Reaction: Valproic acid to 1 product
- Reaction
- Reaction type
- 5-hydroxylation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M: KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res. 2012 Jan;40(Database issue):D109-14. doi: 10.1093/nar/gkr988. Epub 2011 Nov 10. [Article]
- Thorn CF, Klein TE, Altman RB: PharmGKB: the Pharmacogenomics Knowledge Base. Methods Mol Biol. 2013;1015:311-20. doi: 10.1007/978-1-62703-435-7_20. [Article]
- Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 3A5 Not Available Not Available implied Cytochrome P450 2A6 Not Available Not Available confirmed Cytochrome P450 2C9 Not Available Not Available confirmed Cytochrome P450 2B6 Not Available Not Available confirmed