Reaction: Aficamten to 3 products
hydroxylationMetabolism of Aficamten
Aficamten is converted to CK‐3834282, CK‐3834283, and CK‐3943037 by Cytochrome P450 2C9, Cytochrome P450 3A4, Cytochrome P450 2D6 and 1 other enzyme.
- Reaction
- Direction
- Activity
- inactive
What you can answer from here — as of January 02, 2026
4EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 2C9, Cytochrome P450 3A4, and Cytochrome P450 2D6, and which of those pairings are clinically significant?
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