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Displaying results 991 - 1000 of 10000 in total
  1. Drug

    European pilchard

    go.drugbank.com/drugs/DB10622
    Approved

    European pilchard allergenic extract is used in allergenic testing.

    Synonyms: European pilchard
  2. Drug

    Pasireotide

    go.drugbank.com/drugs/DB06663
    ApprovedInvestigational

    Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)
  3. Drug

    Methylprednisolone

    go.drugbank.com/drugs/DB00959
    ApprovedInvestigationalVet approved

    Methylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone].[A188811] It was first described in the literature in the late 1950s. … [L10785] In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression.

    Mixtures: Point Of Care LM DEP 2, Dyural L KitCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inducers
  4. Drug

    Galantamine

    go.drugbank.com/drugs/DB00674
    ApprovedInvestigational

    [L13571] It is therefore not considered to be a disease-modifying drug. … Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: REMINYL ®ER CAPSULAS DE 8 MG, REMINYL® SOLUCION ORAL DE 4 MG/ML
  5. Drug

    Aluminum zirconium octachlorohydrex gly

    go.drugbank.com/drugs/DB11200
    Approved

    It is an active antiperspirant agent [L2705], [L2706]. It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores.

    Mixtures: Ron 2Products: Secret Clinical Clear Ooh La La Lavender, Secret Clinical Strength Ooh La La Lavender
  6. Drug

    Trimebutine

    go.drugbank.com/drugs/DB09089
    ApprovedInvestigational

    Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries. … Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects.

    Synonyms: 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoatInternational brands: Shuang Di, Yuan Sheng Li Wei
  7. Drug

    Exenatide

    go.drugbank.com/drugs/DB01276
    ApprovedInvestigational

    Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. … It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension, was discontinued in 2021.

    Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsSynonyms: Exendin 4, Exendin-4
  8. Drug

    Mavacamten

    go.drugbank.com/drugs/DB14921
    ApprovedInvestigational

    Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans.

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesSynonyms: 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dione
  9. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. … It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
  10. Drug

    Aluminum sesquichlorohydrate

    go.drugbank.com/drugs/DB11108
    Approved

    Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts [A31171].

    Mixtures: Lactovit DEO ROLL-ON LACTOUREA DEODORANT ANTIPERSPIRANT, Lactovit DEO ROLL ON LACTOUREA DEODORANT ANTIPERSPIRANTProducts: Pur Desir De Lys Creme Deodorante Antisudorifique, esika D ARIEN CLASS Roll-on