AZD-16561Completed16
DB14875AZD-40171Completed1
DB14949AZD-76871Completed1
DB00284Acarbose1Completed4
DB00316Acetaminophen1Completed2
DB09278Activated charcoal1Completed1
DB11704Adomeglivant1Completed4
DB05162Albiglutide1Completed2
DB09043Albiglutide1Completed8
DB08915Aleglitazar1Completed1
DB06203Alogliptin1Completed2
DB00381Amlodipine1Completed1
DB12417Anagliptin1Completed1
DB00125Arginine1Completed1
DB00125Arginine1Withdrawn1
DB14806Avexitide1Completed2
DB05983Bardoxolone methyl1Terminated2
DB05983Bardoxolone methyl1Withdrawn1
DB03995Betadex1Completed1
DB01019Bethanechol1Completed1
DB12236Bexagliflozin1Completed6
DB12236Bexagliflozin1Withdrawn1
DB01200Bromocriptine1Completed1
DB00887Bumetanide1Completed1
DB01156Bupropion1Completed1
DB00201Caffeine1Recruiting1
DB08907Canagliflozin1Completed8
DB08907Canagliflozin1Enrolling by Invitation1
DB00169Cholecalciferol1Completed1
DB11255Chromium picolinate1Terminated1
DB00758Clopidogrel1Recruiting1
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DB11723Dutogliptin3Terminated7
DB15650Efpeglenatide3Completed1
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DB00700Eplerenone3Unknown Status1
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DB12625Evogliptin3Recruiting2
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DB01276Exenatide3Completed53
DB01276Exenatide3Recruiting1
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DB01039Fenofibrate3Completed3
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DB00695Furosemide3Completed1
DB12412Gemigliptin3Completed7
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DB00222Glimepiride3Active Not Recruiting1
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DB00999Hydrochlorothiazide3Completed2
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DB01306Insulin aspart3Active Not Recruiting1
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DB01306Insulin aspart3Recruiting1
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DB01307Insulin detemir3Completed18
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DB00047Insulin glargine3Active Not Recruiting4
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DB00047Insulin glargine3Recruiting6
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DB00030Insulin human3Active Not Recruiting1
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DB00046Insulin lispro3Recruiting2
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DB16209Janagliflozin3Recruiting2
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DB08882Linagliptin3Completed34
DB08882Linagliptin3Not Yet Recruiting2
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DB06655Liraglutide3Active Not Recruiting1
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DB06655Liraglutide3Not Yet Recruiting1
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DB09198Lobeglitazone3Active Not Recruiting1
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DB09198Lobeglitazone3Recruiting2
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DB12055MK-07673Terminated7
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DB00331Metformin3Completed204
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DB06510Muraglitazar3Completed5
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DB00627Niacin3Completed1
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DB00412Rosiglitazone3Terminated4
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DB09292Sacubitril3Suspended1
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DB06335Saxagliptin3Recruiting1
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DB13928Semaglutide3Active Not Recruiting1
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DB05317TAK-4753Completed1
DB04936Tagatose3Completed1
DB06624Taranabant3Terminated1
DB14027Taspoglutide3Completed9
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DB00966Telmisartan3Completed1
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DB11950Teneligliptin3Completed13
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DB15171Tirzepatide3Active Not Recruiting3
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DB09536Titanium dioxide3Active Not Recruiting1
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DB00273Topiramate3Suspended1
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DB00384Triamterene3Completed1
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DB00177Valsartan3Suspended1
DB04876Vildagliptin3Completed68
DB11094Vitamin D3Completed1
DB04878Voglibose3Completed4
DB09321Zinc oxide3Active Not Recruiting1
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DB09321Zinc oxide3Recruiting2
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DB118982,4-thiazolidinedione4Terminated1
DB00284Acarbose4Completed17
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DB00284Acarbose4Terminated2
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DB00316Acetaminophen4Completed1
DB06151Acetylcysteine4Terminated1
DB00945Acetylsalicylic acid4Completed7
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DB00051Adalimumab4Unknown Status1
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DB09026Aliskiren4Completed3
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DB00381Amlodipine4Completed6
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DB00026Anakinra4Terminated1
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DB00335Atenolol4Terminated1
DB01076Atorvastatin4Completed9
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DB00626Bacitracin4Terminated1
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DB11748Benfotiamine4Completed1
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DB05229Beraprost4Completed1
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DB00559Bosentan4Completed2
DB01200Bromocriptine4Completed2
DB01156Bupropion4Completed1
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DB01373Calcium4Unknown Status1
DB08907Canagliflozin4Active Not Recruiting1
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DB13919Candesartan4Recruiting1
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DB01136Carvedilol4Completed1
DB01136Carvedilol4Recruiting1
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DB14256Centella asiatica4Active Not Recruiting1
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DB00356Chlorzoxazone4Completed1
DB00169Cholecalciferol4Completed2
DB11255Chromium picolinate4Completed1
DB01340Cilazapril4Recruiting1
DB01166Cilostazol4Completed4
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DB11672Curcumin4Recruiting1
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DB01914D-glucose4Completed1
DB06695Dabigatran etexilate4Recruiting1
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DB06292Dapagliflozin4Enrolling by Invitation1
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DB09045Dulaglutide4Completed4
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DB09038Empagliflozin4Completed10
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DB00700Eplerenone4Completed1
DB01240Epoprostenol4Completed1
DB00876Eprosartan4Recruiting1
DB11827Ertugliflozin4Not Yet Recruiting2
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DB12625Evogliptin4Enrolling by Invitation1
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DB09303Evolocumab4Recruiting2
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DB01276Exenatide4Not Yet Recruiting3
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DB00099Filgrastim4Completed1
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DB09198Lobeglitazone4Recruiting1
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DB01132Pioglitazone4Active Not Recruiting1
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DB01599Probucol4Completed1
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DB00881Quinapril4Recruiting1
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DB00178Ramipril4Recruiting1
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DB00243Ranolazine4Withdrawn1
DB00912Repaglinide4Completed16
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DB06335Saxagliptin4Completed17
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DB06335Saxagliptin4Terminated3
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DB01261Sitagliptin4Recruiting5
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DB00820Tadalafil4Completed1
DB09161Technetium Tc-99m sestamibi4Completed1
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DB11950Teneligliptin4Recruiting2
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DB06285Teriparatide4Active Not Recruiting1
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DB08816Ticagrelor4Completed3
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DB09536Titanium dioxide4Recruiting1
DB11824Tofogliflozin4Completed2
DB01124Tolbutamide4Completed1
DB00273Topiramate4Recruiting1
DB00193Tramadol4Completed1
DB00519Trandolapril4Recruiting1
DB15323Trelagliptin4Completed3
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DB01586Ursodeoxycholic acid4Unknown Status1
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DB00177Valsartan4Recruiting2
DB00177Valsartan4Unknown Status1
DB00862Vardenafil4Terminated1
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