Search
Teplizumab
go.drugbank.com/drugs/DB06606ApprovedInvestigational[A241480] On November 2022, teplizumab was approved by the FDA as the first drug that can delay the onset of type 1 diabetes. … [A241490] Anti-CD3 therapy has traditionally been used to prevent graft-versus-host-disease in organ transplantation but more recently has been explored to prolong the onset of (T1D) in high-risk patients
Ethinamate
go.drugbank.com/drugs/DB01031ApprovedIllicitWithdrawnLike many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a patient. … Structurally, it does not resemble the barbituates, but it shares many effects with this class of drugs; the depressant effects of ethinamate are, however, generally milder than those of most barbiturates
Amlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_. … Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), an important vasodilator that decreases blood pressure [A175321].
Mixtures: EXFORGE® 10/320 COMPRIMIDOS CON CUBIERTA PELICULAR, EXFORGE® 5/80 MG COMPRIMIDOS CON CUBIERTA PELICULARProducts: AMLODIPINA RK, Van-amlodipineHydroxyproline
go.drugbank.com/drugs/DB08847ApprovedTherapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds.
Mixtures: Soo Rye Han Dabityun Jiyun Foundation 21, Soo Rye Han Dabityoon Jiyoon Foundation 23Ulipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalThe exact mechanism of action for ulipristal is still currently debated, though there is evidence that it functions by inhibiting ovulation. … A recent systematic review proclaimed that the majority of available evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily
Regadenoson
go.drugbank.com/drugs/DB06213ApprovedInvestigationalRegadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Olanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigational[A177011] Olanzapine was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.[T548] … Olanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent.
Products: Ran-olanzapine, Van-olanzapineTretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceutical[A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism.
Mixtures: AE BAN CREMAProducts: AK - NE NO CREMAParaldehyde
go.drugbank.com/drugs/DB09117ApprovedWithdrawnParaldehyde is used as an ingredient in some cough medicines as an expectorant, but its efficacy for this indication has not been confirmed and its use as an expectorant may possibly be due to a placebo … Paraldehyde was initially introduced into medical practice in the United Kingdom in 1882 by the Italian physician Vincenzo Cervello.
Netilmicin
go.drugbank.com/drugs/DB00955ApprovedNetilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. … Netilmicin inhibits protein synthesis in susceptible organisms by binding to the bacterial 30S ribosomal subunit and interfering with mRNA binding and the acceptor tRNA site.