Search
Basiliximab
go.drugbank.com/drugs/DB00074ApprovedInvestigationalA recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also … to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R
Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking AntibodyProducts: SIMULECT FOR INJECTION 20 mg/vial, SIMULECT® LIOFILIZADO PARA INYECCION 20 MG/VIALLevodropropizine
go.drugbank.com/drugs/DB12472InvestigationalLevodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
Mixtures: PULMOTUS 30 MG+ 2 MG/5 ML ŞURUP, 150 ML, DROPOLEV ŞURUP ,150 MLProducts: LEVOPRONT 60 MG TABLET, 20 ADET, LEVOPRONT SYRUP 60 mg/10 mlGalectin-10
go.drugbank.com/bio_entities/BE0001886TargetHumansRegulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg)
Polypeptides: Galectin-10Synonyms: Gal-10Frizzled-10
go.drugbank.com/bio_entities/BE0020969TargetHumansReceptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclea...
Polypeptides: Frizzled-10Synonyms: Fz-10Bosutinib
go.drugbank.com/drugs/DB06616ApprovedInvestigational[L48436] On September 26, 2023, bosutinib was also approved by the FDA for the treatment of pediatric CML that is newly diagnosed or resistant/intolerant to prior therapy.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrileChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalChlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventi...
Mixtures: TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET, BRASARTAN® CTDN 160/25 MGCategories: Heterocyclic Compounds, 2-RingInterleukin-10
go.drugbank.com/bio_entities/BE0002484TargetHumansMajor immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetram...
Polypeptides: Interleukin-10Synonyms: IL-10Aquaporin-10
go.drugbank.com/bio_entities/BE0018706TransporterHumansAquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed:11573934, PubMed:12084581, PubMed:217338...
Polypeptides: Aquaporin-10Synonyms: AQP-10, Aquaglyceroporin-10Lorlatinib
go.drugbank.com/drugs/DB12130ApprovedInvestigationalLorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA...
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: LORBRENA® 25 MG, LORBRENA® 100 MGMoclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalA reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficaci...
Synonyms: 4-Chlor-N-(2-morpholinoethyl)benzamid, p-Chloro-N-(2-morpholinoethyl)benzamideProducts: AURORIX 150 MG FILM KAPLI TABLET, 30 ADET, AURORIX 300 MG FILM KAPLI TABLET, 30 ADET