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Morphine
go.drugbank.com/drugs/DB00295ApprovedInvestigational[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol, (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diolVancomycin
go.drugbank.com/drugs/DB00512ApprovedInvestigationalIt is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. … Such an oral liquid formulation is expected to make _Clostridium difficile_ associated diarrhea therapy more accessible in comparison to previously available specialty compounding products [LP1196].
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: INJOVAN®500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE, INJOVAN®1000 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLECandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalIt may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease. … Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension.
Mixtures: Ag-candesartan HCT, Ag-candesartan HCTCategories: Angiotensin 2 Receptor Blocker, P-glycoprotein inhibitorsBisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigationalBisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]
Synonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, Dyrax-Q TabStannous fluoride
go.drugbank.com/drugs/DB11092ApprovedInvestigationalStannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. … It is an FDA-approved over-the-counter product.
Categories: Compounds used in a research, industrial, or household settingProducts: Crest Pro-Health With a Touch of Scope, Crest Pro Health with a Touch of ScopeIron sucrose
go.drugbank.com/drugs/DB09146ApprovedInvestigationalIron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis
Mixtures: Marnatal FInternational brands: Ferosoft SMembrane-bound lytic murein transglycosylase B
go.drugbank.com/bio_entities/BE0001578TargetEscherichia coli (strain K12)May play a role in recycling of muropeptides during cell elongation and/or cell division.
Polypeptides: Membrane-bound lytic murein transglycosylase BSynonyms: 35 kDa soluble lytic transglycosylaseIpratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigationalIpratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent. … [A176939] It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption.
Mixtures: BERODUAL® HFA, BERODUAL® HFAProducts: A-TROFINSA, Aa-ipraventMineral oil
go.drugbank.com/drugs/DB11057ApprovedInvestigationalVet approvedMineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum. … It is also used as a mild laxative for human or veterinary uses.
Mixtures: AGAROL CON SABOR A FRAMBUESA, Preparation HProducts: Gelee Laxative A LA Framboise, LAXAROL ORAL EMULSION 50% v/vMontmorillonite
go.drugbank.com/drugs/DB13654InvestigationalCategories: Compounds used in a research, industrial, or household settingProducts: IMPIDEM® POLVO PARA RECONSTITUIR A SOLUCION ORAL, DIOSMECTITA 3 G POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL