Reaction: Beclomethasone dipropionate to 2 products
- Reaction
- Reaction type
- hydrolysis
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- Yes
- Activity
- active
- References
- Wurthwein G, Rohdewald P: Activation of beclomethasone dipropionate by hydrolysis to beclomethasone-17-monopropionate. Biopharm Drug Dispos. 1990 Jul;11(5):381-94. [Article]
- Foe K, Cheung HT, Tattam BN, Brown KF, Seale JP: Degradation products of beclomethasone dipropionate in human plasma. Drug Metab Dispos. 1998 Feb;26(2):132-7. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 3A4 Not Available Not Available implied Cytochrome P450 3A5 Not Available Not Available implied Cytochrome P450 3A43 Not Available Not Available implied Cytochrome P450 3A7 Not Available Not Available implied
