This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Zotizalkib
- DrugBank Accession Number
- DB19238
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
Structure for Zotizalkib (DB19238)
- Weight
- Average: 447.418
Monoisotopic: 447.151824013 - Chemical Formula
- C21H20F3N5O3
- Synonyms
- 18,1-METHENO-6H-(1,4)OXAZINO(3,4-I)PYRAZOLO(4,3-F)(1,4,8,10)BENZOXATRIAZACYCLOTRIDECIN-15(12H)-ONE, 4-(DIFLUOROMETHYL)-8-FLUORO-3,4,13,14-TETRAHYDRO-13,13-DIMETHYL-, (4S)-
- External IDs
- TPX-0131
- TPX0131
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 5BKJ4Z6RBU
- CAS number
- 2648641-36-3
- InChI Key
- ILAMRXVQSGVCJX-AWEZNQCLSA-N
- InChI
- InChI=1S/C21H20F3N5O3/c1-21(2)10-32-15-4-3-12(22)5-11(15)7-28-14(17(23)24)9-31-16-8-29-18(26-19(16)28)13(6-25-29)20(30)27-21/h3-6,8,14,17H,7,9-10H2,1-2H3,(H,27,30)/t14-/m0/s1
- IUPAC Name
- SMILES
- CC1(C)COC2=CC=C(F)C=C2CN2[C@@H](COC3=CN4N=CC(=C4N=C23)C(=O)N1)C(F)F
References
- General References
- Not Available
- External Links
- ChemSpider
- 115009576
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at July 10, 2024 13:51 / Updated at July 11, 2024 07:56