Reaction: M2 iptacopan to 1 product

O-glucuronidationMetabolism of Iptacopan

M2 iptacopan is converted to M9 iptacopan by UDP-glucuronosyltransferase 1A1, UDP-glucuronosyltransferase 1A3, and UDP-glucuronosyltransferase 1A8.

Direction
Not Available
Activity
inactive

What you can answer from here — as of December 06, 2023

3EnzymesEach linked to its target card
Listed above

Which other drugs are metabolised by UDP-glucuronosyltransferase 1A1, UDP-glucuronosyltransferase 1A3, and UDP-glucuronosyltransferase 1A8, and which of those pairings are clinically significant?

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