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Oxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigational[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics … Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.
Products: ENDOCODIL IR, Ran-oxycodone CRAOC 1001
go.drugbank.com/drugs/DB18620InvestigationalDelpacibart (AOC 1001) is being investigated in a global study for the treatment of Myotonic Dystrophy type 1 (DM1) in clinical trial NCT06411288
Synonyms: Immunoglobulin G1 [233-alanine,234-alanine,327-arginine,de-446-lysine], anti-(human type 1 transferrin receptor) (human-Mus musculus clone AV05 γ1-chain), disulfide with human-Mus musculus clone AV05 κ-chainTalbutal
go.drugbank.com/drugs/DB00306ApprovedIllicitTalbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.
Camphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnCamphor is a bicyclic monoterpene ketone found widely in plants, especially _Cinnamomum camphora_. It is used topically as a skin antipruritic and as an anti-infective agent. … [A254252,L43942] However, camphor can be found in several nonprescription medications at lower concentrations.[A254252]
Mixtures: Kaz Inhalant, Au Kah Chuen Skin LotionEncainide
go.drugbank.com/drugs/DB01228ApprovedWithdrawnEncainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. … The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IcCarglumic acid
go.drugbank.com/drugs/DB06775ApprovedInvestigationalCarglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. … This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death.
Zilovertamab
go.drugbank.com/drugs/DB18403InvestigationalSynonyms: Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa.-chain, dimerFusidic acid
go.drugbank.com/drugs/DB02703ApprovedInvestigationalAn antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. … It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Products: STAFINE 500 MG IV INFUZYON ICIN TOZ VE COZUCU ICEREN FLAKONButabarbital
go.drugbank.com/drugs/DB00237ApprovedIllicitWithdrawn[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. … Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.
Sabatolimab
go.drugbank.com/drugs/DB16322InvestigationalSabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic
Synonyms: Immunoglobulin g4 (226-proline,de-c-terminal-lysine), anti-(human hepatitis virus a cellular receptor 2) (human-mus musculus monoclonal clone nvs260714 .gamma.4-chain), disulfide with human-mus musculus, Immunoglobulin g4-kappa, anti-(homo sapiens havcr2 (hepatitis a virus cellular receptor 2, t-cell immunoglobulin mucin family member 3, tim-3, tim3, timd3, cd366)), humanized monoclonal antibody