Pharmaco-genomicsPharmacogenomic Pharmacological Effects and Adverse Drug Reactions

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Displaying entries 4551 - 4575 of 6330 in total

Drug	Interacting Gene/Enzyme	Allele name	Genotypes	Defining change(s)	Type(s)	Description	Details
							Clear
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*38	Not Available	2587_2590delGACT (rs72549351)	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*40	Not Available	1863_1864ins(TTT CGC CCC)2 (rs72549356)	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*42	Not Available	3259_3260insGT (rs72549346)	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*44	Not Available	2950G>C	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*47	Not Available	100C>T (rs1065852) -1426C>T -1235A>G show all 8 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*51	Not Available	-1584C>G -1235A>G -740C>T show all 9 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*56	Not Available	3201C>T (rs72549347)	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*57	Not Available	100C>T 310G>T 843T>G show all 10 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*62	Not Available	4044C>T	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*68A	Not Available	-1426C>T -1235A>G -1000G>A show all 6 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*68B	Not Available	Similar but not identical switch region compared to CYP2D668A. Found in tandem arrangement with CYP2D64.	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*69	Not Available	2988G>A (rs28371725) -1426C>T -1235A>G show all 17 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*92	Not Available	1995delC	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*100	Not Available	-1426C>T -1235A>G -1109C>T show all 15 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*101	Not Available	-1426C>T -1235A>G -1000G>A show all 14 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*9	Not Available	2615-2617delAAG (rs5030656)	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*10	Not Available	100C>T (rs1065852) 1661G>C 4180G>C	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*14B	Not Available	1758G>A (rs5030865)	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*17	Not Available	1023C>T (rs28371706) 2850C>T (rs16947)	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*18	Not Available	4133dupGTGCCCACT	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*29	Not Available	1659G>A 1661G>C 2850C>T show all 5 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*41	Not Available	2988G>A (rs28371725)	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*49	Not Available	100C>T (rs1065852) -1426C>T -1235A>G show all 8 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*50	Not Available	1720A>C	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details
Thioridazine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*54	Not Available	100C>T 1039C>T 1661G>C show all 5 …	ADR Inferred	Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.	Details

Displaying entries 4551 - 4575 of 6330 in total

Pharmaco-genomicsPharmacogenomic Pharmacological Effects and Adverse Drug Reactions

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