Reaction: O-Desmethylnaproxen to 1 product

glucuronidationMajor circulating metaboliteMetabolism of Naproxen

O-Desmethylnaproxen is converted to O-Desmethylnaproxen O-glucuronide by UDP-glucuronosyltransferase 1A1, UDP-glucuronosyltransferase 1A7, UDP-glucuronosyltransferase 1A9 and 1 other enzyme.

Direction

What you can answer from here — as of May 27, 2019

4EnzymesEach linked to its target card
Listed above
1ReferenceThe literature this reaction is curated from
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Which other drugs are metabolised by UDP-glucuronosyltransferase 1A1, UDP-glucuronosyltransferase 1A7, and UDP-glucuronosyltransferase 1A9, and which of those pairings are clinically significant?

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