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Displaying results 991 - 1000 of 10000 in total
  1. Drug

    Vitamin D

    go.drugbank.com/drugs/DB11094
    ApprovedInvestigationalNutraceuticalVet approved

    Since vitamin D can be endogenously synthesized in adequate amounts by most mammals exposed to sufficient quantities of sunlight, vitamin D functions like a hormone on vitamin D receptors to regulate calcium … Vitamin D plays an essential physiological role in maintaining calcium homeostasis and metabolism.

    Synonyms: Vitamin D NOS, D VitaminMixtures: Super Daily No 2, Multi Plex I - Tab
  2. Drug

    Dinoprostone

    go.drugbank.com/drugs/DB00917
    ApprovedInvestigational

    As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour. … Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts.

    Synonyms: (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid, (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acidInternational brands: Prostarmon E
  3. Drug

    Enflurane

    go.drugbank.com/drugs/DB00228
    ApprovedVet approvedWithdrawn

    Enflurane is a halogenated inhalational anesthetic initially approved by the FDA in 1972. Since this date, it has been withdrawn from the US market. … In addition, it is known to cause increased cardio depressant effects when compared to other inhaled anesthetics.[A202022]

    Synonyms: 2-chloro-1,1,2-trifluoroethyl difluoromethyl etherCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Substrates
  4. Drug

    Levodopa

    go.drugbank.com/drugs/DB01235
    ApprovedInvestigational

    Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after … The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975[A177781,L6133].

    Mixtures: LEVODO CA E P100/25/200, LEVODO CA E P100/25/200Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    Magnesium oxide

    go.drugbank.com/drugs/DB01377
    ApprovedInvestigational

    Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. … It is used as an antacid and mild laxative and has many nonmedicinal uses.

    Mixtures: Super Daily No 2, Cal-mag Plus K, Mn and Zn CapletsProducts: MAGNEZI KALSINE 100 G TOZ, 100 G
  6. Drug

    Quetiapine

    go.drugbank.com/drugs/DB01224
    ApprovedInvestigational

    Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. … It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189]

    Synonyms: 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolMixtures: Quetialan 4 Tage Startpackung - Filmtabletten, Seroquel 4-Tage Startpackung Filmtabletten
  7. Target

    Cytochrome c oxidase subunit 1

    go.drugbank.com/bio_entities/BE0003895
    TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

    Synonyms: Cytochrome c ba(3) subunit I, Cytochrome c oxidase polypeptide I
  8. Target

    Cytochrome c oxidase subunit 1

    go.drugbank.com/bio_entities/BE0003899
    TargetThermus thermophilus

    Synonyms: Cytochrome c ba(3) subunit I, Cytochrome c oxidase polypeptide I
  9. Drug

    Rivaroxaban

    go.drugbank.com/drugs/DB06228
    ApprovedInvestigational

    However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Nb-rivaroxaban, RIBEX® 15 MG
  10. Drug

    Aluminum chloride

    go.drugbank.com/drugs/DB11081
    ApprovedInvestigational

    It may also be found in over-the-counter as an antiperspirant or prescription products as an antihemorrhagic agent. … In antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15%, calculated on the hexahydrate form, in an aqueous solution nonaerosol dosage form [L2012].

    Mixtures: Sulpak II, Anti-perspirant Roll-ON DeodCategories: Compounds used in a research, industrial, or household setting