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Nuclear factor NF-kappa-B
go.drugbank.com/bio_entities/BE0004903TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family.
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Glucosamine
go.drugbank.com/drugs/DB01296Approved[A231894,A232289] It is currently not approved as a prescription product by the FDA, but is widely available over the counter. … Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation.
Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderProducts: Procosa II Tablet, Nn Bio-Glucosamine 500 TabletTick-Borne Encephalitis, European
go.drugbank.com/conditions/DBCOND0144103Synonyms: Tick-Borne Encephalitis, EuropeanValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigationalIt is currently a compound of interest in the field of oncology for its anti-proliferative effects and is the subject of many clinical trials in a variety of cancer types. … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton.
Synonyms: 2-n-propyl-n-valeric acid, n-DPAMixtures: Depakine Chronosphere 50 mg Retardgranulat in Beuteln, Depakine Chronosphere 50 mg Retardgranulat in BeutelnSildenafil
go.drugbank.com/drugs/DB00203ApprovedInvestigationalin some countries [L5656]. … the public in 1998 [A175732], continues to see millions of prescriptions written for it internationally.
Categories: Drugs Used in Erectile DysfunctionProducts: EROS INN 50 MG TABLETAS, SILDENAFIL IG FARMACEUTICIEstradiol
go.drugbank.com/drugs/DB00783ApprovedInvestigationalVet approvedEstradiol is a naturally occurring hormone circulating endogenously in females. … It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes.
Mixtures: KLIOGEST N, KLIOGEST NProducts: AKROFOLLINE 5 MG/ML IM AMPULLonapegsomatropin
go.drugbank.com/drugs/DB16220ApprovedInvestigational[L36380,L10971] Lonapegsomatropin was granted FDA approval on 25 August 2021.[L36380] It was later approved by the European Commission on 13 January 2022.[L39900] … Lonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth hormone ([somatropin]) indicated for the treatment of children 1 year and older, weighing at least
Serine/threonine-protein kinase Nek9
go.drugbank.com/bio_entities/BE0009500TargetHumansPleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation (PubMed:12101123, PubMed:12840024, PubMed:14660563, PubMed:19941817).
Synonyms: Never in mitosis A-related kinase 9Glofitamab
go.drugbank.com/drugs/DB16371ApprovedInvestigational) after two or more lines of systemic therapy. … , after two or more lines of systemic therapy under accelerated approval based on response rate and durability of response.
Serine/threonine-protein kinase Nek2
go.drugbank.com/bio_entities/BE0003796TargetHumansProtein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells. … Involved in the regulation of centrosome disjunction (PubMed:26220856).
Synonyms: Never in mitosis A-related kinase 2