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Displaying results 91 - 100 of 173 in total
  1. Drug

    Omapatrilat

    go.drugbank.com/drugs/DB00886
    Experimental

    Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE). The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating b...

    Categories: Agents Acting on the Renin-Angiotensin System
  2. Drug

    Sodium fluoride

    go.drugbank.com/drugs/DB09325
    ApprovedInvestigational

    Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health...

    Products: Pcxx Remin 0.4
  3. Drug

    Spironolactone

    go.drugbank.com/drugs/DB00421
    ApprovedInvestigational

    Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed pur...

  4. Drug

    Niacin

    go.drugbank.com/drugs/DB00627
    ApprovedInvestigationalNutraceutical

    Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.

  5. Drug

    Terlakiren

    go.drugbank.com/drugs/DB20615
    Experimental

    The usage of the INN stem '-kiren' in the name indicates that Terlakiren is a renin inhibitor. Terlakiren has a monoisotopic molecular weight of 620.32 Da.

  6. Drug

    Saprisartan

    go.drugbank.com/drugs/DB01347
    Experimental

    Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan...

    Categories: Agents Acting on the Renin-Angiotensin System
  7. Drug

    Aprocitentan

    go.drugbank.com/drugs/DB15059
    ApprovedInvestigational

    Approximately 10-15% of patients with hypertension have resistant hypertension, defined as uncontrolled high blood pressure despite the combined use of a renin-angiotensin system blocker, a calcium channel

  8. Drug

    Zankiren

    go.drugbank.com/drugs/DB20787
    Experimental

    The usage of the INN stem '-kiren' in the name indicates that Zankiren is a renin inhibitor. Zankiren has a monoisotopic molecular weight of 705.36 Da.

  9. Drug

    Imarikiren

    go.drugbank.com/drugs/DB19464
    Investigational

    The usage of the INN stem '-kiren' in the name indicates that Imarikiren is a renin inhibitor. Imarikiren has a monoisotopic molecular weight of 499.32 Da.

  10. Drug

    Carbopol 974P

    go.drugbank.com/drugs/DB05384
    ApprovedWithdrawn

    Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. It was under development by ReProtect LLC. It is a gel that may help bo...

    Categories: Resins, Synthetic