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alpha-Linolenic acid
go.drugbank.com/drugs/DB00132ApprovedInvestigationalNutraceuticalWithdrawnAlpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Mixtures: PRIM E CAPSULETechnetium Tc-99m mebrofenin
go.drugbank.com/drugs/DB09137ApprovedWithdrawnLiver and gallbladder imaging is enabled through attachment to mebrofenin as this molecule has high hepatic uptake and fast biliary excretion, resulting in improved hepatic imaging. … This is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray.
Synonyms: Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetiumGilteritinib
go.drugbank.com/drugs/DB12141ApprovedInvestigationalThis drug was approved after being designed as an orphan drug with a fast track and priority review status.[L4830] … [A40044] Gilteritinib was developed by Astellas Pharma and FDA approved on November 28, 2018.
Miltefosine
go.drugbank.com/drugs/DB09031ApprovedInvestigationalThe CDC has also recommended it as a first line treatment for free-living amebae (FLA) infections such as primary amebic meningoencephalitis and granulomatous amebic encephalitis. … Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent.
Inositol nicotinate
go.drugbank.com/drugs/DB08949ApprovedWithdrawnNicotinic acid plays an essential role in many important metabolic processes and has been used as lipid-lowering agent. … Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator.
Phenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalPhenoxyethanol has been classified as an antimicrobial and preservative by Health Canada [L2623]. … It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture.
Electrolyte imbalance
go.drugbank.com/conditions/DBCOND0015850Synonyms: Fluid/electrolyte/acid-base, Disorders of fluid, electrolyte and acid-base balanceZotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawnIt was designed and synthesized by Fujisawa Pharmaceutical Co Ltd.[A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's. … [A31857] Zotepine was never approved by the FDA.
Guanfacine
go.drugbank.com/drugs/DB01018ApprovedInvestigationalGuanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release … [L11277] Guanfacine was first described in the literature in 1974.[A189841] Guanfacine was granted FDA approval on 27 October 1986.[L11274]
Moxonidine
go.drugbank.com/drugs/DB09242ApprovedInvestigationalWithdrawnAs well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin resistance syndrome. … It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive.