Reaction: Macitentan to 1 product
dealkylation; hydroxylationMetabolism of Macitentan
Macitentan is converted to M7 (Macitentan) by Cytochrome P450 2C9, Cytochrome P450 2C8, and Cytochrome P450 2C19.
- Reaction
- Direction
- Activity
- inactive
What you can answer from here — as of November 24, 2021
3EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 2C9, Cytochrome P450 2C8, and Cytochrome P450 2C19, and which of those pairings are clinically significant?
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