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Pentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnIt is formed by reacting pentaerythritol (C5H12O4), an alcohol commonly used in paints and varnishes, with nitric acid (HNO2). The reacting solution is chilled to precipitate the PETN. … It is recognized by the FDA to be a coronary vasodilator in the treatment of heart conditions such as angina [L2395].
Categories: Vasodilators Used in Cardiac DiseasesProducts: Peritrate Tab 10mg, Peritrate Tab 20mgLipoic acid
go.drugbank.com/drugs/DB00166ApprovedInvestigationalNutraceuticalA vitamin-like antioxidant.
Mixtures: Folic-KCategories: Compounds used in a research, industrial, or household setting, Enzymes and CoenzymesGonadorelin
go.drugbank.com/drugs/DB00644ApprovedInvestigationalVet approvedGnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary. … Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis.
Mixtures: Relisorm 500 for Inj.-pws Liq-kit IV Sc, Relisorm 100 for Inj.-pws Liq-kit Sc IVCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsEftrenonacog alfa
go.drugbank.com/drugs/DB11608ApprovedEftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. … It is an X-linked genetic disease caused by mutation of the gene for coagulation protein factor IX (FIX), leading to decreased levels of endogenous factor IX and increased susceptibility to recurrent bleeding
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: Recombinant human coagulation factor IX, FC Fusion protein, Coagulation factor IX recombinant immunoglubulin g1 fusion proteinPindolol
go.drugbank.com/drugs/DB00960ApprovedInvestigational[L32353] Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. … Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension.
Categories: pindolol and other diureticsProducts: Apo-pindol Tab 10mg, Nu-pindol Tab 10mgMembrane protein involved in aromatic hydrocarbon degradation
go.drugbank.com/bio_entities/BE0003979TargetPseudomonas putida (strain F1 / ATCC 700007)Polypeptides: Membrane protein involved in aromatic hydrocarbon degradationGadodiamide
go.drugbank.com/drugs/DB00225ApprovedInvestigational[A263101] However, since linear, non-ionic GBCA is less stable than macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and thus more likely to cause side … [A263096] Approved by the FDA in 1993, gadodiamide is the first non-ionic GBCA to be used.
Categories: Compounds used in a research, industrial, or household settingProducts: OMNISCAN INJECTION 0.5MMOL/ML-10ML IN GLASS VIAL, OMNISCAN INJECTION 0.5MMOL/ML-20ML IN GLASS VIALIndocyanine green acid form
go.drugbank.com/drugs/DB09374ApprovedInvestigationalIndocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. … The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,
Mixtures: IC-Green, IC-GreenCategories: Compounds used in a research, industrial, or household settingTelmisartan
go.drugbank.com/drugs/DB00966ApprovedInvestigationalTelmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. … smooth muscle, ultimately leading to a reduction in arterial blood pressure.
Mixtures: TWYNSTA 40MG/10MG, TWYNSTA 40MG/10MGCategories: Angiotensin II receptor blockers (ARBs) and diuretics, Angiotensin II receptor blockers (ARBs) and calcium channel blockersInterferon alfa-2a
go.drugbank.com/drugs/DB00034ApprovedInvestigationalWithdrawnIt is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences. … A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes.
Categories: Amino Acids, Peptides, and Proteins, Interferon Type IProducts: ROFERON - A ROCHE SOLUCION INYECTABLE 3 K/U.I., Roferon-A Sol Inj 3million Iu/vial