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Displaying results 91 - 100 of 35175 in total
  1. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    [A4269,A183842] Tramadol has also been shown to affect a number of other pain modulators within the central nervous system as well as non-neuronal inflammatory markers and immune mediators. … It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of [morphine].

    Mixtures: Ag-acet-tramadol, ONEMER DTCategories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  2. Drug

    NYX-2925

    go.drugbank.com/drugs/DB19149
    Investigational

    NYX-2925 is under investigation in clinical trial NCT04146896 (Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy (DPN)).

  3. Drug

    Potassium chloride

    go.drugbank.com/drugs/DB00761
    ApprovedInvestigationalWithdrawn

    A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. … The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release

    Mixtures: INYECCION DE DEXTROSA AL 5% CLORURO DE POTASIO (20 MEG) Y CLORURO DE SODIO AL 0.2 %, CLORURO DE POTASIO 20 mEq EN DEXTROSA AL 5% Y CLORURO DE SODIO AL 0.45% BAXTERSynonyms: Chloride of potash, Muriate of potash
  4. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Products: Regaine 5 % Schaum zur Anwendung auf der Kopfhaut, Alopexy 50 mg/ml Lösung zur Anwendung auf der Haut
  5. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities.

    Mixtures: TUSBRON-A JARABE, THEOLONG 600/200 MG EFERVESAN TABLET, 10 ADETCategories: combinations of xanthines, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index
  6. Drug

    Levetiracetam

    go.drugbank.com/drugs/DB01202
    ApprovedInvestigational

    make it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders.

    Products: Ran-levetiracetam, Van-levetiracetam
  7. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose deaths).[L6748] Opioid overdoses kill an average of 11 Canadians daily. … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: CITRATO DE FENTANILO 0.05MG/ML, Ran-fentanyl Matrix Patch
  8. Drug

    Dexamethasone

    go.drugbank.com/drugs/DB01234
    ApprovedInvestigationalVet approved

    Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms

    Mixtures: Dex-Moxi PF, GENTA-DEX EYE DROPSCategories: Inducers of Drug Clearance, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  9. Drug

    Ginkgo biloba

    go.drugbank.com/drugs/DB01381
    ApprovedInvestigationalNutraceutical

    [A232379] _Ginkgo folium_, the leaf extract of _Ginkgo biloba_, is considered an anti-dementia drug by the World Health Organization.[A232389] … [L32789] _Ginkgo biloba_ is an herbal plant that is now cultivated worldwide. It is originally native to China, and _ginkgo biloba_ extract has been used in traditional Chinese medicine for centuries.

    Mixtures: Ultra Eye Therapy Drops, DOMINGO 10/10/80 MG EFERVESAN TABLET, 30 ADETCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  10. Drug

    Cyclopentolate

    go.drugbank.com/drugs/DB00979
    Approved

    A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.

    Products: Ak-pentolate, CICLOPENTOLATO AL 1 %