Reaction: Apomorphine to 1 product

Reaction
Apomorphine
DB00714
Norapomorphine
DBMET03133
Reaction type
N-demethylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Argiolas A, Hedlund H: The pharmacology and clinical pharmacokinetics of apomorphine SL. BJU Int. 2001 Oct;88 Suppl 3:18-21. doi: 10.1046/j.1464-4096.2001.00124.x. [Article]
  2. FDA Approved Drug Products: Apomorphine Subcutaneous Injection [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2B6Not AvailableNot Availableconfirmed
Cytochrome P450 2C8Not AvailableNot Availableconfirmed
Cytochrome P450 3A4Not AvailableNot Availableconfirmed
Cytochrome P450 3A5Not AvailableNot Availableconfirmed