Reaction: Chloroquine to 1 product

N-dealkylationMajor circulating metaboliteMetabolism of Chloroquine

Chloroquine is converted to (R)-chloroquine, N-desethyl by Cytochrome P450 2C8, Cytochrome P450 2D6, Cytochrome P450 3A4 and 1 other enzyme.

Direction
Activity
active

What you can answer from here — as of March 06, 2020

4EnzymesEach linked to its target card
Listed above
6ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 2C8, Cytochrome P450 2D6, and Cytochrome P450 3A4, and which of those pairings are clinically significant?

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