Reaction: Diclofenac to 1 product
- Reaction
- Reaction type
- glucuronidation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Kuehl GE, Lampe JW, Potter JD, Bigler J: Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes. Drug Metab Dispos. 2005 Jul;33(7):1027-35. doi: 10.1124/dmd.104.002527. Epub 2005 Apr 20. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role UDP-glucuronosyltransferase 2B7 Not Available Not Available confirmed UDP-glucuronosyltransferase 1-3 Not Available Not Available implied UDP-glucuronosyltransferase 1-9 Not Available Not Available implied UDP-glucuronosyltransferase 2B4 Not Available Not Available implied