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Leucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigational[L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic … Leucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis.
Mixtures: FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADET, KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK.Categories: Compounds used in a research, industrial, or household settingGinkgo biloba
go.drugbank.com/drugs/DB01381ApprovedInvestigationalNutraceuticaldiseases, such as dementia. … Lactones include ginkgolide A, ginkgolide B, ginkgolide C, bilobalide, and ginkgotoxin, a lactone that is structurally related to [pyridoxine].
Mixtures: DOMINGO 10/10/80 MG EFERVESAN TABLET, 30 ADET, DOMINGO 10/10/80 MG EFERVESAN TABLET, 90 ADETCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 CYP3A InducersTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigationalTapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: PALEXIS® RETARD 150 MG, Nucynta ER Tablets 150 mgCromoglicic acid
go.drugbank.com/drugs/DB01003ApprovedInvestigationalA chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. … It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Products: ALLERGOCROM NAZAL SPREY, 15 ML, ALLERGO COMOD %2 15 ML NAZAL SPREYAscorbic acid
go.drugbank.com/drugs/DB00126ApprovedInvestigationalNutraceuticalIts biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant. … A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables.
Mixtures: EVİNA E+C 100 IU/500 MG YUMUŞAK KAPSÜL, 20 ADET, VİTEROL-D3 PLUS 2000 IU+ 3333 IU+70 MG/ML ORAL DAMLA, ÇÖZELTİ, 20 MLCategories: Compounds used in a research, industrial, or household settingValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigational[A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. … a similar degree of anticonvulsive activity.
Mixtures: PROKSIVAL XR 300 MG UZUN ETKILI FILM TABLET, 50 ADET, PROKSIVAL XR 300 MG UZUN ETKILI FILM TABLET, 50 ADETCategories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexNintedanib
go.drugbank.com/drugs/DB09079ApprovedInvestigationalsuch is used as a first-line treatment following diagnosis to slow down the progressive loss of lung function. … [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved for patients who have tried and failed first-line chemotherapeutic options.[L8459]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: OFEV 150 MG, OFEV® 150 MGMetamizole
go.drugbank.com/drugs/DB04817ApprovedInvestigationalWithdrawn[A251885] Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to its association with potentially fatal agranulocytosis … Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability.
Mixtures: DIPIRONA 300 MG + ISOMETEPTENO 50 MG + CAFEINA 30 MG GOTAS, DIPIRONA SODICA 300 MG/ ISOMETEPTENO CLORHIDRATO 50 MG / CAFEINA 30 MG GOTASCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP3A InducersLactulose
go.drugbank.com/drugs/DB00581ApprovedInvestigationalLactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic … Organization's List of Essential Medicines as one of the most effective and safe medicines employed in a health system[L6205], data regarding its optimal place in therapy is often ambiguous.
Synonyms: 4-O-beta-D-Galactopyranosyl-D-fructose, 4-O-beta-D-Galactopyranosyl-D-fructofuranoseProducts: LACTULOSE AL SIRUP, ORALAC 670 MG/ML ŞURUP, 150 MLNaproxen
go.drugbank.com/drugs/DB00788ApprovedInvestigationalVet approvedNaproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. … [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile.
Mixtures: TIYOKSEN 550 MG/8 MG FILM TABLET,10 ADET, APRANAX PLUS 550 MG/30 MG FILM KAPLI TABLET, 10 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates