Duodenal Ulcer

Also known as: Duodenal Ulcer´╝îDU / Duodenal ulceration / Duodenal Ulcer (DU) / Duodenal Ulcers / Gastro-duodenal ulcer / Gastroduodenal Ulcers / Gastroduodenal Ulcer / DU / Unspecified duodenal ulcer NOS (disorder) / Unspecified duodenal ulcer (disorder) / Common duodenal ulcer (disorder) / Duodenal ulcer disease / Duodenal ulcer NOS / Peptic ulcer of duodenum / Ulcer duodenal / Ulcer of duodenum (disorder) / Duodenal ulcer NOS (disorder) / Common duodenal ulcer (disorder) [Ambiguous] / Duodenal ulcer (disorder) / Ulcer gastroduodenal / Peptic ulcer, site unspecified / Peptic ulcer NOS / Peptic ulcer syndrome / Ulcer syndrome peptic / Peptic ulcer disease / Peptic ulcer - (PU) site unspecified (disorder) / Ulcer: [peptic (PU) site unspecified] or [stress NOS] / Syndrome peptic ulcer / PUD / Peptic ulceration / Unspecified peptic ulcer (disorder) / Unspecified peptic ulcer NOS (disorder) / GDU / Ulcer: [peptic NOS] or [gastrojejunal] or [stomal] or [anastomotic] / Peptic ulcer / Peptic ulcer (disorder) / Peptic ulcer NOS (disorder) / Ulcer peptic

DrugDrug NameDrug Description
DB06723Aluminum hydroxideAn antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
DB01294Bismuth subsalicylateAn antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
DB13762DexrabeprazoleA proton pump inhibitor indicated in the treatment of gastroesophageal reflux disease and gastrointestinal ulcers.
DB11074DimethiconeAn ingredient used to treat dry and irritated eyes.
DB00736EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
DB00927FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
DB00448LansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB00585NizatidineAn H2 receptor antagonist used to treat GERD and a variety of ulcers.
DB00338OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
DB00213PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
DB01129RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB00863RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
DB01390Sodium bicarbonateA compound used for the symptomatic treatment of heartburn, acid indigestion, and upset stomach as well as the treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock.
DB00364SucralfateA gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
DB11739VonoprazanA potassium-competitive acid blocker used in the treatment of acid-related disorders and as an adjunct to Helicobacter pylori eradication.
DrugDrug NameTargetType
DB01294Bismuth subsalicylateSerum albumincarrier
DB01294Bismuth subsalicylateSerotransferrincarrier
DB13762DexrabeprazoleCytochrome P450 2C19enzyme
DB00736EsomeprazolePotassium-transporting ATPase alpha chain 1target
DB00736EsomeprazoleCytochrome P450 2C19enzyme
DB00736EsomeprazoleCytochrome P450 3A4enzyme
DB00736EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00736EsomeprazoleP-glycoprotein 1transporter
DB00736EsomeprazoleSolute carrier family 22 member 8transporter
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00927FamotidineMultidrug and toxin extrusion protein 1transporter
DB00927FamotidineCytochrome P450 1A2enzyme
DB00927FamotidineSolute carrier family 22 member 6transporter
DB00448LansoprazolePotassium-transporting ATPase alpha chain 1target
DB00448LansoprazoleCytochrome P450 2C19enzyme
DB00448LansoprazoleCytochrome P450 2C9enzyme
DB00448LansoprazoleCytochrome P450 3A4enzyme
DB00448LansoprazoleP-glycoprotein 1transporter
DB00448LansoprazoleATP-binding cassette sub-family G member 2transporter
DB00448LansoprazoleCytochrome P450 1A1enzyme
DB00448LansoprazoleCytochrome P450 1B1enzyme
DB00448LansoprazoleCytochrome P450 2C18enzyme
DB00448LansoprazoleCytochrome P450 2C8enzyme
DB00448LansoprazoleCytochrome P450 2D6enzyme
DB00448LansoprazoleMicrotubule-associated protein tautarget
DB00448LansoprazoleSolute carrier family 22 member 8transporter
DB00448LansoprazoleSolute carrier family 22 member 1transporter
DB00448LansoprazoleSolute carrier family 22 member 2transporter
DB00448LansoprazoleSolute carrier family 22 member 3transporter
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleP-glycoprotein 1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DB00585NizatidineHistamine H2 receptortarget
DB00585NizatidineP-glycoprotein 1transporter
DB00585NizatidineCholinesteraseenzyme
DB00338OmeprazolePotassium-transporting ATPase alpha chain 1target
DB00338OmeprazoleCytochrome P450 2C19enzyme
DB00338OmeprazoleCytochrome P450 3A4enzyme
DB00338OmeprazoleCytochrome P450 2C9enzyme
DB00338OmeprazoleCytochrome P450 1A2enzyme
DB00338OmeprazoleCanalicular multispecific organic anion transporter 2transporter
DB00338OmeprazoleP-glycoprotein 1transporter
DB00338OmeprazoleATP-binding cassette sub-family G member 2transporter
DB00338OmeprazoleCytochrome P450 1A1enzyme
DB00338OmeprazoleCytochrome P450 1B1enzyme
DB00338OmeprazoleCytochrome P450 2C18enzyme
DB00338OmeprazoleCytochrome P450 2C8enzyme
DB00338OmeprazoleCytochrome P450 2D6enzyme
DB00338OmeprazoleAryl hydrocarbon receptortarget
DB00213PantoprazolePotassium-transporting ATPase alpha chain 1target
DB00213PantoprazoleCytochrome P450 2C19enzyme
DB00213PantoprazoleCytochrome P450 3A4enzyme
DB00213PantoprazoleP-glycoprotein 1transporter
DB00213PantoprazoleATP-binding cassette sub-family G member 2transporter
DB00213PantoprazoleSolute carrier family 22 member 8transporter
DB00213PantoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB01129RabeprazolePotassium-transporting ATPase alpha chain 1target
DB01129RabeprazoleCytochrome P450 3A4enzyme
DB01129RabeprazoleCytochrome P450 2C19enzyme
DB01129RabeprazoleATP-binding cassette sub-family G member 2transporter
DB01129RabeprazoleCytochrome P450 1A1enzyme
DB01129RabeprazoleCytochrome P450 1A2enzyme
DB01129RabeprazoleCytochrome P450 2C9enzyme
DB01129RabeprazoleCytochrome P450 2D6enzyme
DB01129RabeprazoleCytochrome P450 2C8enzyme
DB00863RanitidineHistamine H2 receptortarget
DB00863RanitidineCytochrome P450 1A2enzyme
DB00863RanitidineCytochrome P450 2D6enzyme
DB00863RanitidineSolute carrier family 22 member 1transporter
DB00863RanitidineP-glycoprotein 1transporter
DB00863RanitidineSolute carrier family 22 member 8transporter
DB00863RanitidineCytochrome P450 3A4enzyme
DB00863RanitidineAcetylcholinesterasetarget
DB00863RanitidineSolute carrier family 22 member 2transporter
DB00863RanitidineAcetylcholinesteraseenzyme
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 1transporter
DB01390Sodium bicarbonateSodium bicarbonate cotransporter 3transporter
DB01390Sodium bicarbonateElectroneutral sodium bicarbonate exchanger 1transporter
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 4transporter
DB01390Sodium bicarbonateHydrogen ionstarget
DB01390Sodium bicarbonateSodium-driven chloride bicarbonate exchangertransporter
DB00364SucralfateFibrinogentarget
DB00364SucralfatePepsin A-5target
DB00364SucralfatePro-epidermal growth factortarget
DB00364SucralfateFibroblast growth factor 2target
DB11739VonoprazanHydrogen potassium ATPasetarget
DB11739VonoprazanCytochrome P450 3A4enzyme
DB11739VonoprazanCytochrome P450 3A5enzyme
DB11739VonoprazanCytochrome P450 2B6enzyme
DB11739VonoprazanCytochrome P450 2C19enzyme
DB11739VonoprazanCytochrome P450 2C9enzyme
DB11739VonoprazanCytochrome P450 2D6enzyme
DB11739VonoprazanP-glycoprotein 1transporter
DB11739VonoprazanSerum albumincarrier
DB11739VonoprazanAlpha-1-acid glycoprotein 1carrier
DrugDrug NamePhaseStatusCount
DB11964Ilaprazole2Completed1
DB00338Omeprazole2Completed1
DB01129Rabeprazole2Completed1
DB06151Acetylcysteine2 / 3Unknown Status1
DB01060Amoxicillin2 / 3Unknown Status1
DB01211Clarithromycin2 / 3Unknown Status1
DB08826Deferiprone2 / 3Unknown Status1
DB11964Ilaprazole2 / 3Completed1
DB00331Metformin2 / 3Unknown Status1
DB00916Metronidazole2 / 3Unknown Status1
DB01129Rabeprazole2 / 3Completed1
DB01129Rabeprazole2 / 3Unknown Status1
DB01261Sitagliptin2 / 3Unknown Status1
DB01060Amoxicillin3Unknown Status1
DB01211Clarithromycin3Unknown Status1
DB00736Esomeprazole3Active Not Recruiting1
DB00736Esomeprazole3Completed3
DB12079Gefarnate3Completed1
DB12079Gefarnate3Terminated1
DB11964Ilaprazole3Completed1
DB00448Lansoprazole3Completed7
DB00448Lansoprazole3Recruiting1
DB00448Lansoprazole3Terminated1
DB00448Lansoprazole3Unknown Status1
DB00338Omeprazole3Completed1
DB01129Rabeprazole3Unknown Status1
DB16690Tegoprazan3Recruiting1
DB11739Vonoprazan3Completed8
DB00945Acetylsalicylic acid4Completed1
DB01060Amoxicillin4Completed1
DB00482Celecoxib4Completed1
DB00758Clopidogrel4Completed1
DB00788Naproxen4Completed1
DB00338Omeprazole4Completed1
DB00338Omeprazole4Withdrawn1
DB00945Acetylsalicylic acidNot AvailableUnknown Status1
DB00758ClopidogrelNot AvailableUnknown Status1
DB00338OmeprazoleNot AvailableCompleted1
DB01129RabeprazoleNot AvailableCompleted1
DB01129RabeprazoleNot AvailableUnknown Status1